| Keyword | Quelle | Titel | Autoren | Journal | Datum | Abstract (Auszug) | Link |
|---|---|---|---|---|---|---|---|
| endodontic treatment | PubMed | Effects of imaging conditions on fluorescence intensity during fluorescence-aided root canal treatment. | Saigusa, Hasegawa, Koyanagi, Sadamura, Kitamura | Photodiagnosis and photodynamic therapy | 2026 | Fluorescence-aided root canal treatment (FARCT) enables real-time visualization of protoporphyrin IX-derived red fluorescence associated with bacterial contamination during root canal treatment. However, the intensity of the detected fluorescence can vary depending on the imaging conditions. Standar... | Öffnen |
| endodontic treatment | PubMed | Comparative Histopathological Spectrum of Periapical Lesions in Root Canal-Treated and Non-root Canal-Treated Teeth. | Kandalkar, Gupta, Madhavi, Vilekar, Kuravatti, Relan, Banerjee | Cureus | 2026 | Periapical lesions represent a spectrum of inflammatory and pathological changes associated with endodontic infection. The histopathological characteristics may differ according to the previous root canal treatment status of the associated tooth. This study aimed to compare the histopathological spe... | Öffnen |
| endodontic treatment | PubMed | Influence of Therapeutic Radiation and Treatment Timing on Dislodgment Resistance of Four Root Canal Sealers: An In Vitro Push-Out Bond Strength Study. | Malik, Mallya, Athiyamaan, Lobo, Roma, Shetty, Jayaprakash | International journal of dentistry | 2026 | This in vitro study investigated whether therapeutic radiation and the timing of radiotherapy in relation to endodontic treatment influence the dislodgment resistance of four commonly used root canal sealers bonded to radicular dentin.... | Öffnen |
| endodontic treatment | PubMed | A Decade of Survival after Intracanal Repair of External Cervical Resorption in Esthetic Zone: A Case Report. | Aminsobhani, Sarkisians, Ghorvei Nossrat | Iranian endodontic journal | 2026 | External cervical resorption (ECR) in anterior teeth poses significant treatment challenges due to esthetic and periodontal considerations. While external surgical repair demonstrates superior survival rates, internal approaches may be preferable for subcrestal lesions in the esthetic zone. This cas... | Öffnen |
| endodontic treatment | PubMed | Endodontic and Orthodontic Management of a Fused Mandibular Incisor and Supernumerary: A Case Report. | Rahimi, Lalousis, Johnstone, Mahony | Iranian endodontic journal | 2026 | Dental fusion is a rare anomaly that can present unique challenges with clinical treatment. This report outlines a case of an 11-year-old who presented with fusion of a mandibular lateral incisor with a supernumerary. At presentation, the teeth were fully mature and normally responsive to pulp sensi... | Öffnen |
| endodontic treatment | PubMed | Case Report: Endodontic management of a fused maxillary lateral incisor and canine with split. | Romel, Kashyap K, Shetty, Shetty, Harikrishnan | Frontiers in dental medicine | 2026 | Dental fusion, characterized by the joining of two neighboring tooth germs during odontogenesis, is an uncommon condition affecting approximately 0.1% of the permanent dentition. The unusual anatomy of the pulp chamber and the unpredictable root canal system pose significant challenges during endodo... | Öffnen |
| root canal treatment | PubMed | Bilateral Palatal Root Agenesis of Maxillary Fourth Premolars in 2 Welsh Corgis: A Cone Beam Computed Tomography (CBCT)-Based Case Report. | Kim, Kwon, Kim | Journal of veterinary dentistry | 2026 | Palatal root agenesis of the maxillary fourth premolar (PM4) is a rarely reported developmental anomaly in dogs. This report describes 2 cases of bilateral palatal root agenesis in Welsh Corgis that had complicated crown-root fractures. Initial intraoral radiography suggested absence of the palatal ... | Öffnen |
| root canal treatment | PubMed | A Survey of Aseptic Practices in Veterinary Endodontics: Vital Pulp Treatment and Root Canal Treatment. | Steedman, Kwong, Rigby | Journal of veterinary dentistry | 2026 | The aim of this study was to characterize aseptic practices used by American Veterinary Dental College (AVDC) diplomates during vital pulp treatment (VPT) and root canal treatment (RCT) to gain a better understanding of current practices and identify areas of variability. A voluntary, anonymous web-... | Öffnen |
| root canal treatment | PubMed | Torque expression in directly printed and thermoformed clear aligners: a controlled in vitro biomechanical comparison of power ridge effects. | Khadre, Elkorashie, Elzahar, Bourauel, Fouda | Progress in orthodontics | 2026 | Torque control of anterior teeth remains a major challenge in clear aligner therapy. Power ridges have been introduced to improve buccolingual root control; however, their biomechanical performance in directly printed aligners remains insufficiently investigated. The aim of this study was to compare... | Öffnen |
| root canal treatment | PubMed | An NIR-Responsive Theranostic Gutta-Percha for Bacterial Sensing and Photothermal Disinfection during Root Canal Treatment. | Vincy, Yadav, Agarwal, Jain, Vankayala | ACS applied bio materials | 2026 | Root canal treatment (RCT) is the standard endodontic procedure for eliminating infection and preserving natural teeth. However, treatment failure can occur when residual bacteria persist within complex root canal anatomies, as current irrigation protocols do not provide direct confirmation of bacte... | Öffnen |
| artificial intelligence dentistry | PubMed | The Fundamental Necessities of Comprehensive Dental Repositories to Support the Generalisation of AI Applications in Endodontics. | Thakkar, Flores, Singh, Khan | International endodontic journal | 2026 | Artificial intelligence (AI) has the potential to reshape the healthcare industry, particularly in disease detection, diagnosis and management, as well as in supporting clinical decision-making to enhance patient care. However, realising the full potential of AI in healthcare depends on several inte... | Öffnen |
| endodontic treatment | PubMed | Tolerance of universal adhesives to saliva and gingival crevicular fluid contamination of dentin. | Tu, Dong, Liu, Liang, Chen, Xie | Dental materials : official publication of the Academy of Dental Materials | 2026 | To evaluate the dentin-bonding durability of universal adhesives under saliva and gingival crevicular fluid (GCF) contamination conditions.... | Öffnen |
| endodontic treatment | PubMed | Pulp calcification and pulp canal obliteration: from biological mechanisms to contemporary clinical management and digital navigation. | Ding, Ye | The Saudi dental journal | 2026 | Pulp calcification and pulp canal obliteration (PCO) can complicate canal identification and endodontic access. This structured narrative review synthesizes current evidence on the biological mechanisms, epidemiology, systemic, medication-related, and genetic associations, and clinical management of... | Öffnen |
| endodontic treatment | PubMed | Effect of Solvent Use on Dentinal Integrity and Filling Removal During Endodontic Retreatment: A Micro-Computed Tomography Study. | Zümrütel, Haznedaroğlu, Keleş, Kutlu Basmacı | Iranian endodontic journal | 2026 | This study evaluated, using micro-computed tomography (micro-CT), whether solvent use during endodontic retreatment influences dentinal defect formation and the removal of filling material compared with mechanical retreatment alone.... | Öffnen |
| apical periodontitis | PubMed | Association between apical periodontitis and retrograde peri-implantitis: a 10-year retrospective study. | Xia, Xu, Man, Qu, Wang | Journal of periodontal & implant science | 2026 | Retrograde peri-implantitis (RPI) has been hypothesized to be associated with apical periodontitis (AP). This retrospective study evaluated whether adjacent AP was associated with RPI and whether implant-to-lesion distance modified this association.... | Öffnen |
| apical periodontitis | PubMed | Phage-antibiotic synergy dismantles multidrug-resistant Enterococcus faecalis infection in SD rat apical periodontitis model. | Xiang, Yuan, Zeng, Xiong, Shen, Wang, Sun, Xiong, Zhou, Ji | Microbial pathogenesis | 2026 | Apical periodontitis poses a significant challenge, as 80% of cases are linked to Enterococcus faecalis, which is often protected within a biofilm. Phage-antibiotic synergy (PAS) presents a promising approach to overcoming resistance, though evidence from disease-relevant models, particularly in viv... | Öffnen |
| apical periodontitis | PubMed | Nanozymes for periodontal biofilm-associated challenges: mechanisms, platforms, and translational perspectives. | Ji, Huang, Xu, Zhu, Zhao | Frontiers in bioengineering and biotechnology | 2026 | Periodontitis is a chronic inflammatory disease driven by dysbiotic subgingival biofilms whose extracellular polymeric substance (EPS) matrix confers marked resistance to conventional therapies and host immunity, with antibiotic resistance further compounding the challenge. Nanozymes, as nanomateria... | Öffnen |
| apical periodontitis | PubMed | Case Reports of Alopecia Areata Associated With Apical Periodontitis. | Zuza, Baysan, Grcic, Bago, Bennett, Pisani, Kanagasingam | Case reports in dentistry | 2026 | Apical periodontitis is an inflammatory response of periradicular tissues caused by microbial infection within the root canal system. Alopecia areata (AA) is a T-cell mediated, autoimmune condition affecting hair follicles causing nonscarring hair loss, clinically characterised by small patches of b... | Öffnen |
| apical periodontitis | PubMed | Conservative Custom Wire and Loop-Assisted Retrieval of a Long Separated Instrument Extending Beyond the Apex: A Case Report. | Thomas, G, Ashok, P | Cureus | 2026 | Separation of endodontic instruments is a recognized procedural complication that can hinder effective canal debridement and compromise treatment outcomes, making successful retrieval essential whenever feasible. A 30-year-old female presented with pain in the upper right posterior region associated... | Öffnen |
| apical periodontitis | PubMed | Chronic Excessive Exercise Aggravates Apical Periodontitis in Mice. | Boaventura, Coasaca-Rivera, Mendes, do Amaral, da Silva, Cerri, Faria | International endodontic journal | 2026 | To investigate the effects of overtraining on the development of apical periodontitis (AP) in mice.... | Öffnen |
| apical periodontitis | PubMed | [Re-evaluation of the etiology and diagnosis of persistent periapical periodontitis]. | Li, Hou | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | The professional terms "persistent apical periodontitis" and "refractory apical periodontitis" are both used to describe clinical cases that periapical lesions fail to heal after root canal therapy. Both share similarities and differences in terms of their connotations, pathogenesis, treatment metho... | Öffnen |
| apical periodontitis | PubMed | Antibiofilm efficacy of ε-polylysine hydrochloride against Enterococcus faecalis biofilms and its biocompatibility: A promising root canal medicament. | Guo, Tan, Wen, Luo, Chen, Ruan, Wen, Ma | Dental materials : official publication of the Academy of Dental Materials | 2026 | Enterococcus faecalis (E. faecalis) is a predominant pathogen associated with refractory apical periodontitis (RAP), owing to its strong biofilm-forming ability and alkali resistance, which may compromise the antimicrobial efficacy of conventional calcium hydroxide (Ca(OH)₂)-based intracanal medicat... | Öffnen |
| apical periodontitis | PubMed | Injectable and retrievable calcium salicylate hydrogel promotes sustained periapical bone regeneration in a beagle dog model of apical periodontitis. | Aguilar Perez, Mahmoud, Cui, Hasegawa, Tripti, Ren, Luo, Fu, Sloutski, Zaliznyak, Sadasivan, Manders, Deng, Walker, Simon, Cymerman, Rafailovich | Journal of endodontics | 2026 | Persistent apical periodontitis remains a clinical challenge requiring both effective disinfection and bone regeneration. This study tested the hypothesis that an injectable, retrievable F127-DMA/CASA hydrogel facilitates periapical bone healing by combining antimicrobial action with osteogenic indu... | Öffnen |
| apical periodontitis | PubMed | Inflammatory Cytokines as Mediators of the Association Between Obesity and Chronic Apical Periodontitis. | Zhu, Yang | Journal of endodontics | 2026 | To assess genetic associations thatsupporta plausible causal interpretation of the obesity-chronic apical periodontitis (CAP) relationship, and to screen mediators including inflammatory cytokines, immune cell profiles and gut microbiota.... | Öffnen |
| biological dentistry | PubMed | Burnout among dental students: Validation of the Copenhagen Burnout Inventory. | Bashir, Alam, Wahab Khan, Bashir, Al-Jandan, Ali | Work (Reading, Mass.) | 2026 | BackgroundDental students experience physical and psychological burnout due to stress and anxiety, which affects their performance and efficacy in social and academic affairs.ObjectiveThis study aimed to assess the validity and reliability of the Copenhagen Burnout Inventory (CBI) among dental stude... | Öffnen |
| biological dentistry | PubMed | Comparative Effectiveness of Intravenous Tenecteplase versus Alteplase in Posterior Circulation Ischemic Stroke: A Systematic Review and Meta-Analysis. | Shafiq, Uddin, Hussain, Khan, Hassan, Razzak, Majid, Islam, Ahmed, Uddin, Aminpoor, Ahmed | Brain and behavior | 2026 | Posterior circulation ischemic stroke (PCIS) is associated with substantial morbidity and mortality, and the optimal intravenous thrombolytic strategy in this subgroup remains unclear.... | Öffnen |
| biological dentistry | PubMed | Assessing Hydrogel Microenvironment Density Effects on Mechanotransduction In Vitro and Bone Regeneration In Vivo. | Vignolo, Roth, Fraga, Wu, Cosgrove, Athirasala, Lin, Guldberg, Bertassoni | Journal of biomedical materials research. Part A | 2026 | For bone regeneration, matrix density is a critical determinant of scaffold performance, influencing both mechanical stiffness and biological accessibility, that is, how readily cells interact with and remodel the matrix. Here, we investigated how collagen matrix densification modulates stem cell me... | Öffnen |
| biological dentistry | PubMed | Using Q-methodology and the 3P model of learning to evaluate medicine and dentistry students' experiences with a blended anatomy laboratory design. | Dhillon, Moukarzel, Laggis, Noël, Ventura, McWatt | Anatomical sciences education | 2026 | In response to the COVID-19 pandemic, the Faculty of Medicine and Health Sciences at McGill University initiated blended curriculum delivery for first-year medicine and dentistry students in anatomy, combining limited hands-on dissection with online laboratory-adjacent activities using a 3D software... | Öffnen |
| integrative dentistry | PubMed | Herbal-derived bioactive compounds in alveolar bone regeneration: a narrative review. | Luong, Kim, Seol | Journal of periodontal & implant science | 2026 | Adequate alveolar bone volume is essential for successful implant therapy; however, current regenerative approaches are limited by donor-site morbidity, the biological passivity of bone substitutes, and safety concerns surrounding high-dose growth factors. This narrative review evaluates the potenti... | Öffnen |
| artificial intelligence dentistry | PubMed | Organoids for modeling cellular senescence and age-related pathology: From experimental reconstruction to mechanistic and translational applications. | Yang, Sun, Zhang, Ji, Liang, Wang, Yan, Zhao, Fu | Ageing research reviews | 2026 | Cellular senescence, characterized by irreversible cell cycle arrest and the acquisition of a senescence-associated secretory phenotype (SASP), is a fundamental hallmark of aging and a key driver of numerous age-related diseases. However, conventional two-dimensional cell cultures and animal models ... | Öffnen |
| biological dentistry | PubMed | Automated Detection and Segmentation of Dental Caries in Panoramic Radiographs Using YOLOv8-Based Deep Learning Model. | Putra, Astuti, Nurrachman, Savitri, Laksanti, Siddiq, Panyarak, Yoda | European journal of dentistry | 2026 | This study aimed to develop an automated dental caries localization system through detection and classification using a deep learning (DL) approach based on You Only Look Once Version 8 (YOLOv8).... | Öffnen |
| biological dentistry | PubMed | Effects of a 10-week light-intensity stretching program on arterial stiffness in third-trimester pregnant women: a randomized controlled trial. | Logan, Crandell, Williams, Hicks, Pomeroy, Liu, Rheault, Caughey, Zieff, Wilbur, Mottola, Bates-Fraser, Hinderliter, Thorp, Stoner, Yeo | European journal of obstetrics, gynecology, and reproductive biology | 2026 | To determine whether a 10-week light-intensity stretching program reduces arterial stiffness and blood pressure (BP) compared with walking in pregnant women with obesity at risk for preeclampsia.... | Öffnen |
| biological dentistry | PubMed | Association among white matter lesions, rsEEG rhythms, amyloid tau markers, and cognitive status in mild cognitive impairment patients. | Del Percio, Lizio, Noce, Carpi, Lopez, Carducci, De Bartolo, Afragola, Soricelli, Salvatore, Giubilei, Güntekin, Yener, Massa, Arnaldi, Famà, Pardini, Ferri, Lanuzza, Stocchi, Vacca, Coletti, Infarinato, Marziali, Marizzoni, Taylor, Hanoğlu, Yırıkoğulları, Frisoni, Cuoco, Cappiello, Barone, Bonanni, Biundo, Cauzzo, Fiorenzato, Antonini, De Pandis, D'Antonio, Bruno, Babiloni | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 2026 | Abnormalities in posteriorly dominant resting-state eyes-closed electroencephalographic (rsEEG) alpha rhythms are associated with cerebrospinal fluid (CSF) tau neuropathology and Mini-Mental Status Examination (MMSE) score, reflecting global cognition, in patients with mild cognitive impairment due ... | Öffnen |
| biological dentistry | PubMed | The effect of resting tongue pressure, lip-cheek pressure, and interdental force on mandibular arch collapse and mesial molar drift: A preliminary 3D finite element study. | Boosalis Toaddy, Marshall, Mueldener, Thomas, Bogert-Baird, Southard, Shin | PloS one | 2026 | Relapse of aligned mandibular anterior teeth and the progressive collapse of the mandibular anterior arch are historically significant problems for orthodontists. The etiology of this collapse, and the cause of mesial molar drift, are unknown. However, light continuous (quasi-continuous) intra-oral ... | Öffnen |
| holistic dentistry | PubMed | Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation? | Loos, Feres, Giannobile, Hasturk, Zaura | Journal of periodontal research | 2026 | Periodontitis research has traditionally focused on pathogenesis; however, understanding why some individuals remain resistant to the disease may be even more important. The concept of salutogenesis ("salutology") has evolved around the capacity to remain resilient to life's stressors. An individual... | Öffnen |
| holistic dentistry | PubMed | Healing our intergenerational wounds: a praxis of community healing envisioned by refugee young adults engaging in participatory avatar-based community circles. | Thambinathan, Wylie, Ganesh, Ramesh, Kinsella | International journal for equity in health | 2026 | Refugee communities across the world have long gathered to connect and support one another during times of crisis, and this has been well-documented. Despite the vast amount of literature pertaining to coping and resiliency among refugee communities, there is limited knowledge about refugee communit... | Öffnen |
| holistic dentistry | PubMed | Corrigendum to "Tumor-derived KLK5 activates TMEM158 | Pu, Li, Jiang, Shao, Hou, You, Yu, Jiang, Zhao, Liu, Lu, Wang, Du, Li, Zhang, Sun, Gao | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy | 2026 | Kein Abstract... | Öffnen |
| holistic dentistry | PubMed | Interdependence of dental parameters, mandibular mobility and static postural sway as well as load distribution in male subjects of advanced working age. | W, D, C, C, G, D A, D | Clinical oral investigations | 2026 | Maintaining static postural sway as well as load distribution is an essential component of overall physical stability in older age. The temporomandibular system is a measurable influencing factor due to functional interdependencies, although it has not yet been sufficiently investigated with regard ... | Öffnen |
| holistic dentistry | PubMed | Evolving aspects of oral care in older adults: a systematic review and Meta-synthesis. | Neshati, Farzaie Ardejanie, Naeimi, Pashmforosh, Askari, Rafi | BMC oral health | 2026 | The global aging population has heightened the need for comprehensive oral care in older adults, yet evolving aspects such as preventive strategies, technological advancements, and interdisciplinary approaches remain underexplored. This systematic review and qualitative meta-synthesis aimed to synth... | Öffnen |
| holistic dentistry | PubMed | A Multicentre Evaluation of Web-Based Dental Practicality Index Training for Undergraduate Treatment-Planning Education. | Parolia, Kanagasingam, Masiero, Qian, Teixeira, Miller, Patel, | European journal of dental education : official journal of the Association for Dental Education in Europe | 2026 | To evaluate whether a web-based Dental Practicality Index (DPI) training improves treatment-planning decision-making skills and confidence among undergraduate dental students.... | Öffnen |
| holistic dentistry | PubMed | Gaining a comprehensive understanding of antimicrobial resistance in dental education: a mixed methods study protocol. | Nicolau, Montgomery, Hong, Levine, Bedos, Madathil, Durand, Dawson, Chandad, Somerville, Mao, Benali Lietefti, Petersen, Junges, Macdonald | Frontiers in public health | 2026 | Antimicrobial resistance (AMR) is one of the most pressing global health challenges of the 21st century, driven in part by suboptimal prescription of antibiotics. Most antibiotic use worldwide occurs in outpatient settings, including dental practice, where dentists account for approximately 5-11% of... | Öffnen |
| holistic dentistry | PubMed | Improving psychosocial well being of older persons in Belgian nursing homes: key levers from policy to practice - a targeted review and expert consensus from the Belgian Superior Health Council. | Gerard, Agrigoroaei, Calmeyn, Gillis, Lamy, Nobels, Van Leeuwen, Van Bogaert, Van Diermen, Vermeulen, Petrovic | Acta clinica Belgica | 2026 | Belgian nursing homes increasingly care for residents with complex neurocognitive and psychiatric vulnerabilities, placing pressure on care systems structured around biomedical needs. Improving psychosocial well-being has therefore become a key quality of care challenge in long-term residential sett... | Öffnen |
| holistic dentistry | PubMed | Peripheral arterial disease: adverse impacts, disparities in outcomes, and the path ahead. | Golledge, Søgaard, Svensson, Gupta, Nikol, Reis, Mahlmann, Fowkes | Lancet (London, England) | 2026 | This is the third paper in the peripheral arterial disease (PAD) Series. The first and second papers in this Series outline that PAD affects over 300 million people worldwide and can be diagnosed by non-invasive tests, as well as that treatment requires medications to reduce modifiable risk factors ... | Öffnen |
| holistic dentistry | PubMed | Taking a spiritual history in the oral oncology setting. | Santos-Silva, Magalhaes, Calderipe, Lopes, Ávila-Pires, Epstein | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2026 | Spirituality is recognized as a dimension of health and is increasingly incorporated into supportive cancer care settings. Patients with oral cancer frequently experience profound functional, psychosocial, and existential challenges associated with their diagnosis and treatment, often leading to unm... | Öffnen |
| integrative dentistry | PubMed | Special needs dentistry training and education for preparedness in the oral health therapy curriculum. | Koh, Leadbeatter, Aley, Sohn, Pradhan | Frontiers in oral health | 2026 | Individuals with disability experience disproportionately poorer oral health outcomes and face significant barriers in accessing dental care. Despite increasing recognition of Special Needs Dentistry (SND) as a priority area, gaps remain in the education and preparedness of the oral health workforce... | Öffnen |
| artificial intelligence dentistry | PubMed | Artificial Intelligence for Diagnostic Decision-Making in Oral and Maxillofacial Surgery. | Sukegawa, Hara, Nakano, Miyake | Oral and maxillofacial surgery clinics of North America | 2026 | Artificial intelligence (AI) is increasingly being applied in oral and maxillofacial surgery; however, its primary clinical value lies in supporting decision-making rather than replacing clinicians. Surgeons must integrate diverse sources of information, including imaging, pathology, and systemic co... | Öffnen |
| integrative dentistry | PubMed | Immediate comprehensive mandibular reconstruction with fibula free flap, implant-supported dental rehabilitation, and nerve reconstruction in children: A multicenter retrospective study. | Callahan, Moles, Ghunaim, Weyh, Williams, McGue, Walker, Viet, Han | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | 2026 | Pediatric mandibular reconstruction with immediate dental rehabilitation remains challenging. We aimed to evaluate clinical, functional, and dental outcomes of immediate mandibular reconstruction using a vascularized fibula free flap (VFFF) with simultaneous jaw reconstruction (IJR) and dental impla... | Öffnen |
| integrative dentistry | PubMed | Comparison of biomechanical anchorage between apatite- and calcium titanate-modified implant surfaces. | Han, Kim, Lee, Kim, Kim, Cho | Journal of periodontal & implant science | 2026 | Implant surface chemistry and microstructure can substantially influence early osseointegration even when overall roughness is comparable. This study compared the surface characteristics, ... | Öffnen |
| artificial intelligence dentistry | PubMed | Technology-Supported Solutions to Improve Guideline-Informed Care for Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. | Manski-Nankervis, Cheungpasitporn, Garg, Graham-Brown, Griva, Samal, Stevens, Tangri, Van Spall, Cheung, King, Grams, Jadoul, Go | Kidney international | 2026 | Implementation of guideline-informed care for the prevention, detection, and management of kidney disease remains suboptimal throughout the world. In November 2025, Kidney Disease: Improving Global Outcomes (KDIGO) held a Controversies Conference on the role of technology-supported solutions to impr... | Öffnen |
| integrative dentistry | PubMed | Alginate-Methacrylate-RGD MicroSpheres (Alg-MR-MS) for cell expansion and delivery in tissue engineering. | Xavier Mendes, Duchi, Onofrillo, Zhou, Gambhir, Teixeira Do Nascimento, O'Connell, Posniak, Mukherjee, Wallace, Choong, Moulton | Biomedical materials (Bristol, England) | 2026 | Clinically relevant cell numbers are essential for many tissue engineering applications, requiring scalable expansion platforms. Microcarrier-based bioreactor systems address this demand; however, conventional non-dissolvable carriers require harsh enzymatic or mechanical detachment, reducing cell v... | Öffnen |
| integrative dentistry | PubMed | RCTE: A multi-class object detection framework for dental panoramic radiographs. | Peng, Liu, Shen, Yin, Liu, Zhou, Liu, Zhang, Hong | PloS one | 2026 | Dental panoramic radiographs play an important role in oral disease screening, computer-aided diagnosis, and clinical treatment planning. However, accurate multi-class detection remains challenging due to small lesion sizes, ambiguous anatomical boundaries, insufficient multi-scale feature represent... | Öffnen |
| zirconia dental implants | PubMed | Study on the influence of fixed dental prostheses on radiotherapy dose distribution based on dual-layer detector spectral CT imaging. | Pan, Lu, Mao, Ni, Cao | Frontiers in oncology | 2026 | Dental prostheses are often removed before radiotherapy due to metal-induced artifacts, impairing patients' quality of life. This study evaluated five non-metallic materials for fixed prostheses in head and neck radiotherapy.... | Öffnen |
| zirconia dental implants | PubMed | Overcoming the Biomechanical Limitations of Titanium-Zirconia Dental Implants: Rationale for a Novel Ti-PEEK-Zr Tri-Layered Concept. | Vacaru, Munteanu, Lupu, Deleu, Volocaru, Earar | Journal of functional biomaterials | 2026 | Kein Abstract... | Öffnen |
| ceramic dental implants | PubMed | All-on-Four Rehabilitation: A Systematic Review of Clinical Management, Workflow and Complications. | Huber, Walser, Gamma, Metzler | Dentistry journal | 2026 | Kein Abstract... | Öffnen |
| additive manufacturing zirconia | PubMed | Next-generation dental implant surface modifications for osseointegration: From nanoengineering to clinical translation. | Anil, Sweety, Mol, Singh, Suresh, Suresh | The Journal of international medical research | 2026 | This narrative review, prepared in accordance with the Scale for the Assessment of Narrative Review Articles, surveys next-generation dental implant surface modifications for osseointegration, from nanoengineering to clinical translation. Peri-implantitis affects approximately 19.53% of patients and... | Öffnen |
| ceramic dental implants | PubMed | Engineered Titanium Surfaces with Electrophoretically Deposited Graphene Oxide-Mesoporous Bioglass Nanocoatings for Enhanced Bone Regeneration and Antibacterial Activity. | Patel, Perriman, Singh, Kim | ACS biomaterials science & engineering | 2026 | Multifunctional surface engineering of titanium implants that integrates osteogenic activity with localized antibacterial function is highly desirable yet remains challenging. Here, we report a nanostructured graphene oxide/mesoporous bioactive glass nanoparticle (GO/MBGN) nanocoating fabricated via... | Öffnen |
| zirconia dental implants | PubMed | In-vitro characterization and evaluation of innovative surface modifications of zirconia implants for the optimization of hard and soft tissue management. | Angerer, Smeets, Strenge, Gosau, Bibiza, Schick, Eisenmenger, Ehlers, Henningsen, Fuest | International journal of implant dentistry | 2026 | This study focuses on the characterization and evaluation of innovative surface modifications of zirconia implants aimed at optimizing hard and soft tissue management.... | Öffnen |
| zirconia dental implants | PubMed | Effect of Angulated Screw Channel (ASC) design on the fracture resistance of implant-supported monolithic zirconia and lithium disilicate crowns: an in vitro study. | Gökten Uçar, Çölgeçen | BMC oral health | 2026 | Ti-base abutments with angulated screw channel (ASC) designs have been developed to address the esthetic challenges associated with labial screw access in anterior implant-supported single crowns, as well as the ergonomic limitations caused by restricted mouth opening in posterior crowns. Despite th... | Öffnen |
| ceramic dental implants | PubMed | Immediate implant placement with guided bone regeneration following dentoalveolar trauma - a case report. | Rogova, Konstantinova, Georgiev | Folia medica | 2026 | Dentoalveolar trauma is a common cause of tooth loss, especially in the anterior region of the maxilla. The restoration of teeth in this area is invariably challenging due to aesthetic considerations. A variety of treatment modalities are available for clinicians to select from. These include tooth-... | Öffnen |
| ceramic dental implants | PubMed | [Systematic strategy and clinical practice of minimally invasive esthetic restoration for discolored teeth]. | Peng, Liang, Ye, Zhao, Huang | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | Tooth discoloration refers to abnormal changes in tooth color and can be classified into extrinsic staining, intrinsic discoloration, and mixed discoloration. It is a common esthetic concern that may significantly affect patients' appearance and psychological well-being. With the continuous developm... | Öffnen |
| zirconia dental implants | PubMed | Comparison between dual-angle periapical technique and cone-beam computed tomography in the identification of a second canal in mandibular incisors in the presence of a zirconia implant: An in vitro study. | Andrade-Bortoletto, de Oliveira, Silva, Réa, Leal, Ruiz, Freitas | Imaging science in dentistry | 2026 | To compare the accuracy of the dual-angle periapical technique (DPT) and CBCT acquired with two protocols in identifying lower incisors with a second canal adjacent to a zirconia implant.... | Öffnen |
| additive manufacturing zirconia | PubMed | In Situ Construction of β-TCP-Containing Bioactive Interfaces on Additively Manufactured Al | Zhang, Li, Li, Luo, Cheng, Yang, Li, Wang | Advanced healthcare materials | 2026 | High-performance zirconia ceramics possess excellent mechanical reliability but are limited by biological inertness for load-bearing implant applications. Herein, stereolithography (SLA) additive manufacturing combined with microwave-assisted liquid-phase deposition was developed to construct a β-tr... | Öffnen |
| zirconia implants | PubMed | Clarifying the Experimental Unit and the Evidence for Preserved Osseointegration in a Zirconia-Silver Coating Study. | Yang, Zhang | Annals of biomedical engineering | 2026 | Brogini et al. reported an integrated assessment of a zirconia-silver coating for titanium implants and concluded that osseointegration was preserved. We seek clarification regarding the analytical unit and the evidential basis for that interpretation. The Methods describe 12 control and 12 coated i... | Öffnen |
| zirconia implants | PubMed | Impact of restoration design and material on the mechanical behavior of implant-supported monolithic CAD-CAM single crowns: An in vitro study. | Bishti, Bingöl, Wolfart, Tuna | Journal of prosthodontic research | 2026 | To evaluate the effects of crown design and restorative material on screw loosening and load-bearing performance of monolithic single-implant restorations after cyclic loading.... | Öffnen |
| 3D printed zirconia implants | PubMed | Fibroblast and bacterial adhesion on a 3D-printed polyetheretherketone-based implant material. | Branco, de Souza, El-Amier, Silva, Zimmermann, Mata, Marques | European journal of oral sciences | 2026 | This study investigated fibroblast and bacteria proliferation on polyetheretherketone (PEEK)-implant material 3D-printed by fused deposition modeling (FDM) in comparison to titanium (cp-Ti) and zirconia (ZrO... | Öffnen |
| zirconia dental implants | PubMed | Fracture modelling of zirconia crowns in dental implant systems using XFEM, phase-field methods, and Weibull statistics. | Jalali, Raman, Abolghasemi, Mostafavi, Azhari | Dental materials : official publication of the Academy of Dental Materials | 2026 | This study aimed to develop a continuum-scale computational workflow for assessing fracture behaviour of zirconia crowns in dental implant systems under ISO 14801 loading conditions.... | Öffnen |
| zirconia dental implants | PubMed | Factor-specific clinical evidence for zirconia dental implants: A systematic review and evidence map. | Son, Lee | Journal of dentistry | 2026 | To map clinical evidence on implant-system factors and post-placement outcomes of zirconia dental implants and identify reporting and independent-replication gaps.... | Öffnen |
| zirconia implants | PubMed | The Effect of Surface Treatment Methods on the Surface Characteristics and Biological Activity of Zirconia Implants. | Fu, Li, Li, Lu, Lan, Niu, Han | Journal of biomedical materials research. Part B, Applied biomaterials | 2026 | Zirconia implants are promising alternatives to titanium, yet optimal surface treatment protocols that preserve their surface properties and biocompatibility are not well-established. This study aimed to evaluate the effects of various surface treatment methods-ethylene oxide (EO), hydrogen peroxide... | Öffnen |
| zirconia implants | PubMed | Post-opening storage temperature and its impact on zirconia bonding performance of a universal adhesive system. | Hsu, Lai, Kang, Feng, Wei, Peng | The Journal of prosthetic dentistry | 2026 | Universal adhesives have been widely combined with resin cements for bonding to zirconia. While the shelf life of unopened adhesive has been well documented, the post‑opening stability, specifically the interaction with ambient operatory temperature, remains unknown for zirconia bonding.... | Öffnen |
| zirconia dental implants | PubMed | Cleaning Efficacy and Surface Alterations of Titanium and Zirconia Implant Abutments Following Mechanical Instrumentation: An In Vitro Study. | Kamel, Spahr, Badgery-Parker, Divnić-Resnik | Clinical oral implants research | 2026 | To evaluate the cleaning efficacy, quantitative and qualitative surface modifications of titanium (Ti) and zirconia (Zr) abutments following instrumentation with twelve mechanical instrumentation modalities.... | Öffnen |
| zirconia dental implants | PubMed | Clinical outcomes of a two-piece zirconia dental implant system. | Mehnert, Noack, Simon, Beuer, Pieralli | International journal of implant dentistry | 2026 | Data on market-available two-piece zirconia (ZrO₂) dental implants are limited. Therefore, the aim of this retrospective study was to evaluate the clinical performance of a commercially available ZrO₂ implant system over a 24-month period.... | Öffnen |
| NICO | PubMed | Synergistic sulfur regulation and interface engineering in MOF-derived hierarchical hollow NiCo@NCNTs/S for efficient microwave absorption. | Xu, Zhou, Yang, Mu, Jin, Liu, Yang, Lei, Yang | Journal of colloid and interface science | 2026 | Although MOF-derived materials are promising candidates for microwave absorption, precisely regulating their electromagnetic behavior through microstructure engineering remains a considerable challenge. Herein, a synergistic strategy integrating hollow hierarchical architectures with heteroatom dopi... | Öffnen |
| NICO | PubMed | Gastrointestinal symptom profiles after resection of esophageal or gastric cancer. | Lee, Katsimpokis, van Erning, Nieuwenhuijzen, van Laarhoven, Gisbertz, Klarenbeek, Jeene, Pouw, Noteboom, Verhoeven, Vissers | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer | 2026 | Persistent gastrointestinal symptoms are common after esophagectomy or gastrectomy, which frequently co-occur and significantly decrease quality of life. This study aimed to identify gastrointestinal symptom profiles over the first-year post-surgery and to explore changes over time.... | Öffnen |
| NICO | PubMed | Cultural proximity reveals a local premium in collective memory. | Macedo, Oyarzun, Candia, Hidalgo | PNAS nexus | 2026 | Collective memory-shared information about the past that shapes a group's identity-is often examined through constructs such as familiarity or salience, conflating its local and global components. Here, we untangle these components using multilingual online attention traces for over 50,000 Wikipedia... | Öffnen |
| NICO | PubMed | Trimetallic synergy in Ni | Sultana, Brock | RSC advances | 2026 | Developing earth-abundant and stable oxygen evolution reaction (OER) catalysts remains important for practical utilization of alkaline water electrolysis. Previous efforts revealed that bimetallic, Mn-containing phosphides, including Co... | Öffnen |
| NICO | PubMed | Cobalt-nickel sandwich-type Dawson polyoxometalates as bifunctional OER/ORR electrocatalysts: the influence of metal arrangement. | Marques, Mbomekallé, Teillout, de Oliveira, Fernandes, Fernandes | Dalton transactions (Cambridge, England : 2003) | 2026 | The rising global need for sustainable energy has intensified research into environmentally friendly energy conversion technologies, such as fuel cells and electrochemical water splitting devices. The efficiency of these technologies is strongly influenced by the activity of electrocatalysts that en... | Öffnen |
| NICO | PubMed | Donor-Selective NiCo-LDH Templating Directs Polymer Assembly for Enhanced Exciton Transport in Efficient Organic Solar Cells. | He, Zeng, Liu, Lin, Yang, Zhang, Fu, Pu, Jiang, Zhao, Zheng, Lu, Liu, Lai, Li | Advanced materials (Deerfield Beach, Fla.) | 2026 | Organic solar cells (OSCs) have achieved remarkable progress, yet improving exciton utilization in polymer donors remains challenging due to their intrinsically limited exciton diffusion length (L... | Öffnen |
| NICO | PubMed | Quantifying the Dynamics of Network Detachment Across Scientific, Technological, Commercial, and Pharmacological Domains. | Wang, Jin, Song, Bjelland, Uzzi, Wang | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 2026 | Despite the vast literature on complex network dynamics, our understanding of the network detachment process remains limited. This understanding is essential for deeper insight into network evolution. Here, we analyze four large-scale datasets that capture the structural patterns of detachment acros... | Öffnen |
| NICO | PubMed | Phytic Acid-Induced Oxygen Vacancies in Self-Supporting NiCo Metal-Organic Frameworks for Efficient Oxygen Evolution Reaction. | Ye, Zhang, Liu, Zang, Nadeem, Bao, Bando, Yuan, Dou | Small (Weinheim an der Bergstrasse, Germany) | 2026 | The sluggish kinetics of the oxygen evolution reaction (OER) impede efficient water electrolysis, motivating the development of robust, non-precious-metal electrocatalysts. Here, we construct a self-supported bimetallic metal-organic framework precatalyst (PAx-NiCo-BDC) through a two-step strategy u... | Öffnen |
| NICO | PubMed | Defect-engineered lignite-derived carbon/NiCo | Faruk, Pitchai Kaveri, Sandeep, Dutta, Merugumolu, Nagaraja, Madhyastha, Gunasekaran, Santosh, Bhatt, Chandrashekarappa Revanasiddappa | RSC advances | 2026 | The development of robust materials for nonenzymatic glucose sensing remains challenging due to material cost, instability, and limited mechanistic understanding. Moreover, many existing reports lack validation using real samples, making their real-world applicability uncertain. We report a novel de... | Öffnen |
| NICO | PubMed | Review of Multi-Scale Bridge Monitoring: An Information-Centric Framework Integrating Ground-Penetrating Radar, Distributed Optical-Fibre Sensing, and Satellite Remote Sensing for Bridge Digital Twins. | Zou, Li, Munisami, Nico, Alani | Sensors (Basel, Switzerland) | 2026 | Bridge infrastructure worldwide is under increasing pressure from ageing assets, growing traffic demand, environmental deterioration, and the need for more effective lifecycle management. Although bridge-monitoring technologies have developed rapidly, much of the existing research has focused on ind... | Öffnen |
| cavitational osteonecrosis | PubMed | Human Umbilical Cord Mesenchymal Stem Cells Protect Against Steroid-Induced Osteonecrosis of the Femoral Head Through Hippo Pathway. | Xing, Cai, Chen, Xu, Zhang, Zhong, Zhou, Peng | Biomedicines | 2026 | Kein Abstract... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Neuralgia-inducing cavitational osteonecrosis (NICO): A scoping review of a controversial concept in orofacial pain. | Biancardi, Cardoso, de Paula Almeida, Quirino, Sarmento, Rubira, Rubira-Bullen | Archives of oral biology | 2026 | Neuralgia-Inducing Cavitational Osteonecrosis (NICO) is a debated diagnostic entity proposed as a cause of chronic orofacial pain. Despite ongoing clinical use, systematic evaluations integrating historical foundations and methodological gaps remain limited.... | Öffnen |
| cavitational osteonecrosis | PubMed | Jawbone Cavitations: Current Understanding and Conceptual Introduction of Covered Socket Residuum (CSR). | Ghanaati, Heselich, Lechner, Sader, Bouquot, Al-Maawi | Bioengineering (Basel, Switzerland) | 2026 | Jawbone cavitations have been described for decades under various terminologies, including neuralgia-inducing cavitational osteonecrosis (NICO) and fatty degenerative osteolysis of the jawbone (FDOJ). Their biological nature and clinical relevance remain controversial. The present review aimed to su... | Öffnen |
| jawbone osteonecrosis | PubMed | Mechanism-Oriented Biomaterial Strategies for Bone Regeneration in BRONJ: From Pathological Barriers to Evidence-Matched Repair. | Jiang, Liao, Shi, Song, Luo, Li, Zhang | Biomolecules | 2026 | Bisphosphonate-related osteonecrosis of the jaw (BRONJ) remains a challenging complication of bisphosphonate therapy because jaw extraction sockets exposed to bisphosphonates represent impaired wound environments rather than ordinary bone defects. This narrative review summarizes clinical, cellular,... | Öffnen |
| jawbone osteonecrosis | PubMed | Oral microbiome and lesion-associated microbiological findings in medication-related osteonecrosis of the jaw: a systematic review and evidence map. | Yin, Du, Wan | Frontiers in cellular and infection microbiology | 2026 | Medication-related osteonecrosis of the jaw (MRONJ) may involve microbial colonization, anaerobic organisms, and biofilm formation, but whether it has a reproducible microbial signature remains unclear. We mapped the human microbiological evidence in MRONJ.... | Öffnen |
| jawbone osteonecrosis | PubMed | Frequency and Systemic Associations of Focal Low-Trabeculation/Low-Density Intramedullary Jawbone Findings: A Retrospective CBCT Study. | Dominiak, Niemczyk, Pitułaj, Świenc, Dominiak, Sławecki, Janek, Matys | Journal of clinical medicine | 2026 | Kein Abstract... | Öffnen |
| jawbone osteonecrosis | PubMed | Small Intramucosal Sequestra in Medication-Related Osteonecrosis of the Jaw: A Case Series. | Hayashi, Koizumi, Okumura, Yamada, Nagata, Kurohara, Murata, Shimizu, Hayashi, Yamanaka, Arai | Diagnostics (Basel, Switzerland) | 2026 | Kein Abstract... | Öffnen |
| jawbone osteonecrosis | PubMed | How to Prepare Patients Receiving Antiresorptive Therapy for Tooth Extraction: A Narrative Review. | Bielecki-Kowalski, Sokalski, Majorczyk, Bielecka-Kowalska, Klosek | International journal of molecular sciences | 2026 | Bisphosphonates (BPs) and Denosumab (DMB) are antiresorptive agents (AA) commonly used in treatment of osteoporosis, multiple myeloma (8.0%), breast cancer (3.3%), prostate cancer (2.9%) and other malignancies (0.7%), bone metastases, and cancer-induced hypercalcemia. However, this therapy is associ... | Öffnen |
| jawbone osteonecrosis | PubMed | [Research progress of mesenchymal stem cells in the treatment of medication-related osteonecrosis of the jaw]. | Huang, Peng, Liu | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication characterized primarily by jawbone necrosis, induced by bisphosphonates or other targeted agents for systemic diseases. With the advancement of systemic anticancer therapies, the survival of patients with advanced malignanc... | Öffnen |
| jawbone osteonecrosis | PubMed | [Comparison of treatments for osteoradionecrosis of the jaw and medication-related osteonecrosis of the jaw]. | Wang, He | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | Osteonecrosis of the jaw (ONJ) is an inflammatory and necrotic disease affecting the jawbones. The most prevalent forms include osteoradionecrosis of the jaw (ORNJ) following radiotherapy for head and neck malignancies, and medication-related osteonecrosis of the jaw (MRONJ) triggered by long-term u... | Öffnen |
| jawbone osteonecrosis | PubMed | [Focusing on the challenges in the diagnosis and treatment of osteonecrosis of the jaw: toward precision therapeutic strategies]. | He | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | Osteonecrosis of the jaw (ONJ) is one of the most challenging diseases in the field of oral and maxillofacial surgery, mainly including osteoradionecrosis of the jaw (ORNJ) and medication-related osteonecrosis of the jaw (MRONJ). With the continuous improvement in comprehensive treatment strategies ... | Öffnen |
| jawbone osteonecrosis | PubMed | Mitigating thermal risk in guided implant surgery: Hollow-guide and alternative designs. | Weatherington | Clinical advances in periodontics | 2026 | The generation of heat during osteotomy preparation is a significant risk factor for thermal osteonecrosis, which may lead to implant failure. While static surgical guides enhance placement accuracy, they can physically obstruct the flow of external coolant, paradoxically increasing the risk for the... | Öffnen |
| jawbone osteonecrosis | PubMed | Proteome and miRNAs Expression in Medication-Related Osteonecrosis of the Jaw. | Allegra, De Salvo, Marcianò, Polito, Stagno, Carleo, Costanzo, Caterino, Ragusa, Licitri, Drago, Gasparo, Alberti, Khouyyi, Siniscalchi, Oteri, Bini, Macaione, Bianchi, Aguennouz | International journal of molecular sciences | 2026 | Medication-related osteonecrosis of the jaw (MRONJ) is a complex condition associated with the use of antiresorptive drugs, such as bisphosphonates and denosumab. The condition is characterized by the presence of exposed bone in the maxillofacial region that fails to heal. MRONJ remains highly intra... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Immunoregenerative remodeling of the dermal microenvironment induced by platelet-rich plasma in atrophic abdominal striae. | de Castro Roston, Roston, de Arruda Camargo, de Oliveira, Reis, Luzo, Fávaro | Tissue & cell | 2026 | Striae distensae are chronic dermal lesions characterized by extracellular matrix disruption, fragmentation of collagen and elastic fibers, fibroblast dysfunction, and impaired tissue homeostasis. Although platelet-rich plasma (PRP) has regenerative potential, the temporal tissue and immune changes ... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Expression of the Chemokine (C-C Motif) Ligand 5 (CCL5) in Oral Lichen Planus and Oral Lichenoid Lesions: A Systematic Review. | Rampersaud, Al-Azzawi, Aria, Hijazi, Celentano, Fortuna | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology | 2026 | RANTES, a chemokine involved in regulating inflammatory responses, has been implicated in the pathogenesis of various diseases, including oral lichen planus (OLP). In this condition, the interaction between C-C motif ligand 5 (CCL5) and CC motif chemokine receptor 5 (CCR5) may contribute to the dest... | Öffnen |
| RANTES CCL5 dentistry | PubMed | DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion. | Wang, Zhang, Sun, Xu, Gu, Jin, Zhu, Zhang, Yan | Progress in orthodontics | 2026 | Orthodontic tooth movement (OTM) is a complex process involving periodontal tissue remodeling, and safe strategies to accelerate OTM remain a research focus. DMXAA (Vadimezan), a non-toxic immune-modulating drug with established clinical trial data, stimulates the secretion of pro-inflammatory cytok... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Integrated Single-Cell Transcriptomics Identifies γδ T-Cell Heterogeneity and a Candidate HLA-E-NKG2A Regulatory Axis in Pancreatic Ductal Adenocarcinoma. | Mandal, Hasan, Dhali, Maji | Cancers | 2026 | Kein Abstract... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Transcriptomic characterization of platelet-rich fibrin-induced macrophage responses identifies U937 cells as a sensitive bioassay. | Panahipour, Huang, Zampino, Miron, Gruber | Frontiers in immunology | 2026 | Platelet-rich fibrin (PRF) is extensively utilized to enhance localized tissue healing, a process that critically depends on the transient polarization of macrophages toward a pro-inflammatory phenotype. Given that PRF, like other blood clot derivatives, may intrinsically modulate macrophage behavio... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Moderate Aerobic Training Causes Muscle Wasting in a DMBA-Induced Sarcoma Rat Model. | Correia, Veras, Tavares, Batista, Cury, Oliveira, Fernandez, Counts, Gaafer, Ota, Frigo, Rodrigues, Sampaio, Chaves-Neto, Carvalho, Zimmers, Teixeira | International journal of molecular sciences | 2026 | Cancer cachexia, characterized by severe body weight loss, negatively affects patient quality of life and survival. Although moderate exercise benefits healthy and chronically ill individuals, and the effect of exercise in cachexia generally appears beneficial, conflicting results have been reported... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Increased inflammation, disturbed extracellular matrix remodeling and reduced parotid and submandibular salivary gland function in male Wistar rats with type 2 diabetes. | Kotowska-Rodziewicz, Zalewska, Żendzian-Piotrowska, Zukowski, Lo Giudice, Lo Giudice, Maciejczyk | Dental and medical problems | 2026 | Insulin-independent type 2 diabetes mellitus (DM2) causes numerous organ complications, some of which involve the oral cavity. However, to date, the causes of reduced salivary secretion in patients with DM2 remain unclear.... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Nuclear Factor I-B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription. | Chen, Rui, Fan, Yang, Geng, Lu, Ni, Huan, Shi, Wu, Yin, An, Lu, Zhao, Li | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 2026 | Metabolic dysfunction-associated steatohepatitis (MASH) is a significant contributor to liver fibrosis due to hepatic stellate cells (HSCs) activation. The anti-apoptotic gene Nuclear Factor I-B (NFIB) has been implicated in regulating cell proliferation and differentiation in the context of liver i... | Öffnen |
| focal infection theory dentistry | PubMed | [Historical evolution and current research of the odontogenic focal theory]. | Xu, Duan, Zhou | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology | 2026 | Proposed in the early 20th century, the focal infection theory hypothesizes that teeth with dental caries, endodontic-periapical/periodontal diseases, plus impacted teeth and residual roots, might act as infection foci, inducing pathologies in distant organs including respiratory tract, gastrointest... | Öffnen |
| oral systemic health | PubMed | gutMDisorder v3.0: an updated database for dysbiosis of the gut and oral microbiota in phenotypes and interventions. | Guan, Qi, Liu, Li, Zhang, Gao, Chen, Cheng, Zhang | Nucleic acids research | 2026 | Microbiota plays an essential role in host health, and dysbiosis of microbial communities has been widely associated with diverse phenotypes and intervention responses. With the rapid development of microbiome research, microbiome studies are no longer restricted to gut-derived samples, and the oral... | Öffnen |
| oral systemic health | PubMed | Pharmacokinetic Interaction Between Eperisone and Ojeok-San in Healthy Subjects. | Keum, Choi, Mo, Yoon, Park, Kim, Lee, Kim | Clinical pharmacology in drug development | 2026 | Ojeok-san is a traditional multiherbal formulation commonly prescribed for musculoskeletal symptoms in East Asian medicine. The concomitant use of herbal medicines and conventional pharmacotherapy is common in patients with musculoskeletal disorders; however, the pharmacokinetic (PK) interactions be... | Öffnen |
| oral systemic health | PubMed | Broad multiplex respiratory panel implementation and antibiotic prescribing in US emergency and urgent care departments: a staggered-adoption study. | Al Mohajer, Phe, Teran, Lasco | Infection control and hospital epidemiology | 2026 | To evaluate the association between department-level implementation of broad multiplex respiratory pathogen panels and antibacterial prescribing.... | Öffnen |
| oral systemic health | PubMed | Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut-Liver Axis. | Ji, Fang, Zhang, Xu, Guo, Chen, Zhu, Wen, Chen, Zhu, Xu, Yin | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 2026 | Metabolic dysfunction-associated steatohepatitis (MASH) currently lacks effective targeted therapeutics, while interleukin-22 (IL-22) as a potential treatment approach faces challenges in the clinical translation due to off-target risks associated with systemic delivery. To address this limitation, ... | Öffnen |
| oral systemic health | PubMed | Trigeminal sensory neuropathy developing as a late complication after the treatment of surgically induced necrotizing scleritis following pterygium surgery: a case report and literature review. | Karasu, Kandemir Beşek, Kesim, Yılmaz Tuğan | BMC ophthalmology | 2026 | Surgically induced necrotizing scleritis (SINS) is an immune-mediated disease that occurs infrequently after ocular procedures, with latency ranging from days to years. There are various early and late complications that can negatively affect quality of life after SINS. This case report aims to pres... | Öffnen |
| oral systemic health | PubMed | Oral and Maxillofacial Manifestations of Rheumatologic Disease. | Schultz, Sullivan, Hirsch | Rheumatic diseases clinics of North America | 2026 | The oral cavity is the gateway to systemic health, and rheumatologic diseases are no exception. This article will cover some common and uncommon rheumatologic conditions with head and neck and oral manifestations. The article will emphasize etiopathogenesis, clinical presentations, and management of... | Öffnen |
| oral systemic health | PubMed | Oral Mucosal and Salivary Gland Involvement in Select Rheumatic Diseases. | Kelsch | Rheumatic diseases clinics of North America | 2026 | This article will discuss the oral mucosal and salivary gland manifestations of several rheumatologic diseases including autoimmune conditions such as Sjogren syndrome and systemic scleroderma as well as other inflammatory conditions such as lupus erythematosus and granulomatosis with polyangiitis.... | Öffnen |
| oral systemic health | PubMed | Patient Reported Outcome Measures of Head and Neck Cancer Patients Treated With Curative Intent Radiotherapy Within the Head and Neck 5000 Cohort. | Growcott, Dembrey, Odding, Bellou, Dudding, Hargreaves | Clinical oncology (Royal College of Radiologists (Great Britain)) | 2026 | We used the Head and Neck 5000 (HN5000) cohort to assess whether age ≥70 yrs and World Health Organization (WHO) performance status (PS) ≥2 were associated with increased severity of patient-reported acute, late, and very late toxicity or reduced rate of completing a prescribed course of radiotherap... | Öffnen |
| oral systemic health | PubMed | Population pharmacokinetics modeling of albendazole and its active metabolite, albendazole sulfoxide in mass drug administration against lymphatic filariasis. | Alshehri, King, Murry | Antimicrobial agents and chemotherapy | 2026 | Albendazole (ALB), a benzimidazole antiparasitic, is widely used in mass drug administration (MDA) campaigns against lymphatic filariasis (LF). It is rapidly metabolized to its active form, albendazole sulfoxide (ALB-OX), which exhibits considerable interindividual variability (IIV) in pharmacokinet... | Öffnen |
| oral systemic health | PubMed | Antitumor efficacy and safety profile of gallic acid in the murine sarcoma 180 model. | Heiden, Costa, Alfaia Silva, Carvalho, Amaral, Rivero, Modolo, Gondak, de Albuquerque-Júnior | Medical oncology (Northwood, London, England) | 2026 | Gallic acid (GA) is a plant-derived polyphenol with recognized anticancer activity, but in vivo evidence, especially in mesenchymal solid tumors, remains limited. This study investigated the antitumor effects and mechanistic pathways of GA in the murine Sarcoma 180 (S-180) model. Fifty male Swiss mi... | Öffnen |
| periodontitis cancer risk | PubMed | New periodontal phenotype classification in patients with different types of malocclusion and dental crowding. | Al-Sosowa, Abdulghani, Meng, Zhu, Ding | Journal of periodontology | 2026 | The periodontal phenotype plays a critical role in periodontal stability and orthodontic risk assessment. However, an integrated evaluation of soft- and hard-tissue periodontal characteristics across various sagittal and vertical skeletal patterns and dental crowding remains limited. This study appl... | Öffnen |
| fusobacterium nucleatum | PubMed | The association between periodontal disease and lung cancer: a re-evaluation of independent causal relationships in the presence of smoking as a confounder and an exploration of potential mechanisms. | Liu, Yang, Zhang | Frontiers in cellular and infection microbiology | 2026 | Periodontal disease and lung cancer are major global health burdens, and epidemiological evidence suggests a potential association between them. However, whether this relationship is independent of smoking-a strong common risk factor-remains controversial. This review systematically summarizes curre... | Öffnen |
| periodontitis cancer risk | PubMed | Periodontal disease and risk of dementia: a systematic review and meta-analysis. | D'Souza, Bhagirath, Verma, Johnson, Wang, Shenoy | Evidence-based dentistry | 2026 | Periodontal disease is a biofilm-associated, host-mediated inflammatory disease characterized by inflammation and destruction of the tooth-supporting tissues. An association between periodontal disease and adverse cognitive outcomes, including dementia, has been proposed; however, findings across st... | Öffnen |
| periodontitis cancer risk | PubMed | Association between climate change and oral health outcomes: a systematic review of time-series studies. | Bhadania, Mehta, Noor, Das, Mathur | BDJ open | 2026 | This Systematic review aimed to assess the association between short term environment exposures and oral health outcomes using evidence from time-series studies.... | Öffnen |
| periodontitis cancer risk | PubMed | Antibacterial efficacy of dental floss coated with green synthesised zinc oxide nanoparticles using Calotropis gigantea flower extract: An in vitro study. | H, Kumar, Dhanyashree, Shastry, Prabhu, Hegde | Dental materials journal | 2026 | Dental floss aids in mechanical plaque removal by cleaning interdental areas, reducing periodontal disease risk, and enabling medicament delivery. This study evaluated the antimicrobial and antibiofilm properties of green-synthesized zinc oxide nanoparticles (ZnONPs)-coated dental floss against earl... | Öffnen |
| periodontitis cancer risk | PubMed | The oral und systemic health risks of sugar consumption: an umbrella review. | Woelber, Wirth, Dallmer-Zerbe, Tennert | Clinical oral investigations | 2026 | The recommendation of free sugar reduction in dental practice is mostly given with regard to caries prevention but has also further health impacts. This umbrella review aimed to comprehensively display the shared health consequences of sugar consumption in both oral and general health.... | Öffnen |
| periodontitis cancer risk | PubMed | Smoking prevalence, perceptions and cessation practices among dental hygienists in Japan: A cross-sectional study. | Watanabe, Inagaki, Watanabe, Niino, Kanamori, Kawano, Shimokawa, Kosaka, Inukai | Tobacco induced diseases | 2026 | Smoking is a risk factor for oral diseases such as periodontal disease and oral cancer. Dental hygienists play an important role in oral health promotion and smoking cessation support. The aim of this study was to clarify the smoking status, tobacco perceptions, and smoking cessation support among d... | Öffnen |
| periodontitis cancer risk | PubMed | Sleep Quality and Risk of Periodontal Disease: A Systematic Review and Meta-Analysis. | Nan, Kang, Wei, Li, Chen, Cheng | Oral diseases | 2026 | Sleep regulates immune and inflammatory processes and may influence periodontal health, though evidence remains inconsistent. This meta-analysis evaluated the association between sleep characteristics, including sleep quality and sleep duration, and periodontal disease (PD).... | Öffnen |
| periodontitis cancer risk | PubMed | The oral-lung axis in lung cancer: microbial translocation, immune reprogramming, and clinical implications. | Liu, Ding, Lu, Song, Li, Chen, Cui | Frontiers in immunology | 2026 | The oral-lung axis describes microbial and inflammatory exchange between the oral cavity and the lower respiratory tract. Its relevance to lung cancer is supported by the detection of oral-associated taxa in lower-airway samples, epidemiological links between periodontal disease and lung cancer risk... | Öffnen |
| periodontitis cancer risk | PubMed | Computational and AI-Enabled Imaging Biomarkers for Predicting and Assessing Immunotherapy Response in Oral Squamous Cell Carcinoma: A Systematic Review with Functional Meta-Synthesis. | Ardila, Vivares-Builes, Pineda-Vélez | Medical sciences (Basel, Switzerland) | 2026 | Kein Abstract... | Öffnen |
| root canal cancer correlation | PubMed | Effect of Intracapsular Pressure on Pulp Sensitivity in Teeth Affected by Jaw Cysts: A Clinical Study Combined With Finite Element Analysis. | Zhou, Mao, Lin, Lu, Lai, Wang, Chen | International dental journal | 2026 | The objective of this research was to explore the relationship between intracapsular pressure (ICP) and pulp sensitivity in teeth affected by jaw cysts and to examine clinical and radiographic factors associated with variations in ICP.... | Öffnen |
| root canal cancer correlation | PubMed | Why was the concordance rate of imaging and clinical diagnosis in cemento-osseous dysplasia low? A retrospective study of 55 cases. | Li, Zheng, Tang, Shi, Ren, You, Liu | BMC oral health | 2026 | The World Health Organization (WHO) recommends that cemento-osseous dysplasia (COD) be diagnosed based on imaging findings, avoiding biopsy when possible. This study aimed to evaluate the concordance between imaging and clinical diagnoses in 55 COD patients, and to identify key clinical and radiogra... | Öffnen |
| oral microbiome cancer | PubMed | A microproteome screen identifies immunomodulatory bacterial microproteins encoded in expanded gene arrays in Leptotrichia. | Ragheb, Kiguchi, Lin, Hoffman, Daigh, Chakraborty, Doyle, Grieshop, Lin, Maghini, Spees, Bintu, Bassik, Bhatt | bioRxiv : the preprint server for biology | 2026 | The human microbiome exerts broad influence in health and disease with associative studies implicating the microbiome in influencing immunity, cancer outcomes, and neurodegeneration. However, the molecular mediators of microbe-host communication remain poorly defined. Bacterial microproteins from th... | Öffnen |
| oral microbiome cancer | PubMed | Oral microbial nitrate metabolism is associated with lower prevalence of prediabetes. | Zhao, Haryono, Lai, Seah, Tang, Lim, Febriana, Lee, Tan, Fu, Yip, Preshaw, Williams, Toh, Lee, Goh | Cell reports. Medicine | 2026 | The oral microbiome is a key microbial interface for dietary or oral nitrate metabolism, yet its role in early glycemic dysregulation remains poorly defined. In a population-based cohort (n = 472), we perform metagenomic profiling of tongue dorsum microbiomes and identify 11 taxa and nine microbial ... | Öffnen |
| oral microbiome cancer | PubMed | Gastrointestinal-Responsive Jelly Fig-Alginate Microgels for Restoring Intestinal Barrier Homeostasis through Microbiota-Metabolite Remodeling. | Wang, Hu, Li, Xu, He | ACS applied materials & interfaces | 2026 | Oral biomaterials capable of protecting natural bioactives during gastrointestinal transit while restoring intestinal barrier function offer a promising strategy for inflammatory bowel disease intervention. Here, we developed edible Jelly Fig (Ficus awkeotsang Makino, JF) pectin-alginate composite m... | Öffnen |
| oral microbiome cancer | PubMed | Thymol-based derivatives as anticancer agents: design, synthesis, biological evaluation, and molecular docking studies. | Faris, Di Rienzo, Klena, Krizanova, Turkez, Men, Arslan, Arslan, Cadirci, Kim, Mardinoglu, Valentinuzzi, Del Boccio, Di Stefano, Cacciatore | Bioorganic chemistry | 2026 | Seventeen thymol-based derivatives (TM1-7, TBr1-2, TCl1-4, and TF1-4) were designed and synthesized by esterification with halo- and non-halogenated cinnamoyl molecules employing a key-step coupling reaction. All derivatives were chemically characterized (... | Öffnen |
| oral microbiome cancer | PubMed | Beyond antibiotics: collateral damage to the gut microbiome during cancer therapy. | Jin, Lv, Jiang, Jia | Frontiers in microbiology | 2026 | Antibiotics are major drivers of microbiome disruption in oncology, but they do not fully explain the ecological changes observed during cytotoxic treatment. The central question of this Mini Review is when chemotherapy-associated microbiome change should be interpreted as transient compositional va... | Öffnen |
| oral microbiome cancer | PubMed | Sciadonic acid ameliorates cognitive impairment in APP/PS1 mice with concomitant modulation of gut microbiota and brain metabolism. | Xie, Zheng, Li, Zheng, Shen, Xiang, Chen | Food & function | 2026 | Sciadonic acid (SCA) is a fatty acid derived from ... | Öffnen |
| fusobacterium nucleatum | PubMed | Metabolic effects of periodontal pathogens | Gopinath, Selvakumar, Sekar, Mohammed, Li | Journal of Taibah University Medical Sciences | 2026 | Periodontal pathogens are increasingly recognized as key regulators of cancer biology. However, their roles in modulating metabolism-related gene expression in colorectal cancer remain poorly understood.... | Öffnen |
| oral microbiome cancer | PubMed | Heterogeneous mechanisms, risk stratification, and translational advances in the malignant transformation of oral potentially malignant disorders to oral squamous cell carcinoma. | Yu, Peng, Cheng, Xu, Wang, Xiao, Wei, Huang, He, Wang | Frontiers in molecular biosciences | 2026 | Oral potentially malignant disorders (OPMDs) represent important precursor conditions in the development of oral squamous cell carcinoma (OSCC) and provide a critical window for early prevention, risk assessment, and precision intervention of oral cancer. Oral leukoplakia, proliferative verrucous le... | Öffnen |
| oral microbiome cancer | PubMed | The association between the oral microbiome and oral Kaposi's sarcoma-associated herpesvirus (KSHV) shedding is modified by age and HIV status in a rural Ugandan cohort. | Sabourin, Mugisha, Marshall, Miley, Chen, Billodeaux, Whitby, Rochford, Newton | Journal of oral microbiology | 2026 | Kaposi's sarcoma-associated herpesvirus (KSHV) spreads through saliva. KSHV shedding is intermittent, suggesting individual-level factors affect reactivation.... | Öffnen |
| oral microbiome cancer | PubMed | The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact. | Hajjar, Stephen, Aaroe, Aiche, Al-Zubidi, Ameri, Aragon, Carabenciov, Chambers, Chaudhry, Connors, Davies, Debnath, Faiz, Fuller, Goepfert, Gombos, Gupta, Hadfield, Hutcheson, Islam, Jalal, Jayasekera, Jazieh, Khine, Kim, Lai, Lei, Li, Markovic, McMillan, Moreno, Muhaj, Nader, Otun, Pacha, Palaskas, Patel, Patel, Quandt, Sagiv, Sharon, Shatila, Sheshadri, Suarez-Almazor, Thomas, Wang, Won, Zhang, Naing | Journal of immunotherapy and precision oncology | 2026 | Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet their clinical impact is limited by immune-related adverse events (irAEs), therapeutic resistance, and the lack of reliable predictive biomarkers, contributing to a shift from early promise to a therapeutic plateau. irAEs affec... | Öffnen |
| fusobacterium nucleatum | PubMed | Effects of Probiotics on Oral Microbiological Environment, Gingival Health, and Dental Plaque: A Meta-Analysis. | Kashif, Kazmi, Shah, Qadri | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP | 2026 | This meta-analysis was conducted to assess the effects of probiotics on dental plaque, gingival health, and the oral microbiological environment. PubMed and Google Scholar were searched, and the Cochrane Collaboration's Risk of Bias tool was used to assess the risk of bias in the included studies. T... | Öffnen |
| fusobacterium nucleatum | PubMed | Gut microbiota characteristics of gastric cancer patients across distinct pathological stages and their associations with tumor and paratumor mucosal microbiota. | Qi, Wu, Chen, Zhang, Wang | Frontiers in cellular and infection microbiology | 2026 | Gastric cancer (GC) is closely associated with microbial dysbiosis; however, the spatial-temporal characteristics of the gut, paracancerous, and intratumoral microbiomes, as well as their interrelationships during tumor progression, remain insufficiently defined. This study aimed to characterize the... | Öffnen |
| fusobacterium nucleatum | PubMed | Fusobacterium nucleatum enhances enterotoxigenic Bacteroides fragilis-mediated neuron loss and intestinal motility dysfunction. | Zhang, Zhao, Zhang, Xuan, Wang, Yu, Li, Huang, Zhou, Ning, Ding, Jiang, Hu, Shao, Li, Gao, Chen, Chen, Wang, Cui, Fang, Hong | Nature microbiology | 2026 | Gut dysmotility is a common long-term effect of enterotoxigenic Bacteroides fragilis (ETBF) colonization but the underlying mechanisms are not clear. Here, using mouse colonization models, we found that ETBF-secreted B. fragilis toxin (BFT) causes loss of colonic myenteric neurons, which are crucial... | Öffnen |
| fusobacterium nucleatum | PubMed | Evaluation of Therapeutic and Biopharmaceutical Properties of a Biadhesive Dental Paste Based on a Complex Immunoglobulin Preparation. | Petrulenko, Seifullaeva, Shulakov, Prosycheva, Podporin, Tsarev, Demina, Korol, Alyoshkin, Alyoshkin, Anurova | Bulletin of experimental biology and medicine | 2026 | A topical mucoadhesive dosage form was developed for the treatment of infectious oral cavity diseases, consisting of a paste based on a combination of a complex immunoglobulin preparation (CIP) and interferon alpha-2b. CIP within the final formulation demonstrated robust antimicrobial activity again... | Öffnen |
| fusobacterium nucleatum | PubMed | Clinical translation of gut microbiome biomarkers and host immune dysregulation in colorectal neoplasia: a systematic review with Clinical and Molecular Pathology Prioritisation. | Rangel, Panomket, Panya, Maneenin, Sinthuchao, Seawsakul, Maneenin, Jirapornkul, Wanram | Journal of clinical pathology | 2026 | Gut microbiome signatures are promising non-invasive biomarkers for colorectal neoplasia, but clinical translation is limited by heterogeneity in populations, platforms, validation and comparator tests. We evaluated microbiome-based biomarkers and microbiome-host immune associations, emphasising app... | Öffnen |
| fusobacterium nucleatum | PubMed | Intratumoral microbiota: implications for colorectal cancer pathogenesis and therapy. | Liu, Qi | Frontiers in immunology | 2026 | CRC is the third most prevalent malignancy worldwide and the second leading cause of cancer-related mortality. According to GLOBOCAN 2022 estimates, approximately 1.93 million new CRC cases and 900,000 CRC-related deaths occur annually worldwide. Incidence rates continue to rise in developing countr... | Öffnen |
| fusobacterium nucleatum | PubMed | From Inflamed Gingiva to Invasive Malignancy: Molecular Crosstalk in Oral Carcinogenesis: A Scoping Review. | Jovanova, Angjelova, Campagna, Polizzi, Marya, Isola | Frontiers in bioscience (Landmark edition) | 2026 | Oral squamous cell carcinoma (OSCC) develops within a complex inflammatory microenvironment where chronic mucosal inflammation and microbial dysbiosis may contribute to malignant transformation. Increasing evidence suggests that periodontal pathogens associated with chronic gingival inflammation can... | Öffnen |
| fusobacterium nucleatum | PubMed | Adjunctive Effects of a 2% Zinc Citrate Toothpaste on Plaque and Oral Microbiota in Orthodontic Patients: A Randomized Controlled Trial. | Nguyen, Le, Pham, Pham, Ngo | International journal of dentistry | 2026 | Zinc citrate trihydrate (ZCT) has antibacterial and anti-inflammatory properties and is widely used in oral-care products. However, evidence regarding its effectiveness in orthodontic patients remains limited. This study aimed to evaluate the effects of a toothpaste containing 2% ZCT on gingival inf... | Öffnen |
| bioceramic sealer | PubMed | Effect of Formic Acid and Passive Ultrasonic Irrigation on the Removal of Residual Filling Material Containing AH-Plus Bioceramic Sealer. | Granados-Laura, Liñan-Duran, Garcia-Rupaya | Iranian endodontic journal | 2026 | Root canal retreatment is challenged by the strong adhesion of sealers to dentin. AH-Plus Bioceramic, an epoxy resin-based sealer containing calcium silicate components, could present particular difficulty during removal. This study evaluated whether 5% formic acid with passive ultrasonic activation... | Öffnen |
| bioceramic sealer | PubMed | Resolution of Mental Nerve Paresthesia Associated With a Large Periapical Lesion Following Nonsurgical Endodontic Retreatment: A Case Report With 6-Year Follow-Up. | AbuMostafa | Case reports in dentistry | 2026 | Mental nerve paresthesia of odontogenic origin is an uncommon yet clinically significant presentation. Although malignancy remains the primary concern in the differential diagnosis of lower lip numbness, large periapical lesions of endodontic origin represent an underrecognized but treatable etiolog... | Öffnen |
| bioceramic sealer | PubMed | Short-term radiographic changes of extruded NeoSealer Flo in a simulated enlarged-apex model: influence of moisture and periapical support. | Spinelli, Pergola, Prati, Gandolfi, Zamparini | Clinical oral investigations | 2026 | To radiographically evaluate short-term changes in NeoSealer Flo extruded beyond enlarged apical preparations under different moisture and apical-support conditions.... | Öffnen |
| bioceramic sealer | PubMed | Bioceramic versus conventional endodontic sealers: An umbrella review. | Rayar, Antony, Raghu, Kadandale, Jayakumar, Karunakaran | Journal of conservative dentistry and endodontics | 2026 | Sealers are important to provide hermetic obturation of root canals. Traditional sealers have wide clinical applications but are limited by cytotoxicity, solubility, and biocompatibility. However, bioceramic sealers offer bioactivity, alkaline antibacterial properties, and dentin bonding are the pro... | Öffnen |
| bioceramic sealer | PubMed | Cytotoxicity and Genotoxicity of Newly Formulated Bioceramic Sealers: An In Vitro Study. | Varkalis, Smoczer, Askar, Young, Ferracciolo, Paurazas | Journal of endodontics | 2026 | Bioceramic sealers are used for their favorable biocompatibility, yet concerns remain regarding cytotoxicity and genotoxicity when extruded. Recently introduced sealers, C-Root SP (CSP) and BC Sealer Ion Plus (BCIP), incorporate formulations that enhance bioactivity. This study aimed to evaluate and... | Öffnen |
| bioceramic sealer | PubMed | Comparative Evaluation of Citric Acid, Chlorhexidine, and Their Combination as Root Canal Irrigants on the Push-Out Bond Strength of Resin and Calcium Silicate-Based Sealers to Root Canal Dentin. | Shettigar, Puthen Purayil, Ginjupalli, Ballal | International journal of dentistry | 2026 | Root canal irrigants can alter root canal dentin and influence sealer adhesion. With increasing use of bioceramic sealers, understanding the effects of irrigants on bonding is essential for endodontic success. This in vitro study evaluated the effects of 1% chlorhexidine (CHX), 10% citric acid (CA),... | Öffnen |
| bioceramic sealer | PubMed | Modified Root Canal Sealers: A Comprehensive Review of Bioactive Enhancements, Antimicrobial Strategies, and Physicochemical Performance. | Palose, Thaker, Beskalis, Ali, Singh, Elsayed | Cureus | 2026 | Root canal sealers are essential for achieving a three-dimensional seal of the root canal system, thereby preventing reinfection and facilitating periapical healing. Despite decades of material development, no available sealer satisfies every property expected of an ideal material. This review exami... | Öffnen |
| bioceramic sealer | PubMed | Effect of simvastatin versus calcium hydroxide intracanal medications on postoperative pain and cytokine modulation in symptomatic apical periodontitis: a randomized controlled trial. | Essam Othman Alghidany, Ahmed Morsy, Shaker, Mohamed El Boghdadi | BMC oral health | 2026 | Calcium hydroxide has long been used as an intracanal medicament in endodontics and remains widely applied due to its well-established antimicrobial and anti-inflammatory properties. Owing to its clinical effectiveness, it is recommended for use in a variety of endodontic treatment situations. Simva... | Öffnen |
| bioceramic sealer | PubMed | Storage Stability of Premixed Calcium Silicate-Based Sealers Under Different Temperature and Humidity Conditions. | Kwak, Jo, Sigurdsson, Kim | Materials (Basel, Switzerland) | 2026 | Premixed calcium silicate-based sealers (CSSs) require moisture for hydration and setting, raising concerns regarding the influence of environmental storage conditions on their physicochemical properties. This study evaluated the effects of storage temperature and relative humidity on the flow and s... | Öffnen |
| bioceramic sealer | PubMed | Clinical and radiological outcomes of Thermafil Plus used with bioceramic versus epoxy-resin sealer: results from a 12-month randomized clinical trial. | Spinelli, Zamparini, Lenzi, Pelliccioni, Gandolfi, Prati | Odontology | 2026 | This randomized clinical trial compared the clinical and radiographic outcomes and post-operative pain of a bioceramic-containing sealer (AH Plus Bioceramic) versus an epoxy resin-based sealer (AH Plus) in primary and secondary root canal treatments over 12-month follow-up. A total of 99 permanent t... | Öffnen |
| tricalcium silicate sealer | PubMed | Evaluation of sealing ability and adaptability of different endodontic sealers: | Alhilou, Bakhsh, Alosaimi, Garoot, Alshanqiti, Jaha, Sembawa, Badr | PeerJ | 2026 | Root canal sealers play a critical role in preventing microleakage and ensuring the long-term success of endodontic treatment. AH-Plus is widely considered the gold standard epoxy resin-based sealer, while Bio-C sealer represents a newer premixed bioceramic material with bioactive properties. NanoSe... | Öffnen |
| tricalcium silicate sealer | PubMed | Model-dependent antimicrobial performance of endodontic sealers: An in vitro comparison of planktonic and multispecies biofilm assays. | Raman, Kuehne, Palin, Camilleri | Dental materials : official publication of the Academy of Dental Materials | 2026 | To evaluate the antibacterial effects of tricalcium silicate cement-based sealers and epoxy resin-based sealer with planktonic versus multispecies biofilm assays at 0, 28, and 90 days. The physicochemical properties of the tested sealers were also assessed.... | Öffnen |
| tricalcium silicate sealer | PubMed | Fabrication and characterization of a bioactive glass and tricalcium silicate incorporated resin-based root canal sealer. | Noorani, Mohammed, Nongman, Alawi, Karobari | Journal of conservative dentistry and endodontics | 2026 | To synthesize and characterize an experimental bioactive glass (BG) and tricalcium silicate (TCS) incorporated resin-based root canal sealer and compare its microstructural and elemental characteristics with that of unmodified AH plus and BioRoot RCS.... | Öffnen |
| tricalcium silicate sealer | PubMed | Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers? | Baran, Oncu, Celikten | Australian endodontic journal : the journal of the Australian Society of Endodontology Inc | 2026 | This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser scanning microscopy (CLSM). Eighty single-rooted human teeth... | Öffnen |
| tricalcium silicate sealer | PubMed | Volumetric Stability and Interfacial Adaptation of Tricalcium Silicate-Based Cements Used in the Lid Technique: A Micro-Computed Tomography and Scanning Electron Microscopy Analysis. | Nomura, de Lima Dias-Júnior, Paz Dotto, Barros Steffens, Cavalini Cavenago, da Silveira Teixeira, Tanomaru-Filho, Bortoluzzi, da Fonseca Roberti Garcia | Journal of endodontics | 2026 | This in vitro study evaluated the volumetric stability and interfacial adaptation of tricalcium silicate-based cements with different consistencies (sealer and putty) applied using the Lid technique for retrograde filling in apical surgery.... | Öffnen |
| tricalcium silicate sealer | PubMed | Physicochemical stability of contemporary endodontic sealers with distinct chemical bases under thermal stress: a multi-analytical approach. | Keskin, Turk, Karakullukçu, Khayyati, Nuhoğlu | Odontology | 2026 | The aim of this study was to evaluate the physicochemical stability and clinical handling properties of contemporary root canal sealers with different chemical bases (hydraulic calcium silicate, resin, and silicone-based) under thermal stress simulating warm vertical compaction (WVC) using a multi-a... | Öffnen |
| tricalcium silicate sealer | PubMed | Nonsurgical Endodontic Management of Oehler's Type II | Laporte, Mancino, Minoux | Clinical case reports | 2026 | Kein Abstract... | Öffnen |
| tricalcium silicate sealer | PubMed | Analysis of the long-term solubility and phases of five different root canal sealers in phosphate buffered saline: an | Jalan, Shetty, Kumblekar, M, Shetty | PeerJ | 2026 | The long-term success of root canal therapy depends substantially on the physicochemical stability of endodontic sealers, particularly their solubility and the development of stable crystalline phases during setting. Tricalcium silicate-based sealers (TSBSs) have shown promising biological propertie... | Öffnen |
| tricalcium silicate sealer | PubMed | Comparative finite element analysis of internal root resorption treatment using various root canal filling materials. | Karaağaç Eskibağlar, Erdem, Eskibağlar, Kaman | BMC oral health | 2026 | BACKGROUND: This study evaluated the stress distribution in maxillary incisors with internal resorption (IR) filled with various root canal filling materials using finite element analysis (FEA). METHODS: A three-dimensional model of the maxillary central incisor was generated by scanning. Twenty-sev... | Öffnen |
| tricalcium silicate sealer | PubMed | Evaluation of tissue response of experimental calcium silicate-based endodontic sealers: An in vivo study. | Silva, Rodrigues, Sasso-Cerri, Tanomaru-Filho, Guerreiro-Tanomaru, Cerri | European journal of oral sciences | 2026 | The aim of this study was to evaluate whether the experimental sealers, composed of tricalcium silicate (CaSi) and CaSi supplemented with calcium hypochlorite (CaSi-H), stimulate tissue repair. The tissue response of experimental materials was compared with commercially available materials Bio-C sea... | Öffnen |
| 3D printed zirconia implants | PubMed | 3D-printing for zirconia abutment manufacturing and screw access hole effect: fatigue behavior of milled zirconia simplified restorations. | Cocco, Teixeira, de Freitas Daudt, Pozzebon, Kleverlaan, Tribst, Soares, Pereira, Valandro | Odontology | 2026 | The aim of this study is to evaluate the effect of the abutment manufacturing method (CAD/CAM milling or 3D-printing) and the presence of a screw access hole on the fatigue behavior of adhesively cemented zirconia restorations. Zirconia (3YSZ) discs, representing prosthetic abutments (Ø= 10 mm, 3 mm... | Öffnen |
| 3D printed zirconia implants | PubMed | Accuracy of the Emergence Profile of Dental Implant Restorations using different gingival mask techniques. | Farhan, Abdul Sahib, Jassim, Khalaf, Fatalla | Journal of clinical and experimental dentistry | 2026 | Accurate reproduction of peri-implant soft tissue contours is essential for the esthetics, phonetics, hygiene, and long-term success of implant-supported restorations. Gingival mask (GM) techniques play an important role in reproducing the emergence profile (EP) and peri-implant soft tissue contour.... | Öffnen |
| 3D printed zirconia implants | PubMed | Prosthesis-Based 3D Guide System for Maxillary Implant Placement: A Feasibility Study Using a Split-Mouth Evaluation. | Tudts, Moodley, D'haese, Vandeweghe | Dentistry journal | 2026 | Kein Abstract... | Öffnen |
| 3D printed zirconia implants | PubMed | Wear resistance of 3D-printed and milled denture teeth materials for complete-arch implant-supported prostheses: An in vitro study. | Sanchez, Lawand, Bazarbashi, Jreige, Marrano, Martin, Gonzaga, Rocha | Journal of prosthodontics : official journal of the American College of Prosthodontists | 2026 | The purpose of this in vitro study was to compare the two-body wear resistance of milled and 3D-printed denture teeth against various CAD-CAM prosthetic materials.... | Öffnen |
| 3D printed zirconia implants | PubMed | Managing An Unexpected Cemento-Dentinal Tear with a 3D-printed Crown Generated Chairside: A Case Report with 2 years Follow Up. | Azpiazu-Flores, Saponaro, Lin, Morton, Zandoná, Azer | The International journal of prosthodontics | 2026 | A 65-year-old Caucasian female was seen for the treatment of a failing mandibular fixed dental prosthesis (FDP). When the abutment teeth were evaluated, tooth 44 had an extensive carious lesion and was determined non-restorable, and tooth 47 was deemed salvageable. The patient presented and accepted... | Öffnen |
| 3D printed zirconia implants | PubMed | Implementing 3D-printed indexing devices and contemporary scanning techniques for complete-arch implant-supported rehabilitations: A clinical case report. | Azpiazu-Flores, Phuckdeedindan, Aldosari, Yang, Morton, Lin | Journal of prosthodontics : official journal of the American College of Prosthodontists | 2026 | A sixty-eight-year-old male presented to the dental clinic seeking a complete mouth rehabilitation. He exhibited generalized dental caries, dental staining, cervical lesions, fremitus, and anterior wear. After declining tooth-retaining options, he elected full-mouth extractions with immediately load... | Öffnen |
| 3D printed zirconia implants | PubMed | Zirconia in dentistry: A 25-year bibliometric analysis of research trends, thematic evolution, and emerging frontiers. | Zhang, Chen, Wu, Miao, Luo | Journal of dentistry | 2026 | This bibliometric analysis aimed to map the global research landscape of zirconia in dentistry over the past 25 years, focusing on publication output, collaboration patterns, thematic evolution, and emerging research fronts.... | Öffnen |
| 3D printed zirconia implants | PubMed | Mechanical, translucency, tribological resistance, and biocompatibility of lithium disilicate glass-ceramics produced by ZrO | Xia, Tong, Zhou, Ye, Xu, Feng, Zhu, Chen, Li, Lin, Wen, Ma | Dental materials : official publication of the Academy of Dental Materials | 2026 | Lithium disilicate glass-ceramics (LDGCs) have become one of the most widely used dental prosthesis materials in clinical practice due to their excellent esthetics, biocompatibility, and enamel-like wear resistance. However, their inherent brittleness, limited mechanical strength, and progressive we... | Öffnen |
| 3D printed zirconia implants | PubMed | Evaluation of marginal and internal adaptation of implant-supported PEEK crowns fabricated by 3D printing, milling, and pressing: a micro-CT analysis. | Mahrous, El-Shazly, Mansour, Shabaan, Mokhtar, Tawfik, Radwan | BMC oral health | 2026 | OBJECTIVES: This study aimed to evaluate and compare the marginal adaptation and internal gap of implant-supported crowns fabricated from polyetheretherketone (PEEK) using CAD-CAM milling, heat pressing, and 3D printing, employing non-destructive micro-computed tomography (µCT). METHODS: This in-vit... | Öffnen |
| additive manufacturing zirconia | PubMed | Evaluation of full-veneer crowns fabricated with 3D printing resin material for definitive prostheses: A 1-year randomized controlled prospective study. | Shin, Oh, Kim | Journal of dentistry | 2026 | To compare the 1-year clinical performance of definitive 3D-printed resin crowns (RCs) and monolithic zirconia crowns (ZCs) used as tooth-supported posterior single crowns.... | Öffnen |
| additive manufacturing zirconia | PubMed | Effect of Manufacturing Technique and Cementation Protocol on the Load-Bearing Capacity of 3D-Printed Zirconia Molar Crowns. | Oßwald, Schwindling, Rues, Rosentritt, Haas, Rauch | Bioengineering (Basel, Switzerland) | 2026 | This study evaluated the influence of the manufacturing method and cementation protocol on the fracture load of zirconia molar crowns. A total of 32 full-contour crowns with a wall thickness of 1 mm were fabricated from 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP). Sixteen crown... | Öffnen |
| additive manufacturing zirconia | PubMed | Effects of build orientation and manufacturing system characteristics in digital light processing additive manufacturing on the properties of zirconia. | Cho, Park, Jang, Chung, Eyüboğlu, Özcan | Journal of the mechanical behavior of biomedical materials | 2026 | To evaluate the influence of build orientation and manufacturing system characteristics in digital light processing (DLP) additive manufacturing on the surface roughness, internal structure, and biaxial flexural strength of 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP).... | Öffnen |
| additive manufacturing zirconia | PubMed | Three-Dimensional Printed Materials for Definitive Ceramic and Resin Restorations: A Scoping Review. | Rachiotis, Pachiou, Salem, Karasan, Sailer, Rahiotis | Materials (Basel, Switzerland) | 2026 | The integration of additive manufacturing (AM) into digital dentistry has extended 3D printing beyond auxiliary applications toward the fabrication of definitive restorations, yet the evidence remains dispersed across diverse materials and technologies. This scoping review aimed to map the available... | Öffnen |
| additive manufacturing zirconia | PubMed | From milling to printing: evaluating the applicability of zirconia in restorative dentistry. | Yoo, Kim, Koak, Park | The journal of advanced prosthodontics | 2026 | This study compared the mechanical and optical properties of 3D-printed and milled zirconia, and evaluate the marginal and internal adaptation of crowns fabricated with 3Y-TZP and veneers fabricated with 5Y-TZP.... | Öffnen |
| additive manufacturing zirconia | PubMed | Publication trends and knowledge structure of the Journal of Advanced Prosthodontics: A bibliometric analysis from 2009 to 2025. | Han, Moon, Shim, Kim, Kim | The journal of advanced prosthodontics | 2026 | This bibliometric study evaluated the publication output, citation performance, contributor characteristics, thematic structure, and cited knowledge base of the Journal of Advanced Prosthodontics from 2009 to 2025.... | Öffnen |
| additive manufacturing zirconia | PubMed | Three-Dimensional Evaluation of Marginal Gap in Prefabricated Zirconia and 3D-Printed Pediatric Crowns. | Karaağaç Eskibağlar, İpek, Rençber Kızılkaya | Materials (Basel, Switzerland) | 2026 | Kein Abstract... | Öffnen |
| additive manufacturing zirconia | PubMed | Comparison of Fracture Resistance of 3D Printed and Milled Zirconia Veneers and Anterior Crowns. | Kalman, Alhothan, Ghavami-Lahiji, Tsujimoto | Clinical and experimental dental research | 2026 | It has recently become possible to prepare monolithic zirconia restorations through 3D printing, in addition to the typical milling technique. In this study, the fracture resistance of anterior crowns and veneers prepared by both techniques was compared.... | Öffnen |
| AI endodontics | PubMed | Dicer-independent miR-451a is upregulated in periodontitis and potentiates inflammation by impairing macrophage polarization and SOCS activity. | Naqvi, Maddalozzo, Amin, Capistrano, Valverde, Rahat, Siddiqui, Li, Wu, Zhang, Pettiette, Moretti, Singh, Nares, Naqvi | Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 2026 | Periodontitis (PD) is characterized by localized inflammatory tissue destruction, yet the lesion-associated microRNA (miRNA)networks that regulate host immune responses remain incompletely defined. In this study, we aimed to identify and characterize dysregulated gingivalmiRNAs in PD that modulate i... | Öffnen |
| AI endodontics | PubMed | Biomechanical effects of cavity preparation and restorative procedures on strain and bite force distribution in posterior teeth: a systematic review of experimental studies. | Sahoo, Grinath, Menon, Sreeya, Julie Minerva | Odontology | 2026 | To systematically evaluate the biomechanical effects of cavity preparation and restorative procedures on cuspal strain, deflection, and load distribution in posterior teeth, while critically appraising methodological quality in experimental and computational models. This systematic review followed P... | Öffnen |
| AI endodontics | PubMed | Pulpotec® Beyond Pulpotomy: A Case Series of Versatile Applications in Vital Pulp Therapy Procedures in Permanent Teeth. | Pattnaik, Sharma, Kusuma, Chauhan, Shah, Singh Dhull, Surana | Cureus | 2026 | Vital pulp therapy is a conservative approach aimed at preserving pulp vitality in teeth affected by deep caries or pulp exposure. Pulpotec® has been widely used as a pulpotomy medicament in primary teeth; however, its application in permanent teeth remains limited. This case series illustrates the ... | Öffnen |
| AI endodontics | PubMed | Portable Deep Learning-Assisted Device for Automated Interincisal Opening Assessment and Oral Submucous Fibrosis Lesion Identification: A Translational Clinical Study. | Bora, Tamhankar, Wankhede, Nagpure, Rathod, Datarkar, Mahore, Jadhav, Dhoke, Lodhi, Sharma, Lanjekar, Kasliwal, Patel, Mandal | Journal of imaging informatics in medicine | 2026 | Oral submucous fibrosis (OSMF) is a chronic, progressive, potentially malignant disorder prevalent in Southeast Asia and the Indian subcontinent. Progressive fibrosis restricts mouth opening, making interincisal opening as a key parameter of disease staging. This study developed a portable AI-based ... | Öffnen |
| AI endodontics | PubMed | Design, Synthesis, In Silico Studies, and HIV-1 RT Inhibitory Activity of 1,3-Oxazolidine Pyrimidine Nucleoside Analogues. | Sriharsha, Mohamed, Mahmood, Sangi, Shaik, Nagaraja, Kumari, Thirunavukkarasu, Sreenivasalu, Islam, Chohan, Biradar | Chemistry & biodiversity | 2026 | A series of 1,3-oxazolidine nucleoside analogues (1-6) was designed and synthesized for their anti-HIV activity. The purpose of this study was to determine whether the antiviral activity of the pyrimidine ring is affected by oxazolidine ring substitution. The synthesized compounds were tested for th... | Öffnen |
| AI endodontics | PubMed | Personalized brain-based anesthetic-state detection with portable fNIRS and AI. | Minoccheri, Joo, Hu, Affendi, Elayyan, Harville, McDonald, Botero, DaSilva | Brain research bulletin | 2026 | Portable functional near-infrared spectroscopy (fNIRS) may support brain-based monitoring around local anesthesia, but between-patient variability and patient-overlapping validation can limit generalization. We examined affected-tooth classification before versus after anesthesia, exploratory Pre-se... | Öffnen |
| AI endodontics | PubMed | Readiness of Dental Professionals to Adopt Artificial Intelligence for Cone-Beam Computed Tomography Interpretation: A Cross-Sectional Survey. | Chauhan, Roy, Khan, Palwankar, Adwani, Singh | Cureus | 2026 | Artificial intelligence (AI) is being increasingly incorporated into cone-beam computed tomography (CBCT) interpretation to support diagnostic accuracy and clinical decision-making. However, successful implementation depends on the readiness and acceptance of the dental professionals. This study aim... | Öffnen |
| AI endodontics | PubMed | Clinical and Epidemiological Characteristics of Retrospective Single-Center Observational Study. | Andrei, Liliac, Boldeanu, Busuioc, Pătru, Țuculina, Bușu, Iacov, Pătru, Munteanu | Journal of clinical medicine | 2026 | Kein Abstract... | Öffnen |
| AI endodontics | PubMed | Accuracy and Short-Term Consistency of Generative AI Chatbots in Guideline-Based Endodontic Decision Support: A Multi-Model Benchmarking Study. | İlgenli, Avcı, Köse | Dentistry journal | 2026 | Kein Abstract... | Öffnen |
| artificial intelligence dentistry | PubMed | Harnessing Artificial Intelligence to Restore Standards in Medical and Dental Education in Pakistan. | Bashir, Abbas, Ashraf | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP | 2026 | Pakistan's medical and dental education has experienced declining standards, inconsistent regulation, and periodic loss of degree recognition. This viewpoint proposes a structured role for artificial intelligence (AI) to analyse past failures and to guide prospective reforms. As medical education gl... | Öffnen |
| artificial intelligence dentistry | PubMed | State-of-the-art deep learning for dental implant detection: a standardized benchmark for clinical practice. | Kang, Kim, Chaurasia, Lee | Journal of periodontal & implant science | 2026 | Although deep-learning approaches show promise for detecting dental implants, the absence of standardized benchmarks has hindered evidence-based model selection. This study systematically compared five contemporary architectures on the same dataset under controlled conditions. A three-seed training-... | Öffnen |
| artificial intelligence dentistry | PubMed | Real-Time Intelligent Coaching Versus Human Expert Instruction in Surgical Skills Training: A Systematic Review and Meta-Analysis. | Askari Shah, Mashayekhi, Reji, Nawaz, Rehman, Kumar, Odedara, Khalfan Alkaabi, Kang, Abdulrahem Mousa, Muhammad Ali, Qazi | Cureus | 2026 | Real-time intelligent coaching systems are technology-based surgical training tools that provide automated, real-time, and objective feedback on learners' performance during simulated surgical tasks. Unlike human expert instruction, which relies on instructor-delivered guidance and feedback, these s... | Öffnen |
| artificial intelligence dentistry | PubMed | Integrating resting-state functional connectivity, mismatch negativity, and auditory steady-state responses reveals convergent neurophysiological biomarkers of schizophrenia. | Abdullah, Hameed, Baig, Nematov, Sapaev, Ismail, Bani Younes, Arora, Sharma, Mohammadi, Khasawneh | Cognitive neurodynamics | 2026 | Schizophrenia is a heterogeneous neuropsychiatric disorder characterized by abnormalities in large-scale brain connectivity, auditory prediction-error processing, and cortical gamma-band synchronization. Although resting-state electroencephalography (EEG), mismatch negativity (MMN), and auditory ste... | Öffnen |
| artificial intelligence dentistry | PubMed | Age estimation through mandibular radiomic attributes in panoramic radiographs using convolutional neural networks. | de Sousa, Silva, Borella, Dos Anjos Pontual, Paulino, Bento, de Melo | Imaging science in dentistry | 2026 | Artificial intelligence (AI)-based approaches to mandibular age estimation are limited by reliance on manually selected anatomical features. Thus, this study aimed to develop and validate a convolutional neural network (CNN)-based model to estimate age from panoramic radiographs through the analysis... | Öffnen |
| artificial intelligence dentistry | PubMed | Reliability of the QUADAS-2 checklist in AI-based medical imaging: A comparison of human reviewers and ChatGPT-4o. | Dashti, Khosraviani, Ghadimi, Kalantari, Amirzade-Iranaq, Hemmati, Arzani, Pirayesh, Motie | Imaging science in dentistry | 2026 | Artificial intelligence is reshaping medical imaging, yet reliable bias assessment in this context remains insufficiently studied. It remains unclear whether the widely used QUADAS-2 checklist provides reproducible evaluations in AI-based imaging studies. Therefore, we compared human and ChatGPT-4o ... | Öffnen |
| cavitational osteonecrosis | PubMed | Could Silent Inflammation Originating in Jawbone Cavitations Play a Role in Activating the CCL5/CCR5 Axis in Female Breast Cancer? A Diagnostic and Therapeutic Gap in Osteoimmunological Interactions. | Vasconcelos E Cruz, Perko, Doebis, Notter, Schick, Lechner | OncoTargets and therapy | 2025 | Breast cancer (BC) is one of the leading causes of cancer mortality worldwide. The chemokine CCL5 and its receptor CCR5 have been demonstrated to be associated with tumour progression, immune evasion, and metastasis.... | Öffnen |
| cavitational osteonecrosis | PubMed | Neuralgia Inducing Cavitational Osteonecrosis of the Jaw: Scientific Controversy or pseudoscience? | Keith | Journal of pain research | 2025 | Jawbone cavities have had a long history in dentistry and for many years they have been described and studied under several different pseudonyms. These cavities are thought to be responsible for a wide range of disease processes and symptoms, including orofacial neuralgia. In this article the existe... | Öffnen |
| cavitational osteonecrosis | PubMed | Quantitative Real-Time RT-PCR Verifying Gene Expression Profile of Cavitations Within Human Jaw Bone. | Ghanaati, Dohle, Schick, Lechner | Biomedicines | 2025 | Kein Abstract... | Öffnen |
| RANTES CCL5 dentistry | PubMed | Insights into the Anti-Inflammatory Effects of Soft Tissue Manipulation. | Lowery, Mustaklem, Wakefield, Brown, Sasse, Baule, Street, Pradhan, Sandhu, Marciano, Eland, Loghmani, Chu | Biology | 2025 | Soft tissue manipulation (STM) is widely used by physical therapists, massage therapists, athletic trainers, and osteopathic physicians to manage musculoskeletal pain, yet its biological mechanisms remain poorly understood. Preclinical studies indicate that STM can alter immune cell behavior in anim... | Öffnen |
| focal infection theory dentistry | PubMed | C. Edmund Kells' "High Spots on the Road in Root Canal Treatment:" Historical & Contemporary Perspectives on his 1926 dictates. | Manjarrés, Méndez, Gutmann | Journal of the history of dentistry | 2025 | Kein Abstract... | Öffnen |
| root canal cancer correlation | PubMed | Evaluation of three obturation techniques in 3D-printed models of oval canals with standardized prepared morphology: a micro-CT study. | Xia, Gu, Song, Liu, Deng, Qian | BMC oral health | 2025 | The complex and irregular morphology of prepared oval root canals poses optimal sealing in oval canals as a key endodontic challenge. To address this, this study utilized five types of standardized 3D-printed models replicating prepared anatomy of extracted teeth with oval canal, to characterize the... | Öffnen |
| root canal cancer correlation | PubMed | A clinical study on the preservation of pulp sensitivity in affected teeth with jaw cysts using concentrated growth factor: a retrospective Cross-sectional study. | Zhou, Mao, Shi, Lu, Lai, Wang, Li, Chen | Scientific reports | 2025 | Jaw cysts commonly affect the oral and maxillofacial region. This study aimed to evaluate the effect of Concentrated Growth Factor (CGF) application during jaw cyst surgery on postoperative pulp sensitivity changes in affected teeth. This retrospective cross-sectional study included fifty-one patien... | Öffnen |
| root canal cancer correlation | PubMed | Radicular Cysts and Periapical Granulomas: Data Documentation for 696 Cases and Findings on Fibrosis, and Porphyromonas gingivalis and Fusobacterium nucleatum in These Lesions. | Virkkunen, Kaarela, Laine, Suominen, Hagström, Sorsa, Haglund | Clinical and experimental dental research | 2025 | The objective of our study was to re-evaluate periapical lesions, including radicular cysts (RCs) and periapical granulomas (PGs) for locations, histopathological features, and degree of fibrosis in relation to the inflammatory response. In addition, we examined the presence of Porphyromonas gingiva... | Öffnen |
| root canal cancer correlation | PubMed | Metastatic Status and Dissection Effect of Regional/Extraregional Lymph Nodes in Japanese Patients with Squamous Cell Carcinoma of the Anal Canal: A Multicenter Retrospective Cohort Study. | Torigoe, Hirata, Yamada, Ajioka, Sugihara | Journal of the anus, rectum and colon | 2025 | Squamous cell carcinoma of the anal canal (SCCA) is a rare condition. Standard treatment includes chemoradiotherapy, with surgical treatment reserved for limited cases. In the future, the decrease in surgical frequency makes it more difficult to pathologically assess the depth of tumor invasion and ... | Öffnen |
| ceramic dental implants | PubMed | A Case Report of Interdisciplinary Prosthodontic Rehabilitation and Voice Restoration in a Diabetic Professional Singer with Complex Dental Failure. | Srinivas, Pillai, Ganesh, Doddawad, Raghavendra Swamy, Rudraswamy | Journal of International Society of Preventive & Community Dentistry | 2024 | Dental pathology in professional singers can compromise the oral resonance chamber, jeopardizing their vocal performance and career longevity. Complex cases involving systemic diseases, psychological distress, and advanced oral deterioration require integrated multidisciplinary management. This repo... | Öffnen |
| cavitational osteonecrosis | PubMed | Comparison of Cytokine RANTES/CCL5 Inflammation in Apical Periodontitis and in Jawbone Cavitations - Retrospective Clinical Study. | Vasconcelos E Cruz, Notter, Schick, Lechner | Journal of inflammation research | 2024 | Apical periodontitis (AP) is one of the most common endodontic diseases associated with osteo destructive cytokine production. The literature also reports cytokine studies in fatty degenerative osteonecrotic bone marrow defects (BMDJ/FDOJ) independent of AP.... | Öffnen |
| focal infection theory dentistry | PubMed | Update on Focal Infection Management: A Czech Interdisciplinary Consensus. | Peřina, Šmucler, Němec, Barták | International dental journal | 2024 | The focal infection theory has been used to explain several chronic systemic diseases in the past. Systemic diseases were thought to be caused by focal infections, such as caries and periodontal diseases, and dentists were held responsible for these diseases due to the spread of oral infections. As ... | Öffnen |
| root canal cancer correlation | PubMed | Macrophage polarization in human periapical lesions in relation to histopathological diagnosis, clinical features and lesion volume: An ex vivo study. | Visarnta, Ratisoontorn, Panichuttra, Sinpitaksakul, Chantarangsu, Dhanuthai | International endodontic journal | 2024 | To evaluate M1 and M2 macrophage polarization in radicular cysts and periapical granulomas through an immunohistochemical analysis and the correlation between macrophage polarization and histopathological diagnosis, clinical characteristics and lesion volume using cone-beam computed tomography.... | Öffnen |
| root canal cancer correlation | PubMed | Geo-spatial epidemiology of gallbladder cancer in Bihar, India. | Sakamoto, Kumar, Choudhary, Bishwapriya, Ghosh | The Science of the total environment | 2024 | Recently, a substantial increase in gallbladder cancer (GBC) cases has been reported in Bihar, India. The region's groundwater can naturally contain harmful concentrations of arsenic, which appears to be epidemiologically linked to the unusually high incidence. However, the root causes remain largel... | Öffnen |
| root canal cancer correlation | PubMed | Expert consensus on difficulty assessment of endodontic therapy. | Huang, Wang, Liang, Ling, Bian, Yu, Hou, Chen, Li, Ye, Cheng, Xu, Hu, Wu, Guo, Su, Chen, Qiu, Chen, Wei, Huang, Yu, Lin, Zhang, Yang, Zhao, Pan, Yang, Wu, Pan, Xie, Deng, Huang, Zhang, Yue, Zhou | International journal of oral science | 2024 | Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and preven... | Öffnen |
| root canal cancer correlation | PubMed | A Case of Respiratory Epithelium-Lined Cyst with Enriched Nociceptor Innervation. | Diogenes | Journal of endodontics | 2024 | Apical lesions of endodontic origin can be classified as either granulomas or cysts. In rare cases, respiratory epithelium can proliferate and encapsulate a lesion, forming a cyst. Moreover, the innervation of apical lesions has only been previously reported in animal models of apical periodontitis.... | Öffnen |
| cavitational osteonecrosis | PubMed | Response to the letters to the editor: Neuralgia-inducing cavitational osteonecrosis-A systematic review. | Sekundo, Wiltfang, Schliephake, Al-Nawas, Rückschloß, Moratin, Hoffmann, Ristow | Oral diseases | 2022 | Kein Abstract... | Öffnen |
| cavitational osteonecrosis | PubMed | When systematic reviews are not done by experts. | Bouquot | Oral diseases | 2022 | Kein Abstract... | Öffnen |
| cavitational osteonecrosis | PubMed | Neuralgia-inducing cavitational osteonecrosis - A systematic review. | Sekundo, Wiltfang, Schliephake, Al-Nawas, Rückschloß, Moratin, Hoffmann, Ristow | Oral diseases | 2022 | To assess the aetiologic factors, proposed diagnostic means and treatment strategies for neuralgia-inducing cavitational osteonecrosis.... | Öffnen |
| focal infection theory dentistry | PubMed | Association between Endodontic Infection, Its Treatment and Systemic Health: A Narrative Review. | Niazi, Bakhsh | Medicina (Kaunas, Lithuania) | 2022 | The 'Focal Infection Era in Dentistry' in the late 19th and early 20th century resulted in widespread implementation of tooth extraction and limited the progress of endodontics. The theory proposed that bacteria and toxins entrapped in dentinal tubules could disseminate systemically to remote body p... | Öffnen |