Aktuelle Studien – Biologische Zahnmedizin

Automatisch aktualisiert mehrmals pro Woche | Stand: | 213 Einträge

Keyword Quelle Titel Autoren Journal Datum Abstract (Auszug) Link
integrative dentistry PubMed Navigating Trifurcated Root Anatomy in Maxillary Premolars: A Detailed Endodontic Case Series. Kuzhanchinathan, Doraiswamy, Rajendran Case reports in dentistry 2026 A foundational grasp of root canal anatomy is vital for achieving predictable treatment and long-term outcomes in endodontics. Untreated canal is the primary cause of persistent apical periodontitis following endodontic therapy. Maxillary premolars with three roots and canals exhibit a rare but clin... Öffnen
apical periodontitis PubMed Autologous Dental Pulp Stem Cell Transplantation for Mature Teeth With Apical Periodontitis and Root Perforation: Clinical and Radiographic Outcomes in Two Cases. Matsuki Case reports in dentistry 2026 This case report is aimed at evaluate the feasibility of regenerative endodontic therapy (RET) using autologous dental pulp stem cells (DPSCs) for previously endodontically treated, nonvital mature teeth with apical periodontitis and root perforation.... Öffnen
endodontic treatment PubMed Internal root resorption: understanding the pink tooth of mummery and its clinical implications. Mercante, Nunes, Alves de Toledo, Duarte Seixas Sostena, Nunes, Gonçalves, Martins, Miranda Vieira Journal of clinical and experimental dentistry 2026 Root resorption may be physiological or pathological. Physiological resorption occurs in deciduous teeth to allow replacement by permanent successors. In permanent dentition, resorption is pathological and classified as external (ERR) or internal (IRR), depending on its origin. IRR begins within the... Öffnen
endodontic treatment PubMed Bioactivity and dimensional stability of resin-, hybrid-, and silicate-based endodontic sealers: An in vitro comparative study. Dias, Freitas Furtado, Ferreira Damasceno, de Carvalho, Gondim, Alcalde, Húngaro Duarte, de Vasconcelos Journal of clinical and experimental dentistry 2026 The success of endodontic treatment depends on selecting sealers with suitable physicochemical and biological properties. Solubility, pH, and calcium ion (Ca²+) release are critical factors influencing biocompatibility, antimicrobial activity, and long-term sealing.... Öffnen
endodontic treatment PubMed Effect of Pre-emptive Injection-based Corticosteroid Administration and Its Routes on Post-Endodontic Pain: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Al-Yamoor, Stefanescu, Iuga, Espada-Salgado, Bilsborrow, Teja, Vasundhara Journal of clinical and experimental dentistry 2026 Post-endodontic pain PP is a frequent complication following root canal treatment RCT, primarily resulting from acute inflammation. Pre-emptive corticosteroid administration has been proposed to attenuate this inflammatory response and reduce PP. This systematic review and meta-analysis assessed the... Öffnen
endodontic treatment PubMed Effect of Apical Third Enlargement to Different Preparation Sizes and Tapers on Postoperative Pain and Intra-canal Bacterial Reduction: A Randomized Clinical Trial. Abbas, Hussein Diab, Abd-El Baky, Morsy Journal of clinical and experimental dentistry 2026 Apical preparation size plays a vital role in root canal instrumentation, yet the ideal size and taper remain a subject of debate. This randomized clinical trial was designed to assess the influence of different apical preparation sizes and tapers on postoperative pain and intracanal bacterial reduc... Öffnen
bioceramic sealer PubMed Adverse tissue reaction to a next-generation bioceramic sealer: a structured literature review and case report. Ceraulo, Barbarisi, Hu, Migliore, Lauritano, Caccianiga, Carinci Frontiers in dental medicine 2026 Calcium silicate-based (bioceramic) sealers are widely used in endodontics due to their favorable biological properties and high clinical success rates. Although apical extrusion is generally considered well tolerated, cases of adverse tissue reactions have been reported. The aim of this study was t... Öffnen
endodontic treatment PubMed Partial restoration of fracture resistance in mandibular molars: A comparative study of Bio MTA+ and calcium-enriched mixture for furcal perforation repair. Ozasir, Ozasir, Imamoglu, Rahimi, Gulsahi Journal of applied biomaterials & functional materials 2026 ObjectiveFurcal perforations are iatrogenic complications which compromise the biological and mechanical integrity of endodontically treated teeth. Although calcium silicate-based materials are widely used for perforation repair, their ability to restore fracture resistance remains unclear. This stu... Öffnen
root canal treatment PubMed Long-term survival of primary root canal treatment in teeth restored with indirect cuspal coverage restorations: a 10-year retrospective study. Haupt, Mielke, Hausdörfer, Wiegand, Kanzow Journal of endodontics 2026 This study aimed to evaluate the long-term survival of primary root canal treatment in posterior teeth restored with indirect cuspal coverage restorations.... Öffnen
root canal treatment PubMed Histological evaluation of energy-intensive irrigation systems for debridement of uninstrumented oval root canals with different access cavity designs. Özdemir, Gündoğar, Özyürek, Bolat, Gündoğar, Kaşıkçı, Haapasalo Lasers in medical science 2026 This study aimed to evaluate the effectiveness of energy-intensive irrigation activation systems for removing residual pulp tissue in completely uninstrumented oval root canals with different access cavity designs, using histological analysis. Seventy extracted human mandibular premolars with oval r... Öffnen
endodontic treatment PubMed Management of odontogenic sinusitis related to dental implants and maxillary sinus grafting: a retrospective single-center study. Sabatino, Lopez, Mattaroccia, Valentini, Iafrati, De Benedetto, Moffa, Casale Frontiers in surgery 2026 The increasing use of dental implants is changing the epidemiology of Odontogenic Sinusitis (ODS). Aside from endodontic causes, we frequently encounter problems caused by implant placement and bone augmentation techniques, which present a distinct pathophysiological profile compared to classic ODS.... Öffnen
endodontic treatment PubMed Postoperative Pain and Matrix Metalloproteinase-9 Pulpal Blood Level in Symptomatic Pulpitis of Mature Molars Treated with Biodentine and Portland Cement Full Pulpotomy: A Randomized Clinical Trial. Youssef-Gamal, Sadek, Hilaly Mohamed Eid Journal of clinical and experimental dentistry 2026 This study compared postoperative pain after Biodentine and Portland cement full pulpotomy in mature molars with symptomatic pulpitis. Additionally, it correlated the pulpal blood level of Matrix Metalloproteinases-9 MMP-9; as a marker of the state of pulp inflammation, with the preoperative pain sc... Öffnen
apical periodontitis PubMed Antibiotics After Non-Surgical Root Canals: National Dental Practice-Based Research Network Findings. Law, Nguyen, Funkhouser, Mungia, Nixdorf, Lam, Gilbert Journal of dentistry 2026 Despite guideline recommendations discouraging routine antibiotic use for localized endodontic infections, antibiotics continue to be prescribed after non-surgical root canal therapy (RCT). This study evaluated antibiotic prescribing patterns among general dentists and endodontists across a range of... Öffnen
AI endodontics PubMed Performance of large language models on undergraduate endodontic multiple-choice questions. Sümbüllü, Ünal, Menteş, Kayahan BMC oral health 2026 This study aimed to evaluate the accuracy and consistency of responses provided by three large language models (LLMs), ChatGPT-5.2, Gemini-3, and DeepSeek-V3.2, to multiple-choice questions based on undergraduate endodontic education, asked on different days and at different times of the day.... Öffnen
apical periodontitis PubMed The relationship of apical periodontitis with chronic diseases and smoking habits: an umbrella review. Alshehri, Alshail, AlQwizany, Almalik, Alshahrani, Asiri, AlQahtani, Alshehri, Al-Hawwas Odontology 2026 Growing evidence suggests a potential association between apical periodontitis (AP), chronic diseases, and smoking habits. However, findings from individual studies and systematic reviews remain fragmented, and high-level synthesis of available meta-analyses is limited. This umbrella review aimed to... Öffnen
apical periodontitis PubMed Occult odontogenic infection as a possible trigger of post-streptococcal glomerulonephritis: a case report and scoping review highlighting a possible oral-systemic association. Signorelli, Moura, Ferraz, Dos Reis, Machado BMC oral health 2026 Chronic odontogenic infections may represent overlooked infectious foci in patients with infection-related glomerulonephritis when conventional sources, such as skin or upper respiratory tract infections, are not identified. This manuscript first reports the case of a 36-year-old man who presented w... Öffnen
apical periodontitis PubMed Ferroptosis in the pathogenesis and therapeutic target of oral infectious diseases: A narrative review. Li, Huang, Zhang, Mao, Feng, Zhao, Jiang Archives of oral biology 2026 This review summarizes the major metabolic processes underlying ferroptosis, elucidates its interaction mechanisms with oral infectious diseases, and outlines potential therapeutic targets for ferroptosis in oral infections, aiming to inform future treatment approaches.... Öffnen
apical periodontitis PubMed Intraoperative Identification of Vital Radicular Pulp in a Tooth Diagnosed with Pulp Necrosis: Four-Year Outcome of Tampon Pulpotomy. Asgary Iranian endodontic journal 2026 Teeth diagnosed clinically with pulp necrosis and apical periodontitis may occasionally retain vital radicular pulp tissue despite negative sensibility test responses. Such diagnostic discrepancies highlight the limitations of conventional pulp testing and may create opportunities for biologically b... Öffnen
apical periodontitis PubMed Metformin suppresses periapical bone resorption in a mouse model of apical periodontitis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro. Alghamdi, Ren, Tazawa, Liu, Zhou, Takahashi, Ishidori, Ohshima, Kawashima, Okiji, Yahata Journal of oral biosciences 2026 Metformin (MET), a widely used antidiabetic drug, has recently gained attention for its anti-bone-resorptive properties. This study evaluated these effects in apical periodontitis (AP) and explored its underlying molecular mechanisms particularly its role in osteoclastogenesis.... Öffnen
apical periodontitis PubMed Sidt2 Knockdown Aggravates Apical Periodontitis Via Autocrine Tumour Necrosis Factor-Alpha. Li, Zhang, Du, He International dental journal 2026 Apical periodontitis (AP) is characterised by inflammatory infiltration and periapical bone loss, accompanied by high expression of tumour necrosis factor-alpha (TNF-α). SID1 transmembrane family member 2 (Sidt2) is a lysosomal membrane protein associated with inflammation. However, the effect of Si... Öffnen
biological dentistry PubMed Dental implant nanotopography for peri-implant tissue stability: soft-tissue sealing, innate immune calibration, and active biointerface regulation. Kondo, Yamada, Ambo, Egusa International journal of implant dentistry 2026 Peri-implantitis is a major biological complication in implant dentistry, associated with bacterial biofilm formation and amplified by dysregulated host immune responses. Increasing evidence indicates that implant and abutment surface properties influence not only osseointegration but also microbial... Öffnen
biological dentistry PubMed Interview with Neha Dinesh, American Society for Matrix Biology Founders Award Recipient. Leask, Fadl, Dinesh Matrix biology : journal of the International Society for Matrix Biology 2026 Andrew Leask and Asma Fadl interviewed Neha Dinesh, recipient of the American Society for Matrix Biology (ASMB) Founders Award at the ASMB meeting at Baltimore, November 2025.... Öffnen
biological dentistry PubMed Epigenetic Pathways Linking Prenatal Alcohol Exposure to Fetal Alcohol Spectrum Disorder. Pender, Beryoza, Khoodoruth, Makki, Khoodoruth Neuroscience and biobehavioral reviews 2026 Fetal Alcohol Spectrum Disorder (FASD) presents a profound global health burden, yet clinical diagnosis remains severely hindered by phenotypic heterogeneity and the lack of objective biomarkers. Emerging evidence reveals that the pathogenesis of prenatal alcohol exposure (PAE) is heavily driven by ... Öffnen
biological dentistry PubMed CXCL12-abundant reticular cell lineage is the key source of endosteal osteoblasts and adipocytes in adult bone marrow. Shibahara, Hirose, Abe, Usami, Hyodo, Hayashi, Motooka, Wakamori, Uzawa, Ohba, Toyosawa Regenerative therapy 2026 CXCL12-abundant reticular (CAR) cells, characterized by high expression of CXCL12, are perisinusoidal bone marrow stromal cells that establish the hematopoietic stem cell niche. Although CAR cells are postulated to become precursor cells of both osteoblasts and adipocytes, the spatiotemporal dynamic... Öffnen
biological dentistry PubMed Lactobacillus reuteri lozenges and chemotherapy-induced oral mucositis in breast cancer outpatients: an exploratory randomized controlled trial. Nishi, Horikoshi, Sasada, Kuwabara, Ohta, Shigeishi, Yoshioka, Konishi, Yoshida, Yoshimoto, Yano, Nakaoka, Shigematsu, Tanimoto, Kakimoto, Ohge, Kawaguchi Scientific reports 2026 Chemotherapy-induced oral mucositis impairs quality of life. Although probiotics may alleviate severe oral mucositis, previous studies mainly examined high-risk settings, such as hematopoietic stem cell transplantation. Prospective evidence for outpatient breast cancer chemotherapy remains limited. ... Öffnen
fusobacterium nucleatum PubMed Multidimensional Characterization of an Innovative Hybrid Phytocystatin for Acquired Pellicle Modulation and Initial Dental Erosion Prevention. Ferrari, Francese, Carlos, de Souza, Pessoa, Barros, Pollo, Câmara, Spagnol, Andrade, Oliveira, Henrique-Silva, Buzalaf Journal of dentistry 2026 This study presents the design, expression, and characterization of CaneStat, a recombinant hybrid protein combining domains of a sugarcane derived cystatin (CaneCPI-5) and a statherin phosphomimetic peptide (DDSt15).... Öffnen
biological dentistry PubMed Cross-kingdom dynamics of the subgingival bacteriome and mycobiome: a pilot study on the effects of a novel HA-H₂O₂-Glycine formulation to treat periodontitis. Gini, Farronato, Manunza, Ravasi, Abbruscato, Lorenzini, Stella Journal of dentistry 2026 Traditional periodontal therapy primarily focuses on bacterial biofilm control; however, recent evidence also suggests a critical role for the oral mycobiome. This study evaluated the clinical and ecological impact of a novel mouthwash formulation containing hyaluronic acid (HA), hydrogen peroxide (... Öffnen
biological dentistry PubMed Diagnosis, treatment and monitoring of pediatric Behçet's disease: Systematic literature review informing the ISSAID/PRES recommendations. Mastrolia, Romano, Piskin, Rigante, Poddighe, Demir, Sag, Zitoun, Ughi, Acikel, Venkateswaran, Park, Deiva, Tugal-Tutkun, Koné-Paut, Simonini, Demirkaya Autoimmunity reviews 2026 Pediatric-onset Behçet's disease (BD) accounts for up to 20% of cases and represents a distinct clinical entity characterized by evolving phenotypes and age-specific patterns of organ involvement. This systematic literature review synthesizes current evidence on pediatric BD, informing forthcoming r... Öffnen
artificial intelligence dentistry PubMed Artificial Intelligence in Dental Education: Overview of Teaching, Assessment and Academic Performance Prediction. Chuenjitwongsa, Arunratanothai, Rewthamrongsris, Sumrejkanchanakij, Tavedhikul, Samaranayake, Osathanon International dental journal 2026 Artificial Intelligence (AI) is increasingly used in dental education. The present study aimed to examine the current landscape of AI applications in dental education, focusing on their impact on teaching, assessment, and the prediction of academic performance. A literature search was performed base... Öffnen
biological dentistry PubMed Retraction notice to "Aggregatibacter actinomycetemcomitans serotypes and DGGE subtypes in Thai adults with chronic periodontitis" [Archives of Oral Biology 60 (2015) 1789-1796]. Pahumunto, Ruangsri, Wongsuwanlert, Piwat, Dahlen, Teanpaisan Archives of oral biology 2026 Kein Abstract... Öffnen
holistic dentistry PubMed Sociodemographic and gender affirmation factors associated with gender euphoria: a cohort study. Blacklock, Tollit, Pace, Elphinstone, Zwickl, Cheung, Pang, Buzwell EClinicalMedicine 2026 Gender euphoria encompasses positive feelings associated with gender expression, identity, and affirmation, and is important for wellbeing. However, little is known about how gender euphoria is experienced by different subgroups within trans communities. Such knowledge could contribute to a more hol... Öffnen
holistic dentistry PubMed Exploring Culturally Safe Oral Health Services for a Regional Aboriginal Community in Victoria. Collins, Andrews, Satur Community dentistry and oral epidemiology 2026 National policies have been introduced to promote the delivery of Culturally Safe dental care for Aboriginal and Torres Strait Islander Australians. However, the understanding of what constitutes Culturally Safe dental care and how it can be effectively implemented into clinical practice, remains li... Öffnen
holistic dentistry PubMed Changes in Oral Health-Related Quality of Life Following Restorative Dental Treatment of Untreated Dental Caries: A Prospective Study in the Saudi Population. Iqbal, Chaudhary, Alqahtani, Algarni, Alonazi, Alyahya, Arjumand, Siddiqui, Srivastava Oral health & preventive dentistry 2026 The effect of restorative dental treatment on oral health-related quality of life (OHRQoL) and general well-being in Saudi adults is not well-documented. This study therefore evaluated the sensitivity of the OHIP-14, OIDP, and WHOQOL-BREF instruments in capturing changes in OHRQoL and health-related... Öffnen
holistic dentistry PubMed Interrelationships among Smartphone Addiction, Eating Attitudes, and Body Mass Index in Healthcare Students: A Cross-sectional Analytical Study. Bharathwaj, Priya, Yi, Yan, Wen, Gunalan, Pillai, Parveen Annals of African medicine 2026 At present, rampant utilization of smartphones excessive smartphone has ingrained in the daily lives of university students, sequeling as a potential behavioral health concern. Recent findings suggest links between digital engagement, eating behaviors, and body mass index (BMI); that eminently remai... Öffnen
holistic dentistry PubMed European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction-associated steatotic liver disease. Mann, Lefere, Buytaert, Alisi, Arikan, Brecelj, Brown, Degrassi, Fiore, Fitzpatrick, Francque, Hudert, Janczyk, Johansen, Koot, Konidari, Lurz, Mandato, Mercadal-Hally, Moran-Lev, Mosca, Ranucci, Rogalidou, Rose, Socha, Vajro, Verduci, Vreugdenhil, Zavhorodnia, Zellos, Bruyne Journal of pediatric gastroenterology and nutrition 2026 Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disea... Öffnen
holistic dentistry PubMed Impact of dental prostheses on glycemic, nutritional, and oral health outcomes in patients with diabetes: A scoping review. Weng, Werdiningsih, Hasegawa, Sta Maria, Nagasawa, Shinmura Journal of prosthodontic research 2026 To map and synthesize the existing evidence on the association between dental prosthesis use and glycemic control, nutritional status, and oral health-related quality of life (OHRQoL) in diabetes.... Öffnen
holistic dentistry PubMed Urea supplementation is associated with holistic changes in suprathreshold non-volatile flavour perception through oral microbiome carbon metabolism. Zhang, Le Guennec, Shoaie, Carpenter NPJ science of food 2026 Urea is a small inorganic compound, readily available in saliva, that can be metabolised by the oral microbiome. We hypothesised that dietary supplementation with urea would increase salivary levels, alter microbial metabolism and, potentially, modify suprathreshold non-volatile flavour perception. ... Öffnen
holistic dentistry PubMed Histological assessment of budding, depth of invasion, and grading in oral squamous cell carcinoma: Correlation with regional metastasis. Abidullah Dental research journal 2026 Assessment of budding and grading of oral squamous cell carcinoma (OSCC) establishes the prerequisite for its management as the first step toward personalized management. The inclusion of depth of invasion (DOI) and its regional metastasis provides a holistic approach to the treatment of this devast... Öffnen
holistic dentistry PubMed Patient and dental practitioner acceptance of artificial intelligence in dental care: a cross-sectional study in Saudi Arabia's eastern province. Rifaat, AlNassar, AlQuraishi, AlQahtani, Wafai, Farooqi, Gaffar, Taymour Frontiers in oral health 2026 Artificial Intelligence (AI) is steadily emerging in dental health care field, yet successful implementation depends on stakeholder acceptance. Few studies have directly compared patient and dental practitioner perceptions within the same cultural and healthcare context.... Öffnen
holistic dentistry PubMed Cross-cultural Adaptation and Psychometric Evaluation of the Turkish Heidelberg Perianesthesia Satisfaction Scale. Saltalı, Sarı, Tosun, Çatak Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 2026 This study aimed to adapt and validate the Heidelberg Perianesthesia Satisfaction Scale (HPaSS) for use in the Turkish clinical setting. The scale holistically assesses patient satisfaction with anesthesia across the preoperative, intraoperative, and postoperative periods from the moment the surgica... Öffnen
integrative dentistry PubMed Towards person-centred integrated care for care-dependent older adults: How can prosthodontics contribute meaningfully? Tada Journal of prosthodontic research 2026 Kein Abstract... Öffnen
integrative dentistry PubMed Extension of prosthodontic digital guide workflow to reproduce lip-object spatial relationships: Application to an air-reed instrument. Hada, Fujiwara, Iwaki, Inokoshi, Kanazawa Journal of prosthodontic research 2026 This study aimed to extend the prosthodontic digital guide concept beyond intraoral applications by developing a method to capture and reproduce extraoral perioral spatial relationships using a digitally fabricated positioning guide in a proof-of-concept case.... Öffnen
artificial intelligence dentistry PubMed Automated classification of maxillary and mandibular dental views on intraoral photographs: a comparative benchmark study and mobile proof-of-concept. Yasin, Koklu, Alkanan, Gulzar BMC oral health 2026 Artificial intelligence is increasingly explored in dentistry to improve workflow efficiency and support image-based analysis. This study benchmarks deep learning (DL) and machine learning (ML) approaches for classifying pediatric dental views using a publicly available dataset of 9,562 intraoral im... Öffnen
integrative dentistry PubMed Sustained insulin-delivery as a growth factor for modulating oral mucosa healing: A case series. Miguel, Bonafé, Mathias-Santamaria, Nunes, Ramos, de Oliveira, Lopez, Casarin, Santamaria Archives of oral biology 2026 (s): In clinical practice, achieving a smooth recovery is essential, with an emphasis on optimizing therapeutic outcomes and ensuring patient comfort. The use of targeted therapies to modulate the host response toward resolution is highly desirable. Thus, this study aims to evaluate a novel sustaine... Öffnen
integrative dentistry PubMed Biological roles of extracellular proteins in Streptococcus mutans. Long, Wang, Liu, Ye, Yu, Wu, Fang, Munire, Wang, Liang, Zou, Ma Microbiological research 2026 Streptococcus mutans remains a key etiologic agent of dental caries by thriving in dysbiotic plaque biofilms that sustain low pH and abundant extracellular matrix. Although acidogenesis and extracellular polysaccharide (EPS) synthesis are long recognized virulence traits, accumulating evidence indic... Öffnen
integrative dentistry PubMed Performance of Advanced Large Language Models in Caries Risk Assessment and Preventive Decision-Making: A Multidimensional Evaluation of Five Chatbots. Sezer, Aydoğdu Caries research 2026 Large language models (LLMs) have recently been integrated into dental practice to support clinical reasoning and preventive decision-making. This study compared the performance of five advanced chatbots-ChatGPT-5, Claude 4.5 Sonnet, Gemini 2.5 Pro, LLaMA 3.1, and Mistral 7B-in providing evidence-ba... Öffnen
integrative dentistry PubMed Clinical utility of diagnosing lynch syndrome in gynecologic oncology: a joint statement from four japanese academic societies. Sato, Masuda, Oda, Kuwata, Nakajima, Yamada, Yamaguchi, Hirasawa, Mandai, Tanakaya, Ishida, Yoshino, Okamoto International journal of clinical oncology 2026 Lynch syndrome (LS) is an autosomal dominant cancer predisposition syndrome, associated with substantially increased risks of colorectal and gynecologic malignancies. Endometrial cancer may serve as a sentinel cancer for LS, placing gynecologists and gynecologic oncologists in a key position for ear... Öffnen
artificial intelligence dentistry PubMed Oral implanomics: transitioning from experience-based discipline to AI-driven therapeutic paradigm - radiomics and artificial intelligence in oral implantology. Ma Frontiers in oral health 2026 Oral implantology has experienced substantial digital transformation over the past two decades. The adoption of cone-beam computed tomography (CBCT), computer-assisted surgery, and artificial intelligence (AI) has improved diagnostic accuracy, treatment planning, and procedural precision. However, c... Öffnen
zirconia dental implants PubMed Educational quality and viewer engagement of Youtube videos on ceramic implants: a cross-sectional study. Baş, Durmuş, Kızılseki, Dağ BMC oral health 2026 Ceramic implants are increasingly used as metal-free alternatives to titanium implants because of their favorable esthetic properties and biocompatibility. As patients frequently seek dental information online, YouTube has become an important source of patient-oriented health information. This study... Öffnen
ceramic dental implants PubMed Randomized comparative crossover clinical study of mechanical and optical behavior, and oral health-related quality of life of CAD-CAM milled and 3D-printed complete-arch implant-supported interim restorations. Vasquez-Ramos, Cascos, Ballesteros-Martínez, Revilla-León, Gómez-Polo Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 Clinical evidence regarding 3D-printed complete arch interim prostheses remains limited. This randomized crossover trial was designed to compare mechanical complications between milled polymethylmethacrylate (PMMA) and a hybrid ceramic 3D-printed interim restoration and assess mechanical complicatio... Öffnen
zirconia dental implants PubMed A 3-Year Split-Mouth Randomized Non-Inferiority Controlled Trial Comparing Cement-Retained Monolithic CAD-CAM Zirconia and Lithium Disilicate Crowns for Single Posterior Implant Restorations. Yi, Wei, Quan, Kong, Huang, Jiang, Lin, Di Clinical oral implants research 2026 To evaluate whether monolithic CAD-CAM lithium disilicate (LS... Öffnen
ceramic dental implants PubMed Bioactive Coatings on Ti-Zr-Nb Alloy: Synthesis, Characterization and Implantology Potential. Kovalenko, Sukhyi, Fedak, Rimar, Kalinichenko, Yeromin, Shmychkova, Kulikov, Kovalyov, Sukhyi Materials (Basel, Switzerland) 2026 This research reports on the properties of oxide-ceramic coatings produced by plasma electrolytic oxidation in novel electrolyte solutions for implantology applications. A series of bioactive calcium-phosphate coatings was synthesized on medical-grade Ti-13Zr-13Nb alloy using the plasma electrolytic... Öffnen
ceramic dental implants PubMed Survival Rate and Biological Complications of Screw-Retained Ceramic-Veneered Implant-Supported Fixed Dental Prostheses: A Systematic Review and Meta-Analysis. Sheykhian, Garjan, Sharifi, Rahbar BioMed research international 2026 The present systematic review and meta-analysis were aimed at evaluating the survival rate and biological complications of screw-retained ceramic-veneered implant-supported fixed dental prostheses (ISFDPs).... Öffnen
ceramic dental implants PubMed In vitro analysis of a glass solder matrix on ATZ-ceramic-samples using human dental pulp cells and L929 mouse fibroblasts. Fuest, Dyck, Becerikli, Schmoock, Henningsen, Moss, Mau, Seitz, Friedrich, Gosau, Smeets, Matthies International journal of implant dentistry 2026 Optimized surface properties are a pivotal factor for dental ceramic implants and overall implant success. After grit-blasting and spray-coating Aluminum Toughened Zirconia (ATZ) ceramic samples with a glass solder, the biological cell response was examined and compared to uncoated and solely grit-b... Öffnen
ceramic dental implants PubMed Three-year clinical outcomes of additively manufactured hybrid composite implant-supported restorations fabricated through tilting stereolithography: a retrospective clinical study. Mangano, Mangano, Lerner, Loktionova, Dudnik, Malanova, Elovskaya, Maltseva, Dybov Journal of dentistry 2026 To evaluate the 3-year clinical performance of additively manufactured (AM) hybrid composite short-span implant-supported restorations fabricated through tilting stereolithography (TSLA) within a fully digital workflow.... Öffnen
ceramic dental implants PubMed Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One- and Two-Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study. Gul, Papia, Eqtesadi, Anderson, Becktor, Vult von Steyern Clinical oral implants research 2026 To evaluate the fracture resistance, fracture modes, and crystalline phase changes of zirconia one-piece implants (OPI) and bone-level (BLTPI) or tissue-level, two-piece implants (TLTPI), with ceramic (C) or titanium (T) abutment screws after dynamic preloading in a moist environment.... Öffnen
ceramic dental implants PubMed Biomechanical Behavior of Different Framework and Superstructure Material Combinations in Two-Implant-Supported Four-Unit Prostheses: A Dynamic Finite Element Analysis. Hajghani, Günal-Abdulcelil Materials (Basel, Switzerland) 2026 The long-term success of implant-supported prostheses (ISPs) is strongly influenced by material selection, which affects stress distribution within the implant system and surrounding cortical bone. This study aimed to assess the biomechanical behavior of a four-unit ISP supported by two implants in ... Öffnen
ceramic dental implants PubMed Performance of a new bone-level tapered two-piece zirconia implant manufactured by injection moulding: A pilot preclinical study in minipig mandibles. Hauck, Herber, Moecke, Balmer, Bellón, Kühl International journal of oral implantology (Berlin, Germany) 2026 The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established cylindrical, soft tissue-level ceramic implant with a single-lead thread ma... Öffnen
zirconia implants PubMed Prosthetic and Biological Complications of Metal-Zirconia versus Metal-Acrylic Implant-Supported Screw-Retained Complete-Arch Prostheses: A Systematic Review and Meta-Analysis. Marinkovic, Gutiérrez, Frey, Collao, Moreno, Miranda Journal of clinical and experimental dentistry 2026 Full-arch implant-supported screw-retained prostheses are widely used for the rehabilitation of edentulous patients. Conventional metal-acrylic hybrid prostheses have demonstrated acceptable clinical outcomes, however, mechanical complications, prosthetic wear, and biological issues remain concerns.... Öffnen
zirconia dental implants PubMed Fatigue Survival and Biomechanical Behavior of Two-piece Titanium and Zirconia Dental Implants. Melo de Matos, da Rocha Scalzer Lopes, Ramos, Coelho Sinhoreti, Souto Borges, Queiroz, Bottino Journal of clinical and experimental dentistry 2026 Titanium implants are considered the gold standard for oral rehabilitation; however, zirconia implants have emerged as a metal-free alternative with promising esthetic and biological properties. Despite these advantages, limited evidence is available regarding their long-term fatigue behavior and fr... Öffnen
zirconia implants PubMed Comparative finite element analysis of 3-unit implant-supported bridges restorated with different prosthetic materials in posterior mandible. Güney, Göze Saygın BMC oral health 2026 The aim of this study was to investigate the mechanical behaviour and stress distribution characteristics of different prosthetic materials (Co-Cr/porcelain; Zirconia/porcelain; Fibre- reinforced composite/Composite) used in mandibular posterior implant-supported fixed prostheses using finite elemen... Öffnen
zirconia implants PubMed Fracture resistance and failure modes in 4- vs. 6-implant supported zirconia full-arch prostheses with and without cantilevers: an Zhou, Cai, Xu, Jiang, Ren The journal of advanced prosthodontics 2026 To evaluate the fracture resistance and failure modes of IFCDPs supported by 4 versus 6 implants, with and without cantilever loading.... Öffnen
zirconia dental implants PubMed Surface-related factors affecting bacterial adhesion on dental implants: a short literature review. Choi The journal of advanced prosthodontics 2026 Dental implants offer a predictable solution for tooth replacement, yet peri-implant diseases, including peri-implant mucositis and peri-implantitis, remain a significant clinical concern and are primarily driven by bacterial biofilm formation on implant surfaces. The unique anatomy of peri-implant ... Öffnen
zirconia dental implants PubMed Chitosan coating effects on biological response to niobia-modified yttria-stabilized zirconia. Lau, Cha, Imazato, Yeo The journal of advanced prosthodontics 2026 The impact of chitosan (Ch) surface modification on the osseointegration of niobia-modified yttria-stabilized zirconia (Y,Nb-TZP) implants was assessed using a rabbit tibia model.... Öffnen
zirconia dental implants PubMed Stress distribution in three-unit implant-supported prostheses with different abutment designs: a finite element analysis. Guney, Tosun BMC medical informatics and decision making 2026 Implant-supported prostheses are widely used in posterior mandibular restorations, where biomechanical factors play a critical role in long-term performance. Abutment design may influence stress distribution within implant-supported systems, potentially affecting both prosthetic components and surro... Öffnen
zirconia implants PubMed Influence of abutment materials on peri-implant tissues health-a systematic review. Kheder, Rego, Mohammed, Hamdoon, Jerjes Biomaterial investigations in dentistry 2026 Abutment materials play a critical role in maintaining peri-implant tissue health, influencing both biological responses and aesthetic outcomes in implant-supported restorations. With the introduction of newer materials and digital fabrication techniques, an updated evaluation of their clinical perf... Öffnen
zirconia dental implants PubMed The influence of implant placement depth on peri-implant tissues in immediate implant placement: A randomized controlled clinical trial with 1-year follow-up. Alkimavicius, Rathi, Linkeviciute, Linkeviciene, Zekonis, Linkevicius Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 This clinical trial was carried out to compare the outcomes of immediate implants positioned 4 mm below free gingival margin versus deeper placement of 6 mm after a period of 1 year.... Öffnen
3D printed zirconia implants PubMed Wear resistance of 3D-printed and milled denture teeth materials for complete-arch implant-supported prostheses: An in vitro study. Sanchez, Lawand, Bazarbashi, Jreige, Marrano, Martin, Gonzaga, Rocha Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 The purpose of this in vitro study was to compare the two-body wear resistance of milled and 3D-printed denture teeth against various CAD-CAM prosthetic materials.... Öffnen
zirconia dental implants PubMed Zirconia Cantilever Resin-Bonded Fixed Dental Prostheses to Restore White and Pink Esthetics. Rotondo, Hant, Prott, Blatz Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2026 Replacing missing anterior teeth presents both functional and esthetic challenges, and selecting the most appropriate treatment requires careful consideration of patient age, specific needs, invasiveness, and long-term prognosis. While dental implants are frequently the treatment of choice, they are... Öffnen
zirconia dental implants PubMed Finite element analysis of the stress distribution in posterior zirconia implants: a systematic review. de Souza, Araújo, Martins, de Souza, Pires, Leite, Butler BMC oral health 2026 The aim of this systematic review was to assess the stress distribution of zirconia implants compared to titanium implants using finite element analysis (FEA). The main research question was whether zirconia demonstrate mechanical behavior comparable to or better than titanium in posterior applicati... Öffnen
NICO PubMed All-carbon 3D-structured electrodes by direct ink writing as electrocatalyst supports for alkaline freshwater and seawater electrolysis. Muñiz Muñoz, González-Ingelmo, Rodríguez Lagar, López García, Ruiz Esquius, Barreda, Santamaría, Blanco, Rocha Science and technology of advanced materials 2026 Water splitting is a key technology for green hydrogen production, yet important challenges persist, particularly as large-scale expansion is expected, with seawater electrolysis emerging as a promising alternative to mitigate freshwater limitations. Among these challenges, the development of active... Öffnen
NICO PubMed Scoping evidence review on the prevention and treatment of opioid overdose. Ghosh, Choudhury, Mahintamani, Clark, Krupchanka Harm reduction journal 2026 Opioid overdose is a public health crisis. Globally, ~ 600,000 deaths each year are attributable to drug use, and roughly three-quarters are linked to opioids. The rising prevalence of high-potency synthetic opioids like fentanyl necessitates comprehensive prevention and treatment strategies. This s... Öffnen
NICO PubMed Magneto-Responsive Hybrid Layered Double Hydroxides With Improved Electrochemical Performance and Field-Actuated Healing. Sebastian, Sarigamala Small science 2026 Overcoming the intrinsic transport limitations of hybrid supercapacitors using magneto stimulus-responsive layered double hydroxide (LDH) materials is a promising strategy. Here, we present an urchin-like Ni-Co LDH@CNT hybrid that exhibits extraordinary field-enhanced capacitance under a relatively ... Öffnen
NICO PubMed Hollow NiCo-LDH Nanocage Derived From ZIF-67 as an Efficient Catalyst for the Thermal Decomposition of Ammonium Perchlorate. Cheng, Zeng, Tang, Zhou, Li, Liu, Zhang, Liu, Huang Chemistry (Weinheim an der Bergstrasse, Germany) 2026 Heterogeneous catalysis achieves efficient thermal decomposition of ammonium perchlorate (AP) by creating abundant catalytically active sites and optimizing mass transfer and diffusion processes. Based on this, hollow nickel-cobalt-layered double hydroxide (H-NiCo-LDH) nanocages derived from metal-o... Öffnen
NICO PubMed Optimizing nickel and cobalt-based water oxidation electrocatalysts Luo, Moyo, Sun, Zhang, Zhu, Geng, Chen Chemical communications (Cambridge, England) 2026 Nickel (Ni) and cobalt (Co)-based oxides are promising candidates for the oxygen evolution reaction (OER). Many experimental studies have shown that incorporating iron (Fe) into Ni/Co-based materials can markedly enhance OER activity, while the degree of activity improvement strongly depends on how ... Öffnen
NICO PubMed Defect-Engineered Ni@Graphitic Carbon Catalyst With Adaptive Coordination for Energy-Efficient Plasma-Assisted Dry Reforming of Methane. Shen, Tong, Ma, Wang, Kawi, Chu, Ding Small (Weinheim an der Bergstrasse, Germany) 2026 Plasma-assisted dry reforming of methane (DRM) is a promising low-temperature strategy for syngas production. However, the dynamic and non-equilibrium nature of the plasma environment presents considerable challenges for catalyst design. Herein, we report a Ni@graphitic carbon catalyst featuring a t... Öffnen
NICO PubMed Geochemical Characteristics and Formation Environment of Mudstones in the Xueyuanhe Formation in the Raggyorcaka Area, Qiangtang Basin. Peng, Xie, Yue, Peng, Wang, Wang, Wang, Hu ACS omega 2026 The Permian source rocks in the Qiangtang Basin exhibit good potential for oil and gas exploration. Elucidating their organic matter enrichment mechanism and sedimentary paleoenvironmental characteristics is of great significance for evaluating the basin's Paleozoic oil and gas resources. This paper... Öffnen
NICO PubMed Vaccine strategies and development before and during the 1968 H3N2 influenza pandemic. Halwe, Krammer Vaccine 2026 Nearly 60 years ago, in 1968, the global population was confronted with the emerging pandemic influenza A virus (IAV) subtype H3N2 (1968 H3N2pdm). An estimate of up to two million fatalities have been linked to 1968 H3N2pdm, and the H3N2 subtype continues to circulate as seasonal IAV among humans un... Öffnen
NICO PubMed In Situ Quantification of Hydrogen Radicals Disentangles Direct and Hydrogen-Radical-Mediated Pathways in Green Ammonia Electrosynthesis From Nitrate. Cerrón-Calle, Arias-Sanchez, Flores, Roldan, Sánchez-Sánchez, Garcia-Segura Angewandte Chemie (International ed. in English) 2026 The electrochemical reduction of nitrate (ERN) to ammonia (NH... Öffnen
NICO PubMed Enhanced view/extended totally extraperitoneal plasty (eTEP) Rives-Stoppa repair versus open Rives-Stoppa repair: a single-center retrospective propensity score-matched cohort study. Klewitz, Pfander, Gruenewald, Hillebrecht, Fichtner-Feigl, Holzner, Hipp Surgical endoscopy 2026 To evaluate the comparative effectiveness of extended totally extraperitoneal plasty Rives-Stoppa retromuscular repair (eTEP-RS) and open Rives-Stoppa retromuscular repair (Open-RS) in patients undergoing ventral hernia repair.... Öffnen
cavitational osteonecrosis PubMed Human Umbilical Cord Mesenchymal Stem Cells Protect Against Steroid-Induced Osteonecrosis of the Femoral Head Through Hippo Pathway. Xing, Cai, Chen, Xu, Zhang, Zhong, Zhou, Peng Biomedicines 2026 Kein Abstract... Öffnen
RANTES CCL5 dentistry PubMed Neuralgia-inducing cavitational osteonecrosis (NICO): A scoping review of a controversial concept in orofacial pain. Biancardi, Cardoso, de Paula Almeida, Quirino, Sarmento, Rubira, Rubira-Bullen Archives of oral biology 2026 Neuralgia-Inducing Cavitational Osteonecrosis (NICO) is a debated diagnostic entity proposed as a cause of chronic orofacial pain. Despite ongoing clinical use, systematic evaluations integrating historical foundations and methodological gaps remain limited.... Öffnen
jawbone osteonecrosis PubMed Jawbone Cavitations: Current Understanding and Conceptual Introduction of Covered Socket Residuum (CSR). Ghanaati, Heselich, Lechner, Sader, Bouquot, Al-Maawi Bioengineering (Basel, Switzerland) 2026 Jawbone cavitations have been described for decades under various terminologies, including neuralgia-inducing cavitational osteonecrosis (NICO) and fatty degenerative osteolysis of the jawbone (FDOJ). Their biological nature and clinical relevance remain controversial. The present review aimed to su... Öffnen
jawbone osteonecrosis PubMed Mitigating thermal risk in guided implant surgery: Hollow-guide and alternative designs. Weatherington Clinical advances in periodontics 2026 The generation of heat during osteotomy preparation is a significant risk factor for thermal osteonecrosis, which may lead to implant failure. While static surgical guides enhance placement accuracy, they can physically obstruct the flow of external coolant, paradoxically increasing the risk for the... Öffnen
jawbone osteonecrosis PubMed Proteome and miRNAs Expression in Medication-Related Osteonecrosis of the Jaw. Allegra, De Salvo, Marcianò, Polito, Stagno, Carleo, Costanzo, Caterino, Ragusa, Licitri, Drago, Gasparo, Alberti, Khouyyi, Siniscalchi, Oteri, Bini, Macaione, Bianchi, Aguennouz International journal of molecular sciences 2026 Medication-related osteonecrosis of the jaw (MRONJ) is a complex condition associated with the use of antiresorptive drugs, such as bisphosphonates and denosumab. The condition is characterized by the presence of exposed bone in the maxillofacial region that fails to heal. MRONJ remains highly intra... Öffnen
jawbone osteonecrosis PubMed The Disappearing Jawbone. Sun, Ji, Wang, Zhang International journal of rheumatic diseases 2026 Kein Abstract... Öffnen
jawbone osteonecrosis PubMed Actinomyces lesions and acute inflammation predominate in osteonecrosis of the jaw associated with osteoclast-suppressing therapy in contrast to non-medication-related osteonecrosis. Kivelä-Rajamäki, Välimaa, Furuholm, Haglund, Sorsa, Hagström, Järvinen European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2026 Patients receiving antiresorptive therapy for cancer bone metastases/lesions or osteoporosis may develop osteonecrosis of the jaw. The pathogenesis remains unclear, but the condition has been associated with Actinomyces, co-pathogens, and pro-inflammatory activity. However, there are limited studies... Öffnen
jawbone osteonecrosis PubMed Early detection of medication-related osteonecrosis of the jaw (MRONJ) in patients with metastatic breast cancer using FDG-PET/CT scans. Emmelheinz, Egle, Abdel Azim, Augustin, Baumgart, Walch, Laimer, Bruckmoser, Rossetti, Bayerschmidt, Uprimny, Arvandi, Siebert, Marth, Brunner EClinicalMedicine 2026 Patients with osseous metastatic breast cancer receive bone-modifying agents (BMAs) as part of their standard care. Medication-related osteonecrosis of the jaw (MRONJ) is one of the most important toxicities of this class of drugs. MRONJ heavily impacts patients' quality of life and represents a maj... Öffnen
jawbone osteonecrosis PubMed Progress in Research on Medication-Related Osteonecrosis of the Jaw: From Pathophysiological Mechanisms to Clinical Treatment. Duan, Zhang, Han, Yuan, Mi, Dai, Bian, Wang Advanced biology 2026 Medication-related osteonecrosis of the jaw (MRONJ) is a severe oral disease induced by anti-resorptive and anti-angiogenic drugs. It is characterized by jawbone necrosis, infection, and impaired bone healing, severely affecting the patient's quality of life. Although the pathogenesis of MRONJ has b... Öffnen
jawbone osteonecrosis PubMed Unraveling Jawbone Susceptibility: Distinctive Features Underlying Medication-Related Osteonecrosis. Paczona, Piffkó, Janovszky Dentistry journal 2026 Medication-related osteonecrosis of the jaw (MRONJ) is a devastating complication arising primarily after invasive dentoalveolar procedures in patients treated with antiresorptive, antiangiogenic, or targeted therapies. Although recognized risk factors are established, the distinctive vulnerability ... Öffnen
RANTES CCL5 dentistry PubMed Expression of the Chemokine (C-C Motif) Ligand 5 (CCL5) in Oral Lichen Planus and Oral Lichenoid Lesions: A Systematic Review. Rampersaud, Al-Azzawi, Aria, Hijazi, Celentano, Fortuna Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 RANTES, a chemokine involved in regulating inflammatory responses, has been implicated in the pathogenesis of various diseases, including oral lichen planus (OLP). In this condition, the interaction between C-C motif ligand 5 (CCL5) and CC motif chemokine receptor 5 (CCR5) may contribute to the dest... Öffnen
RANTES CCL5 dentistry PubMed DMXAA accelerates orthodontic tooth movement via macrophage-mediated Rab13-enriched extracellular vesicle release and chemokine secretion. Wang, Zhang, Sun, Xu, Gu, Jin, Zhu, Zhang, Yan Progress in orthodontics 2026 Orthodontic tooth movement (OTM) is a complex process involving periodontal tissue remodeling, and safe strategies to accelerate OTM remain a research focus. DMXAA (Vadimezan), a non-toxic immune-modulating drug with established clinical trial data, stimulates the secretion of pro-inflammatory cytok... Öffnen
RANTES CCL5 dentistry PubMed Integrated Single-Cell Transcriptomics Identifies γδ T-Cell Heterogeneity and a Candidate HLA-E-NKG2A Regulatory Axis in Pancreatic Ductal Adenocarcinoma. Mandal, Hasan, Dhali, Maji Cancers 2026 Kein Abstract... Öffnen
RANTES CCL5 dentistry PubMed Transcriptomic characterization of platelet-rich fibrin-induced macrophage responses identifies U937 cells as a sensitive bioassay. Panahipour, Huang, Zampino, Miron, Gruber Frontiers in immunology 2026 Platelet-rich fibrin (PRF) is extensively utilized to enhance localized tissue healing, a process that critically depends on the transient polarization of macrophages toward a pro-inflammatory phenotype. Given that PRF, like other blood clot derivatives, may intrinsically modulate macrophage behavio... Öffnen
RANTES CCL5 dentistry PubMed Moderate Aerobic Training Causes Muscle Wasting in a DMBA-Induced Sarcoma Rat Model. Correia, Veras, Tavares, Batista, Cury, Oliveira, Fernandez, Counts, Gaafer, Ota, Frigo, Rodrigues, Sampaio, Chaves-Neto, Carvalho, Zimmers, Teixeira International journal of molecular sciences 2026 Cancer cachexia, characterized by severe body weight loss, negatively affects patient quality of life and survival. Although moderate exercise benefits healthy and chronically ill individuals, and the effect of exercise in cachexia generally appears beneficial, conflicting results have been reported... Öffnen
RANTES CCL5 dentistry PubMed Increased inflammation, disturbed extracellular matrix remodeling and reduced parotid and submandibular salivary gland function in male Wistar rats with type 2 diabetes. Kotowska-Rodziewicz, Zalewska, Żendzian-Piotrowska, Zukowski, Lo Giudice, Lo Giudice, Maciejczyk Dental and medical problems 2026 Insulin-independent type 2 diabetes mellitus (DM2) causes numerous organ complications, some of which involve the oral cavity. However, to date, the causes of reduced salivary secretion in patients with DM2 remain unclear.... Öffnen
RANTES CCL5 dentistry PubMed Nuclear Factor I-B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription. Chen, Rui, Fan, Yang, Geng, Lu, Ni, Huan, Shi, Wu, Yin, An, Lu, Zhao, Li Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Metabolic dysfunction-associated steatohepatitis (MASH) is a significant contributor to liver fibrosis due to hepatic stellate cells (HSCs) activation. The anti-apoptotic gene Nuclear Factor I-B (NFIB) has been implicated in regulating cell proliferation and differentiation in the context of liver i... Öffnen
focal infection theory dentistry PubMed [Historical evolution and current research of the odontogenic focal theory]. Xu, Duan, Zhou Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2026 Proposed in the early 20th century, the focal infection theory hypothesizes that teeth with dental caries, endodontic-periapical/periodontal diseases, plus impacted teeth and residual roots, might act as infection foci, inducing pathologies in distant organs including respiratory tract, gastrointest... Öffnen
oral systemic health PubMed A pediatric case of measles with gastrointestinal complications in an urban hospital setting: A clinical and public health perspective. Muse, Hassan, Ali, Muse, Nadarajah IDCases 2026 Measles remains a significant public health concern in under-immunized populations, often leading to complications such as dehydration and secondary infections.... Öffnen
oral systemic health PubMed Mapping oral-systemic health relationships: a data-driven analysis of co-occurrence patterns in biomedical literature. Patel, Wojtusiak JAMIA open 2026 To systematically map co-occurrence patterns between systemic medical conditions and oral diseases in the biomedical literature.... Öffnen
oral systemic health PubMed Tumor acid-triggered sericin prodrug colloidal system for enhanced photodynamic and ferroptosis therapy of breast cancer. Huang, Zhang, Wang, Xiao, Xu, Ran, Wan, Shi Materials today. Bio 2026 Image-guided tumor therapy is an integrated approach for visualized and targeted delivery, which synchronizes diagnosis and treatment to achieve complete tumor eradication. Reactive oxygen species (ROS) show promise for cancer therapy by provoking neoplastic oxidative damage; however, their therapeu... Öffnen
oral systemic health PubMed Association of carotid artery calcifications detected on panoramic radiographs with systemic diseases in dental implant patients: a cross-sectional study in a Turkish population. Bingul, Alkaya Karagoz BMC oral health 2026 Carotid artery calcification (CAC) detected on panoramic radiographs can serve as an early indicator of systemic atherosclerotic disease. This study aimed to determine the prevalence of CAC in digital panoramic radiographs of dental implant patients and to evaluate its association with systemic dise... Öffnen
oral systemic health PubMed Disparities in severe infection risk associated with systemic lupus erythematosus: evidence from a causal forest analysis. Zhao, Cheer, Xie Rheumatology (Oxford, England) 2026 Severe infections are a primary cause of morbidity and premature mortality in patients with Systemic Lupus Erythematosus (SLE). Although SLE patients are known to have an elevated average risk of severe infection, little is known about how this excess risk varies by patient characteristics. Populati... Öffnen
oral systemic health PubMed Dermatological manifestations associated with chemsex. Balado-Simó, Gimeno-Ribes, Riera-Monroig, Catalá-Gonzalo, Fuertes Journal of the European Academy of Dermatology and Venereology : JEADV 2026 Chemsex involves the use of psychoactive substances to facilitate or enhance sexual activity, particularly among gay, bisexual, and other men who have sex with men (GBMSM). Common substances used include methamphetamine, gamma-hydroxybutyric acid/gamma-butyrolactone (GHB/GBL), mephedrone, ketamine, ... Öffnen
oral systemic health PubMed Spiky mesoporous silica-based nanovaccines enhance mucosal immunity with improved intestinal retention and antigen accessibility. Yu, Shi, Yu, Cai, Zhao, Lin, Lu, Qiao, Fang, Fang, Yang, Wang Materials today. Bio 2026 Intestinal vaccination faces several key challenges, including limited epithelial interaction, inefficient antigen uptake, and insufficient immune stimulation. Here, we developed a virus-inspired oral nanovaccine based on spiky mesoporous silica nanoparticles (VMSNs) functionalized with ... Öffnen
oral systemic health PubMed Comparative Assessment of Salivary Neutrophil Gelatinase-Associated Lipocalin Levels (NGAL) Among Subjects With Periodontitis, Liver Cirrhosis, and Healthy Individuals: A Cross-Sectional Study. Dongare, Zope, Suragimath, Varma, Kale Cureus 2026 Periodontitis and liver cirrhosis are chronic inflammatory disorders characterized by dysregulated immune responses and an increased systemic inflammatory load. Neutrophil gelatinase-associated lipocalin (NGAL) is a neutrophil-derived biomarker implicated in inflammation, tissue injury, and systemic... Öffnen
oral systemic health PubMed Infected Patent Urachus Presenting As Umbilical Discharge in an Adult: A Case Report. Roach, Botelho, Muakkassa, McComb Cureus 2026 The urachus is an embryologic connection between the bladder and umbilicus that typically closes by the end of the first trimester. Failure of complete obliteration results in urachal anomalies, most commonly identified during infancy and rarely persisting into adulthood. Patent urachus in adults is... Öffnen
oral systemic health PubMed Exacerbated oral pyogenic granuloma in type 2 diabetes mellitus and advanced periodontitis: clinical management and pathophysiological insights: a case report. Alcaraz-Baturoni, Ibarra-González, López-Hernández, Alarcón-Sánchez, Ortuño-Sahagún, Heboyan, González-Cárdenas, Lomelí-Martínez Journal of surgical case reports 2026 Oral pyogenic granuloma (OPG) is a benign vascular proliferation that presents as a solitary, pedunculated, or sessile lesion, associated with irritative factors. Various systemic disorders, particularly type 2 diabetes mellitus (DM2), may contribute to its onset and progression through inflammatory... Öffnen
periodontitis cancer risk PubMed Microbial biomarkers for OPMD progression. Li, Wang, Chaurasia Advances in immunology 2026 Oral potentially malignant disorders (OPMDs) present a heterogeneous risk of progression to oral squamous cell carcinoma (OSCC), underscoring the need for reliable, non-invasive biomarkers to aid in clinical stratification. This chapter evaluates the utility of the oral microbiome as a source of pre... Öffnen
periodontitis cancer risk PubMed Periodontal symptoms, immunometabolic factors and autoimmune diseases: A prospective cohort study. Ni, Ye, Fan, Zhao, Liu, Mao, Chen Dental and medical problems 2026 Periodontal health is increasingly recognized as an integral component of systemic homeostasis. However, whether its disruption contributes to the development of autoimmune diseases (ADs) remains unclear in prospective settings.... Öffnen
periodontitis cancer risk PubMed Impact of periodontitis on the efficacy of neoadjuvant immunochemotherapy in non-small cell lung cancer: a multi-center real-world study. Li, Chen, Yin, Shen, Shen, Guo, Zhai, Wang, Kong, Xu, Luo, Pan, Pan International journal of clinical oncology 2026 Neoadjuvant immunochemotherapy has revolutionized non-small cell lung cancer(NSCLC) treatment. Periodontitis(PD) is one of the most prevalent oral diseases worldwide; however, its influence on the efficacy of neoadjuvant immunochemotherapy in NSCLC remains unclear. This study aimed to evaluate the a... Öffnen
periodontitis cancer risk PubMed Periodontitis-Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine-Mediated Acidosis Adaptation. Wu, Cai, Sun, Yu, Zhang, Zhang, Fan, Zhu, Ni, Cui, Wang, Li, Zhou, He, Wu, Zhang Cell proliferation 2026 Colorectal cancer (CRC) is the third most common malignancy worldwide. Epidemiological studies have suggested a positive association between periodontitis (PD) and CRC risk; however, the mechanistic basis underlying this relationship remains unclear. Extracellular vesicles (EVs) represent an importa... Öffnen
periodontitis cancer risk PubMed Periodontitis prevalence and effects on postoperative complications in gastric surgery: a prospective observational study. Pettersson, Vuorela, Louhimo, Hagström, Haglund, Sorsa, Seppänen, Hermunen BMC oral health 2026 Periodontitis, a progressive inflammatory disease of the tooth-supporting structures, has direct adverse effects on systemic health. Links between periodontitis and gastrointestinal tract malignancies have also emerged in numerous studies. The aim of our study was to uncover the prevalence of period... Öffnen
periodontitis cancer risk PubMed Overall survival and prognostic factors of oral cavity and oropharyngeal squamous cell carcinomas in Saudi Arabia: a population-based cohort study (2000-2019). Al-Amri, Al-Swuailem Frontiers in oncology 2026 Oral cavity and oropharyngeal squamous cell carcinomas (OC-SCC and OP-SCC) are major contributors to head and neck cancer mortality worldwide. However, long-term population-based survival patterns that separately evaluate these subsites remain limited in Saudi Arabia. This study assessed overall sur... Öffnen
periodontitis cancer risk PubMed Artificial Intelligence-Assisted Histopathologic Diagnosis and Grading of Oral Epithelial Dysplasia: A Systematic Review and Functional Meta-synthesis. Ardila, Pineda-Vélez, Díaz-Laclaustra Head and neck pathology 2026 Artificial intelligence (AI) has emerged as a promising tool for digital pathology, with potential applications in the histopathologic evaluation of oral epithelial dysplasia (OED). This systematic review synthesized current evidence on AI-assisted histopathologic diagnosis and grading of OED, focus... Öffnen
periodontitis cancer risk PubMed MRI-Based Radiomics and Artificial Intelligence for Prediction of Recurrence and Prognostic Outcomes in Oral Tongue Squamous Cell Carcinoma: A Systematic Review with Functional Meta-Synthesis. Ardila, Pineda-Vélez, Vivares-Builes, Díaz-Laclaustra Medical sciences (Basel, Switzerland) 2026 Oral tongue squamous cell carcinoma (OTSCC) remains clinically challenging because conventional clinicopathological markers do not fully explain variability in recurrence and survival. This systematic review and functional meta-synthesis aimed to identify and critically appraise studies using preope... Öffnen
periodontitis cancer risk PubMed A Systematic Review and Meta-Analysis of Risk Factors for Secondary Oral Squamous Cell Carcinoma After Allogeneic Hematopoietic Stem Cell Transplantation. Huang, Liu, Jiang, Tao Head & neck 2026 Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat patients with malignant and nonmalignant hematologic disorders. The development of secondary malignancies is recognized, especially secondary oral squamous cell carcinoma (OSCC). This study aimed to evaluate and s... Öffnen
periodontitis cancer risk PubMed Clinical characteristics of medication-related osteonecrosis of the jaw in breast cancer patients receiving zoledronic acid versus denosumab: a retrospective cohort study. Kim, Hwang, Baek, Ahn Maxillofacial plastic and reconstructive surgery 2026 Breast cancer is the most common malignancy in women worldwide, and bone-targeting agents (BTAs) - particularly zoledronic acid and denosumab - are widely administered for bone metastasis, carrying a recognized risk of medication-related osteonecrosis of the jaw (MRONJ) with reported incidence rates... Öffnen
root canal cancer correlation PubMed Effect of Intracapsular Pressure on Pulp Sensitivity in Teeth Affected by Jaw Cysts: A Clinical Study Combined With Finite Element Analysis. Zhou, Mao, Lin, Lu, Lai, Wang, Chen International dental journal 2026 The objective of this research was to explore the relationship between intracapsular pressure (ICP) and pulp sensitivity in teeth affected by jaw cysts and to examine clinical and radiographic factors associated with variations in ICP.... Öffnen
root canal cancer correlation PubMed Why was the concordance rate of imaging and clinical diagnosis in cemento-osseous dysplasia low? A retrospective study of 55 cases. Li, Zheng, Tang, Shi, Ren, You, Liu BMC oral health 2026 The World Health Organization (WHO) recommends that cemento-osseous dysplasia (COD) be diagnosed based on imaging findings, avoiding biopsy when possible. This study aimed to evaluate the concordance between imaging and clinical diagnoses in 55 COD patients, and to identify key clinical and radiogra... Öffnen
oral microbiome cancer PubMed Harnessing the Microbiome for Head and Neck Cancer Therapy: From Mechanistic Insights to Translational Opportunities. Liu, Chen, Bai, Li Critical reviews in oncology/hematology 2026 The human microbiome, particularly the diverse microbial communities in the oral cavity and gut, plays a critical role in the pathogenesis, progression, and treatment response of head and neck squamous cell carcinoma (HNSCC). Emerging evidence indicates that specific microbial communities can bidire... Öffnen
oral microbiome cancer PubMed Comment on "Effect of the Oral Microbiota, Blood Metabolome, and Inflammatory Proteins on Oral Cavity Cancer: A Bidirectional Two-Sample Mendelian Randomization Study and Mediation Analysis". Li, He, Pan Journal of stomatology, oral and maxillofacial surgery 2026 Kein Abstract... Öffnen
oral microbiome cancer PubMed p38 MAP kinase senses short-chain fatty acids to attenuate Toll-like receptor signaling and intestinal inflammation. Wu, Shi, Xiao, He, Chen, Zhao, Liu, Luo, Jiang, Guo, Meng, Zhu, Li, Li, Liu, Li, Yang, Shen, Lu Science advances 2026 Toll-like receptor (TLR) signaling is critical for innate immune system. However, whether it is directly modulated by microbiota-derived metabolites remains unclear. Here, we show that the short-chain fatty acids (SCFAs) propionate and butyrate suppress TLR signaling by directly binding p38α MAP kin... Öffnen
oral microbiome cancer PubMed Adaptive graph learning of microbial phylogeny enables accurate and interpretable microbiome-based host phenotype prediction. Dong, Wang, Chen, Xu, Xu Applied and environmental microbiology 2026 The human microbiome is inherently structured by phylogeny, yet most predictive models treat microbial taxa as independent features, thereby underusing evolutionary information that may improve disease classification. While recent deep learning approaches have attempted to incorporate phylogeny, the... Öffnen
oral microbiome cancer PubMed Supplementation with 2'-fucosyllactose, a prebiotic human milk oligosaccharide (HMO), in a magnesium-containing medical food reduces chemotherapy-induced mucositis in Wistar rats. Kharait, Wilcox, Stockdale-Stanforth, Thakare Frontiers in nutrition 2026 Mucositis is a common debilitating complication of chemotherapy in cancer patients that limits enteral nutrition, causes diarrhea, dehydration and electrolyte wasting. 2'-fucosyllactose (2'-FL), a non-digestible oligosaccharide initially isolated from human milk, is critical in the development of ga... Öffnen
oral microbiome cancer PubMed Natural chlorophyll‑sodium alginate oral hydrogel for robust treatment of ulcerative colitis. Dai, Zou, Jiang, Wan, Zhao, Bai, Su, Sun International journal of biological macromolecules 2026 Ulcerative colitis (UC) is a chronic and relapsing inflammatory bowel disorder that may lead to debilitating symptoms and serious complications such as toxic megacolon, intestinal perforation, and colon cancer. Conventional oral therapies are often limited by poor bioavailability and significant adv... Öffnen
oral microbiome cancer PubMed Dark tea-derived exosome-like nanovesicles suppress hepatocellular carcinoma via inhibiting Akt pathway and modulating immune profiles. Zheng, Wang, Ying, Lv, Zhou, You, Fan, Ye, Luo, Chen, Zhang, Mou Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Accumulating evidence indicates the microbial fermentation enhanced the health benefits and potential anti-tumor effect of dark tea. However, low bioavailability and unclarified therapeutic mechanisms impeded its deeply application. Plant-derived exosome-like nanoparticles offered a promising option... Öffnen
oral microbiome cancer PubMed Overview of head & neck microbiota. Jayasinghe, Gunawardhana, Senevirathna Advances in immunology 2026 The human oral cavity and upper aerodigestive tract harbor one of the most complex microbial ecosystems in the body, comprising bacteria, fungi, archaea, and viruses that coexist in a finely regulated state of eubiosis. These multi-kingdom communities play fundamental roles in maintaining mucosal ho... Öffnen
oral microbiome cancer PubMed Introduction. Jams, Jayasinghe Advances in immunology 2026 Microorganisms colonize nearly all anatomical sites of the human body, with the oral cavity hosting one of the most diverse, accessible, and densely populated microbial ecosystems. The oral microbiome comprises a complex consortium of bacteria, fungi, viruses, archaea, and protozoa that inhabit dist... Öffnen
oral microbiome cancer PubMed The microbiome of the head and neck region. Chaurasia, Ponangi Advances in immunology 2026 The head and neck region is a host to a diverse and complex microbiome, comprising of very specific microbial communities across different anatomical niches such as the oral cavity, nasal sinuses, pharynx, larynx, salivary glands, and middle ear. The existence of these communities is determined by v... Öffnen
fusobacterium nucleatum PubMed Cytotoxic Lesions of the Corpus Callosum: A Single-Center Case Series of Eight Patients With an Emphasis on Infectious Etiologies. Yamashita, Saito, Matsumoto, Yoshida, Adachi Matsuzawa, Sanayama, Watanabe, Fukuchi Cureus 2026 Background and aim Cytotoxic lesions of the corpus callosum (CLOCCs) are transient lesions characterized by restricted diffusion on MRI and are associated with various infectious and noninfectious conditions. However, the clinical spectrum of infection-related CLOCCs, particularly those associated w... Öffnen
fusobacterium nucleatum PubMed Cryptogenic brain abscess: Right-to-left shunt in pulmonary arteriovenous malformation and hepatopulmonary syndrome. You, Zhang, Bai, Yin IDCases 2026 Pulmonary arteriovenous fistula (PAVF) and hepatopulmonary syndrome (HPS) both cause right-to-left shunting, allowing pathogens to bypass the pulmonary filtration barrier and enter systemic circulation, leading to brain abscess. Despite distinct etiologies, both share the same pathological pathway-r... Öffnen
fusobacterium nucleatum PubMed Phylogenetic and Functional Analysis of β-Glucanases in Tannerella forsythia Reveals Distinct GH16 Family Glycoside Hydrolase Lineages in Oral Bacteria. Chinthamani, Settem, Kauffman, Sharma Research square 2026 Kein Abstract... Öffnen
fusobacterium nucleatum PubMed Fusobacterium nucleatum and response to treatment in colon and rectal cancer: a systematic review. De Dosso, Deantonio, Iezzi, Christoforidis, Vannelli, Frattini, Garo Cancer treatment reviews 2026 Fusobacterium nucleatum (Fn) has been implicated in the progression of colorectal cancer (CRC), immune modulation, and resistance to systemic therapies. However, its role as a predictive biomarker of treatment response remains unclear. We conducted a systematic review to evaluate the association bet... Öffnen
fusobacterium nucleatum PubMed Fusobacterium nucleatum, succinate signaling, and immunotherapy resistance in colorectal cancer: clinical relevance and translational opportunities. Niu, Sun, Gong, Pan Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2026 Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Although immune checkpoint inhibitors have changed the treatment landscape in several tumor types, their clinical benefit in CRC remains largely confined to mismatch repair-deficient disease. Most colorectal cance... Öffnen
fusobacterium nucleatum PubMed Integrative oncology in colorectal cancer: evidence-based strategies from prevention through survivorship. Shen, Lou, Bai, Zhang, Xu, Huang Frontiers in oncology 2026 Colorectal cancer (CRC) is a leading global malignancy, with approximately 1.9 million new cases and over 900,000 deaths recorded in 2022, yet evidence-based integrative oncology strategies remain inconsistently incorporated into routine care. This narrative review synthesizes current evidence acros... Öffnen
fusobacterium nucleatum PubMed Oral microbiome dynamics across periodontitis severity stratified by type 2 diabetes status. Mi, Zhi, Sun, Li, Sun, Gu, Yang, Feng Journal of oral microbiology 2026 The oral microbiome serves as an effector of bidirectional promotion between periodontitis and type 2 diabetes mellitus (T2DM). However, the association between diabetes status and oral microbiota alterations and whether these patterns explained increased periodontitis severity remains unclearly ill... Öffnen
fusobacterium nucleatum PubMed Antibiofilm Property of Silver Diamine Fluoride Against Elected Periodontal Pathogens: An In Vitro Study. Zhang, Zhao, Chu International dental journal 2026 This in vitro study aimed to evaluate the antibiofilm effects of silver diamine fluoride (SDF) against key periodontal pathogens.... Öffnen
fusobacterium nucleatum PubMed Clinical isolates of Scano, Choudhury, Rojo, Hawkins, Crowhurst, Zaharas, Lavado, Greathouse Microbiology (Reading, England) 2026 Pathogenic bacteria adapt to distinct disease environments, but whether these adaptations create therapeutic vulnerabilities remains unclear. ... Öffnen
bioceramic sealer PubMed Short-term histopathological effects of direct peripheral nerve exposure to AH Plus® Bioceramic Sealer in rats: an exploratory assessment of Stemregen® supplementation. Yücel, Ocak, Gökdere, Dundar, Özercan Biomaterial investigations in dentistry 2026 Extrusion of root canal sealers into neurovascular tissues can result in rare but serious neurological complications, including paresthesia and neuropathic pain. This study aimed to evaluate the histopathological effects of direct peripheral nerve exposure to AH Plus® Bioceramic Sealer and to assess... Öffnen
bioceramic sealer PubMed Effect of preparation taper and sealer type on fracture resistance of mesiobuccal roots with MB2 canals in maxillary first molars: an in vitro study. Sarıyılmaz, Sarıyılmaz, Bayındır, Sessi̇z, Ercan BMC oral health 2026 The mesiobuccal roots of maxillary first molars frequently contain a second mesiobuccal (MB2) canal, where limited dentin thickness near the furcation may compromise root strength during instrumentation. This study evaluated the effects of MB2 preparation taper and sealer type on fracture resistance... Öffnen
tricalcium silicate sealer PubMed Physicochemical and biological properties of calcium aluminate cement-based sealers. Crowley, Shen, Terlier, Kirkpatrick, Loggins, Colmenar Journal of endodontics 2026 This study's aim was to evaluate the physicochemical and biological properties of two calcium aluminate cement (CAC) sealers, EndoCeramic (EC) and a prototype molybdenum-containing sealer (PS), compared to EndoSequence BC (BC) and AH Plus (AHP).... Öffnen
bioceramic sealer PubMed Effect of continuous wave of condensation on postoperative pain using bioceramic versus resin sealers: a randomized clinical trial. Defişet, Özata BMC oral health 2026 The clinical behavior of bioceramic sealers under heat-based obturation techniques remains insufficiently explored, despite their widespread clinical use. Although these materials are generally recommended for single-cone techniques, their performance when exposed to heat during warm obturation proc... Öffnen
bioceramic sealer PubMed Retreatability of root canals filled with gutta percha and a novel bioceramic sealer- a scanning electron microscopy study. Sindhuja, Bhasin, Kumar, Iandolo, Abdellatif, Ahmad, Acerra Journal of oral biology and craniofacial research 2026 To compare effectiveness of 5% acetic acid, 10% formic acid, and chloroform used adjunctively with a rotary retreatment system in removing a premixed calcium-silicate sealer (Ceraseal) and gutta-percha from root canals, using scanning electron microscopy (SEM) to quantify residuals across canal thir... Öffnen
bioceramic sealer PubMed Influence of heat-assisted obturation on the distribution and post-setting stability of a calcium silicate-based endodontic sealer in simulated lateral canals: an in vitro study. Monteagudo, Miola, Benítez, Castellanos, Del Campo-Rodríguez, Muñoz BMC oral health 2026 To evaluate the effect of heat-assisted obturation on the distribution of filling material within apical and coronal lateral canals, the composition of the filling materials present within these canals, and the radiographic and microscopic characteristics of the premixed calcium silicate-based endod... Öffnen
bioceramic sealer PubMed Comparative Efficacy of Rotary Versus Ultrasonic Supplementary Protocols for Bioceramic and Epoxy Resin Sealer Removal: A Micro-CT in Vitro Study. González, López, Pozos-Guillén, Navarrete-Olvera, Gutiérrez-Sánchez, Arteaga-Martínez, Garrocho-Rangel European endodontic journal 2026 This study aimed to compare the efficacy of 2 retreatment protocols - SClean® file and R1 ClearSonic™ ultrasonic tip - in removing bioceramic (EndoSequence BC Sealer®, CeraSeal®, Kerr®) and epoxy resin-based (AH Plus®) sealers using micro‑CT analysis. One hundred and four extracted single-rooted tee... Öffnen
bioceramic sealer PubMed A Contemporary Review of the Physical, Chemical and Biological Properties of Bioceramic Sealers. Altunkum, Kaya European endodontic journal 2026 Bioceramic sealers have attracted increasing attention in endodontics due to their potential biological and physicochemical properties, including bioactivity, ion release and possible chemical interaction with dentin. These materials have been suggested to support mineralisation, may contribute to s... Öffnen
bioceramic sealer PubMed YouTube As an Information Source for Bioceramic-Based Root Canal Sealers in Endodontics: A Cross-Sectional Study. Baris, Atli, Gumus Australian endodontic journal : the journal of the Australian Society of Endodontology Inc 2026 This study aimed to evaluate the content and quality of YouTube videos on bioceramic-based root canal sealers. A total of 43 videos were assessed using the Journal of the American Medical Association (JAMA), Global Quality Score (GQS) and Modified DISCERN (mDISCERN) measurement tools. Statistical an... Öffnen
tricalcium silicate sealer PubMed Fabrication and characterization of a bioactive glass and tricalcium silicate incorporated resin-based root canal sealer. Noorani, Mohammed, Nongman, Alawi, Karobari Journal of conservative dentistry and endodontics 2026 To synthesize and characterize an experimental bioactive glass (BG) and tricalcium silicate (TCS) incorporated resin-based root canal sealer and compare its microstructural and elemental characteristics with that of unmodified AH plus and BioRoot RCS.... Öffnen
tricalcium silicate sealer PubMed Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers? Baran, Oncu, Celikten Australian endodontic journal : the journal of the Australian Society of Endodontology Inc 2026 This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser scanning microscopy (CLSM). Eighty single-rooted human teeth... Öffnen
tricalcium silicate sealer PubMed Volumetric Stability and Interfacial Adaptation of Tricalcium Silicate-Based Cements Used in the Lid Technique: A Micro-Computed Tomography and Scanning Electron Microscopy Analysis. Nomura, de Lima Dias-Júnior, Paz Dotto, Barros Steffens, Cavalini Cavenago, da Silveira Teixeira, Tanomaru-Filho, Bortoluzzi, da Fonseca Roberti Garcia Journal of endodontics 2026 This in vitro study evaluated the volumetric stability and interfacial adaptation of tricalcium silicate-based cements with different consistencies (sealer and putty) applied using the Lid technique for retrograde filling in apical surgery.... Öffnen
tricalcium silicate sealer PubMed Physicochemical stability of contemporary endodontic sealers with distinct chemical bases under thermal stress: a multi-analytical approach. Keskin, Turk, Karakullukçu, Khayyati, Nuhoğlu Odontology 2026 The aim of this study was to evaluate the physicochemical stability and clinical handling properties of contemporary root canal sealers with different chemical bases (hydraulic calcium silicate, resin, and silicone-based) under thermal stress simulating warm vertical compaction (WVC) using a multi-a... Öffnen
tricalcium silicate sealer PubMed Nonsurgical Endodontic Management of Oehler's Type II Laporte, Mancino, Minoux Clinical case reports 2026 Kein Abstract... Öffnen
tricalcium silicate sealer PubMed Analysis of the long-term solubility and phases of five different root canal sealers in phosphate buffered saline: an Jalan, Shetty, Kumblekar, M, Shetty PeerJ 2026 The long-term success of root canal therapy depends substantially on the physicochemical stability of endodontic sealers, particularly their solubility and the development of stable crystalline phases during setting. Tricalcium silicate-based sealers (TSBSs) have shown promising biological propertie... Öffnen
tricalcium silicate sealer PubMed Comparative finite element analysis of internal root resorption treatment using various root canal filling materials. Karaağaç Eskibağlar, Erdem, Eskibağlar, Kaman BMC oral health 2026 BACKGROUND: This study evaluated the stress distribution in maxillary incisors with internal resorption (IR) filled with various root canal filling materials using finite element analysis (FEA). METHODS: A three-dimensional model of the maxillary central incisor was generated by scanning. Twenty-sev... Öffnen
tricalcium silicate sealer PubMed Evaluation of tissue response of experimental calcium silicate-based endodontic sealers: An in vivo study. Silva, Rodrigues, Sasso-Cerri, Tanomaru-Filho, Guerreiro-Tanomaru, Cerri European journal of oral sciences 2026 The aim of this study was to evaluate whether the experimental sealers, composed of tricalcium silicate (CaSi) and CaSi supplemented with calcium hypochlorite (CaSi-H), stimulate tissue repair. The tissue response of experimental materials was compared with commercially available materials Bio-C sea... Öffnen
3D printed zirconia implants PubMed Managing An Unexpected Cemento-Dentinal Tear with a 3D-printed Crown Generated Chairside: A Case Report with 2 years Follow Up. Azpiazu-Flores, Saponaro, Lin, Morton, Zandoná, Azer The International journal of prosthodontics 2026 A 65-year-old Caucasian female was seen for the treatment of a failing mandibular fixed dental prosthesis (FDP). When the abutment teeth were evaluated, tooth 44 had an extensive carious lesion and was determined non-restorable, and tooth 47 was deemed salvageable. The patient presented and accepted... Öffnen
3D printed zirconia implants PubMed Implementing 3D-printed indexing devices and contemporary scanning techniques for complete-arch implant-supported rehabilitations: A clinical case report. Azpiazu-Flores, Phuckdeedindan, Aldosari, Yang, Morton, Lin Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 A sixty-eight-year-old male presented to the dental clinic seeking a complete mouth rehabilitation. He exhibited generalized dental caries, dental staining, cervical lesions, fremitus, and anterior wear. After declining tooth-retaining options, he elected full-mouth extractions with immediately load... Öffnen
additive manufacturing zirconia PubMed Zirconia in dentistry: A 25-year bibliometric analysis of research trends, thematic evolution, and emerging frontiers. Zhang, Chen, Wu, Miao, Luo Journal of dentistry 2026 This bibliometric analysis aimed to map the global research landscape of zirconia in dentistry over the past 25 years, focusing on publication output, collaboration patterns, thematic evolution, and emerging research fronts.... Öffnen
3D printed zirconia implants PubMed Mechanical, translucency, tribological resistance, and biocompatibility of lithium disilicate glass-ceramics produced by ZrO Xia, Tong, Zhou, Ye, Xu, Feng, Zhu, Chen, Li, Lin, Wen, Ma Dental materials : official publication of the Academy of Dental Materials 2026 Lithium disilicate glass-ceramics (LDGCs) have become one of the most widely used dental prosthesis materials in clinical practice due to their excellent esthetics, biocompatibility, and enamel-like wear resistance. However, their inherent brittleness, limited mechanical strength, and progressive we... Öffnen
3D printed zirconia implants PubMed Evaluation of marginal and internal adaptation of implant-supported PEEK crowns fabricated by 3D printing, milling, and pressing: a micro-CT analysis. Mahrous, El-Shazly, Mansour, Shabaan, Mokhtar, Tawfik, Radwan BMC oral health 2026 OBJECTIVES: This study aimed to evaluate and compare the marginal adaptation and internal gap of implant-supported crowns fabricated from polyetheretherketone (PEEK) using CAD-CAM milling, heat pressing, and 3D printing, employing non-destructive micro-computed tomography (µCT). METHODS: This in-vit... Öffnen
3D printed zirconia implants PubMed Comparative analysis of chemical properties and biocompatibility among high ceramic filler-based 3D printed resins, low filler-based 3D printed resins and CAD/CAM ceramics. Zhang, Lim, Ma, Chen, Jin, Yim, Lee, Kim Clinical oral investigations 2026 OBJECTIVE: This study aimed to compare surface properties, degree of conversion (DC), short-term eluate levels, and biocompatibility between high-filler three-dimensional (3D) printed dental resins, low-filler 3D printed dental resins, and milled ceramic materials. MATERIALS AND METHODS: Two commerc... Öffnen
3D printed zirconia implants PubMed Artificial intelligence facilitated smile design for the rehabilitation of a fully maxillary edentulous patient with a complete arch implant-supported prosthesis: A dental technique. Lawand, Vera, Nessif, Gonzaga, Martin Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 This dental technique describes the use of an artificial intelligence (AI)-facilitated digital workflow in the rehabilitation of an edentulous maxilla with a complete-arch implant-supported prosthesis. The patient's 2D frontal facial photograph was merged with a 3D digitized wax-rim record base in A... Öffnen
3D printed zirconia implants PubMed Influence of different manufacturing materials on the accuracy and fitting of full-arch restorations using a photogrammetry scanner-In vitro study. Borella, Guimaraes, Mendonça, Khalil, Al-Tarawneh, Cooper, Mendonça Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 This study aimed to assess the accuracy of a photogrammetry scanner and evaluate the influence of four different manufacturing materials on the accuracy and fitting of full-arch restorations made using a photogrammetry scanner.... Öffnen
additive manufacturing zirconia PubMed Surface characteristics and initial supragingival biofilm formation on additively manufactured zirconia and resin: An in situ study. Lu, Wu, He, Xu, Zhu, Wang, Li Journal of dentistry 2026 This in situ study investigated initial supragingival microbial adhesion and biofilm formation on additively manufactured zirconia (AM-ZrO₂) and additively manufactured composite resin (AM-RMC) surfaces, using subtractively manufactured zirconia (SM-ZrO₂) as a control material.... Öffnen
additive manufacturing zirconia PubMed Microstructural impact of additive and subtractive manufacturing on the flexural strength of zirconia: A scoping review. Pinelli, de Freitas Vallerini, Tardelli, Dos Reis Journal of the mechanical behavior of biomedical materials 2026 Additive manufacturing (AM) and subtractive manufacturing (SM) are common techniques used for the fabrication of zirconia dental prostheses. However, variability in zirconia composition, AM technologies, and processing parameters has led to heterogeneous microstructural and mechanical results. This ... Öffnen
additive manufacturing zirconia PubMed The Effect of Different Polishing Systems on the Surface Roughness and Color Changes of Monolithic Zirconia Crowns: A Comparison of Additive and Subtractive Manufacturing. Ozkurt-Kayahan, Karabagli, Ozden, Takahashi, Ozer, Shimada The International journal of prosthodontics 2026 To evaluate the surface roughness and color stability of three-dimensionally (3D) printed zirconia crowns after treatment with three different chairside polishing systems, in comparison with conventionally milled zirconia.... Öffnen
additive manufacturing zirconia PubMed Effect of Cigarette Smoking on the Surface Roughness, Color, and Translucency of Zirconia Produced by Additive and Subtractive Manufacturing. Mahmutluoglu, Aydin, Soygun Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] 2026 To compare the surface roughness, color stability, and translucency of zirconia produced by additive manufacturing (AM) and subtractive manufacturing (SM) after exposure to cigarette smoking.... Öffnen
additive manufacturing zirconia PubMed Meso-Scale Modifications in Additively Manufactured Zirconia: Topographical Design and Its Influence on Cell-Material Interactions. Hetzler, Rues, Zenthöfer, Rammelsberg, Kühle, Lux, Erber, Roser Bioengineering (Basel, Switzerland) 2026 Additive manufacturing enables the fabrication of patient-specific zirconia devices with integrated surface features; however, the biological effects of meso-scale topographies remain insufficiently understood. This in vitro study evaluated the influence of defined meso-scale surface modifications o... Öffnen
additive manufacturing zirconia PubMed Biomimetic bone-matching DLP-printed gradient TPMS ceramic implants. Wang, Yan, Liu, Li, Zhao, Zhang Journal of the mechanical behavior of biomedical materials 2026 To overcome stress-shielding effects of homogeneous bone implants, this study fabricated triply periodic minimal surface (TPMS) scaffolds with 50-80% porosity gradients via digital light processing (DLP), mimicking the cortical-to-cancellous bone mechanical transition.... Öffnen
additive manufacturing zirconia PubMed Advancements in Individual Dental Implants: A State-of-the-Art Review of Materials and Technologies. Lukomska-Szymanska, Radwanski, Leski, Khan, Matinlinna Materials (Basel, Switzerland) 2026 This narrative review synthesizes current evidence on materials and manufacturing technologies for customized dental implants, highlighting their comparative advantages and limitations.... Öffnen
additive manufacturing zirconia PubMed Digital fit and positional trueness analysis of a crown seated on additively manufactured casts fabricated using different manufacturing trinomials and build orientations. Şencan, Dönmez, Diken Türksayar, Demirel Journal of dentistry 2026 To evaluate the fit and positional trueness of a crown seated on additively manufactured casts fabricated using different manufacturing trinomials and build orientations.... Öffnen
additive manufacturing zirconia PubMed The effect of toothpaste and thermal aging on extrinsically stained additively manufactured zirconia: A comparative study on surface roughness and stain durability. Galvao, Kale, Donmez, Tanrıkut, Carreiro, Wierichs, Al-Johani, Yilmaz Journal of prosthodontics : official journal of the American College of Prosthodontists 2026 The purpose of this in vitro study was to compare the average surface roughness (R... Öffnen
AI endodontics PubMed Large language model-driven Socratic questioning for endodontic case analysis: A randomised controlled trial. Liu, Huang, Zhan, Ye, Yang, Luo International endodontic journal 2026 Endodontic education requires structured clinical reasoning practise, but resource constraints often limit the delivery of case-based instruction. This study developed a large language model (LLM)-based Socratic questioning system for endodontic case-analysis training and evaluated its feasibility, ... Öffnen
AI endodontics PubMed Diagnostic accuracy of ChatGPT-5 in evaluating root canal treatment and periapical pathosis on periapical radiographs. Almutairi, Alnasser, Alharbi, Austah Restorative dentistry & endodontics 2026 : Artificial intelligence (AI) chatbots such as ChatGPT-5 (OpenAI) are increasingly used for dental radiograph interpretation, especially among patients seeking self-assessment. However, their diagnostic accuracy in endodontics remains unclear.... Öffnen
AI endodontics PubMed Long-term survival and success rates of immature versus root-end resected mature tooth autotransplants: part I of a retrospective cohort study. Zeller, Couso-Queiruga, Janner, Bornstein, Suter, Chappuis, Raabe Clinical oral investigations 2026 To compare the survival and success rates of autotransplanted immature teeth versus mature teeth treated with extraoral root-end resection (EORER), and assess inter-rater agreement in radiographic evaluation between oral surgeons (OS) and general practitioners (GPs).... Öffnen
AI endodontics PubMed AI-Based Detection of Proximal Caries Across Radiographic Modalities: A Systematic Review and Meta-Analysis. Wang, Fu, Zhou, Zou Dento maxillo facial radiology 2026 To evaluate diagnostic performance of artificial intelligence (AI) models in detecting proximal caries across different radiographic modalities.... Öffnen
AI endodontics PubMed Vascular remodeling and microvessel density in inflammatory radicular cysts: a CD34 immunohistochemical analysis. Iacov, Camen, Munteanu, Diaconu, Popescu, Boldeanu, Liliac, Andrei, Mogoantă, Dascălu, Pătru, Ţuculină Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2026 Inflammatory radicular cysts are lesions of endodontic origin in which chronic inflammation and tissue remodeling may support cyst expansion.... Öffnen
AI endodontics PubMed Artificial Intelligence in Dental Practice: Current Trends and Future Perspectives. Mascarenhas, Shetty, Mallya, Nayak Annals of African medicine 2026 The significance of artificial intelligence (AI) in several facets of dental care is highlighted in this paper. These days, AI is becoming more widely accepted and significant in many industries, notably in dentistry. The development of Chat Generative Pre-training Transformer shows how far AI has a... Öffnen
AI endodontics PubMed Can artificial intelligence diagnose the invisible? A scenario-based evaluation of AI performance in cracked tooth diagnosis. Eraslan Akyüz, Değirmenci, Eroğlu, Topçuoğlu Odontology 2026 This study aimed to assess the diagnostic performance of contemporary artificial intelligence (AI) models in structured diagnostic tasks for crack-associated dental conditions, using standardized clinical scenarios without radiographic input. A scenario-based cross-sectional design was conducted usi... Öffnen
AI endodontics PubMed Can Artificial Intelligence Be Utilised to Develop Point-of-Care Endodontic Microbiological Technologies? Fouad International endodontic journal 2026 Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity. However, these studies have not resulted in many ... Öffnen
AI endodontics PubMed Accuracy and Functional Performance of Artificial Intelligence-Based Automated Crown Design Systems: A Systematic Review and Meta-Analysis. Holiel, Al Nakouzi, Enrique Cuevas-Suárez, Flores-Ledesma, Drouri, Bourgi Biomedical engineering and computational biology 2026 Artificial intelligence (AI)-driven automated crown design is rapidly transforming digital restorative dentistry by enabling anatomically precise and functionally integrated crowns. This systematic review and meta-analysis critically evaluate whether AI-assisted crown design systems, including machi... Öffnen
artificial intelligence dentistry PubMed Bloom's taxonomy-based comparison of artificial intelligence and dental students in restorative dentistry. Akkurt, Yılmaz, Akgül BMC medical education 2026 The aim of this study is to compare the performance of three large language models (ChatGPT 5, Microsoft Copilot, and Google Gemini 3), with that of dental students using their responses to multiple-choice questions (MCQs) in restorative dentistry. Accuracy of responses were analyzed across the know... Öffnen
artificial intelligence dentistry PubMed Deep learning single-cell analysis for cytologic evaluation of oral potentially malignant disorders. McRae, Rajsri, Vigneswaran, Kerr, Redding, Thornhill, Murdoch, Speight, Ruel, Wolk, Ruff, McDevitt Scientific reports 2026 Oral potentially malignant disorders (OPMDs) such as leukoplakia and erythroplakia may harbor dysplasia or progress to oral squamous cell carcinoma (OSCC), yet visual inspection alone is unreliable for risk assessment. Cytology offers a minimally invasive adjunct, but conventional approaches depend ... Öffnen
artificial intelligence dentistry PubMed Assessment of treatment response in recurrent medulloblastoma using craniospinal MRI. Hennenberg, Hofer, Nemeth, Vollbrecht, Tukora, Mayr, Bolotin, Zelei, Racz, Barkhof, Slavc, Sabel, Lassaletta, Sterba, Leblond, Nyson, Torsvik, Chi, Schmook, Furtner, Mayerhoefer, Kasprian, Azizi, Gojo, Peyrl, Haider European journal of radiology 2026 To evaluate whether quantitative craniospinal MRI assessment of baseline tumor burden provides prognostic value in patients with recurrent, previously irradiated medulloblastoma undergoing MEMMAT (Metronomic Antiangiogenic) therapy.... Öffnen
artificial intelligence dentistry PubMed Prompt Framing and Evidence Requirements for AI-Generated Educational Responses in Dental Education: An Experimental Study. Hung, Ward, Cohen, Marx, Smit, Newman, Lipsky JMIR medical education 2026 Large language models (LLMs) are increasingly used in health professions education; however, the role of prompt design in shaping their outputs remains poorly understood in clinical training contexts. In dentistry, where the presentation of information, perceived credibility, and procedural reasonin... Öffnen
artificial intelligence dentistry PubMed Mapping the structure of an emerging field: A scientometric decoding of large language model applications in the dental field. Lin, Choi, Park The Japanese dental science review 2026 To map the knowledge structure of large language model (LLM) applications in the dental field (LADF) through a dual-database scientometric study that highlights trends, collaborations, hotspots, and future directions.... Öffnen
artificial intelligence dentistry PubMed Artificial intelligence for assessment of the relationship between the mandibular canal and third molars using CBCT and panoramic radiography: a systematic review. Araujo, Miranda-Viana, Salzedas, Takeshita BMC oral health 2026 Accurate assessment of the relationship between mandibular third molars and the mandibular canal is essential to reduce the risk of inferior alveolar nerve injury. Artificial intelligence (AI), including deep learning and convolutional neural network-based models, has been increasingly investigated ... Öffnen
artificial intelligence dentistry PubMed Exploring the landscape of artificial intelligence in dental and maxillofacial radiology: a bibliometric analysis of studies and trends. Amin Amiri, Korsapati, Anil, Mahapatro, Alotaibi, Joukar, Mansour-Ghanaei, Hassanipour, Keivanlou, Delbari, Hendi, Koochaki Annals of medicine and surgery (2012) 2026 The integration of artificial intelligence (AI) in dental and maxillofacial radiology is revolutionizing diagnostic accuracy and clinical decision-making. This bibliometric analysis investigates the research landscape, emerging trends, and scholarly impact of AI applications in this specialized fiel... Öffnen
cavitational osteonecrosis PubMed Could Silent Inflammation Originating in Jawbone Cavitations Play a Role in Activating the CCL5/CCR5 Axis in Female Breast Cancer? A Diagnostic and Therapeutic Gap in Osteoimmunological Interactions. Vasconcelos E Cruz, Perko, Doebis, Notter, Schick, Lechner OncoTargets and therapy 2025 Breast cancer (BC) is one of the leading causes of cancer mortality worldwide. The chemokine CCL5 and its receptor CCR5 have been demonstrated to be associated with tumour progression, immune evasion, and metastasis.... Öffnen
cavitational osteonecrosis PubMed Neuralgia Inducing Cavitational Osteonecrosis of the Jaw: Scientific Controversy or pseudoscience? Keith Journal of pain research 2025 Jawbone cavities have had a long history in dentistry and for many years they have been described and studied under several different pseudonyms. These cavities are thought to be responsible for a wide range of disease processes and symptoms, including orofacial neuralgia. In this article the existe... Öffnen
cavitational osteonecrosis PubMed Quantitative Real-Time RT-PCR Verifying Gene Expression Profile of Cavitations Within Human Jaw Bone. Ghanaati, Dohle, Schick, Lechner Biomedicines 2025 Kein Abstract... Öffnen
jawbone osteonecrosis PubMed Mechanistic insights into MRONJ from the role of type H vessels and bone density changes. Shen, Wu, Zhao, Xu, Huang, Zang, Xie, Lan Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2025 This study investigated how ossification patterns influence type H vessel formation and bone mineral density in bisphosphonate (BIS)-treated bones, aiming to explain jawbones' heightened susceptibility to medication-related osteonecrosis (MRONJ). A cross-sectional analysis of mandibular bone radiode... Öffnen
jawbone osteonecrosis PubMed Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy. Shuai, Chen, Jiang, Zhu, Su, Wei, Liu, Jin Journal of nanobiotechnology 2025 BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to validate ferroptosis as a therapeutic target. METHODS: We first demons... Öffnen
RANTES CCL5 dentistry PubMed Insights into the Anti-Inflammatory Effects of Soft Tissue Manipulation. Lowery, Mustaklem, Wakefield, Brown, Sasse, Baule, Street, Pradhan, Sandhu, Marciano, Eland, Loghmani, Chu Biology 2025 Soft tissue manipulation (STM) is widely used by physical therapists, massage therapists, athletic trainers, and osteopathic physicians to manage musculoskeletal pain, yet its biological mechanisms remain poorly understood. Preclinical studies indicate that STM can alter immune cell behavior in anim... Öffnen
RANTES CCL5 dentistry PubMed IRF6 C-terminal phosphorylation links inflammation and cell-cell adhesion in oral keratinocytes: implications for oral lichen planus. Osorio-Osorno, Parada-Sanchez, Cox, Cox BMC immunology 2025 Oral Lichen Planus (OLP) is classified by the World Health Organization as an Oral Potentially Malignant Disorder (OPMD). OLP is characterized by chronic inflammation, which may contribute to its malignant transformation. In this study, we examined whether Interferon Regulator Factor 6 (IRF6), a key... Öffnen
focal infection theory dentistry PubMed C. Edmund Kells' "High Spots on the Road in Root Canal Treatment:" Historical & Contemporary Perspectives on his 1926 dictates. Manjarrés, Méndez, Gutmann Journal of the history of dentistry 2025 Kein Abstract... Öffnen
root canal cancer correlation PubMed Evaluation of three obturation techniques in 3D-printed models of oval canals with standardized prepared morphology: a micro-CT study. Xia, Gu, Song, Liu, Deng, Qian BMC oral health 2025 The complex and irregular morphology of prepared oval root canals poses optimal sealing in oval canals as a key endodontic challenge. To address this, this study utilized five types of standardized 3D-printed models replicating prepared anatomy of extracted teeth with oval canal, to characterize the... Öffnen
root canal cancer correlation PubMed A clinical study on the preservation of pulp sensitivity in affected teeth with jaw cysts using concentrated growth factor: a retrospective Cross-sectional study. Zhou, Mao, Shi, Lu, Lai, Wang, Li, Chen Scientific reports 2025 Jaw cysts commonly affect the oral and maxillofacial region. This study aimed to evaluate the effect of Concentrated Growth Factor (CGF) application during jaw cyst surgery on postoperative pulp sensitivity changes in affected teeth. This retrospective cross-sectional study included fifty-one patien... Öffnen
root canal cancer correlation PubMed Radicular Cysts and Periapical Granulomas: Data Documentation for 696 Cases and Findings on Fibrosis, and Porphyromonas gingivalis and Fusobacterium nucleatum in These Lesions. Virkkunen, Kaarela, Laine, Suominen, Hagström, Sorsa, Haglund Clinical and experimental dental research 2025 The objective of our study was to re-evaluate periapical lesions, including radicular cysts (RCs) and periapical granulomas (PGs) for locations, histopathological features, and degree of fibrosis in relation to the inflammatory response. In addition, we examined the presence of Porphyromonas gingiva... Öffnen
root canal cancer correlation PubMed Metastatic Status and Dissection Effect of Regional/Extraregional Lymph Nodes in Japanese Patients with Squamous Cell Carcinoma of the Anal Canal: A Multicenter Retrospective Cohort Study. Torigoe, Hirata, Yamada, Ajioka, Sugihara Journal of the anus, rectum and colon 2025 Squamous cell carcinoma of the anal canal (SCCA) is a rare condition. Standard treatment includes chemoradiotherapy, with surgical treatment reserved for limited cases. In the future, the decrease in surgical frequency makes it more difficult to pathologically assess the depth of tumor invasion and ... Öffnen
tricalcium silicate sealer PubMed Effect of powder particle size on hydration rates, permeability and antimicrobial properties of tricalcium silicate in root canals. He, Wang, Hao, Xiong, Cheng, Lou, He, Li, Qin Journal of materials science. Materials in medicine 2025 This study investigated the impact of particle size refinement on the hydration rate, permeability, and antimicrobial properties of tricalcium silicate (C... Öffnen
3D printed zirconia implants PubMed Complete Dual-Arch All-on-4® Rehabilitation Using a Fully Digital Workflow: A Case Report. Schuh, Birinci Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) 2025 This article presents a case report describing a fully digital workflow for a dual-arch All-on-4® rehabilitation, highlighting the integration of intraoral and facial scanning, mandibular motion tracking, prosthetically driven implant planning, guided surgery, and computer-aided design/computer aide... Öffnen
cavitational osteonecrosis PubMed Comparison of Cytokine RANTES/CCL5 Inflammation in Apical Periodontitis and in Jawbone Cavitations - Retrospective Clinical Study. Vasconcelos E Cruz, Notter, Schick, Lechner Journal of inflammation research 2024 Apical periodontitis (AP) is one of the most common endodontic diseases associated with osteo destructive cytokine production. The literature also reports cytokine studies in fatty degenerative osteonecrotic bone marrow defects (BMDJ/FDOJ) independent of AP.... Öffnen
focal infection theory dentistry PubMed Update on Focal Infection Management: A Czech Interdisciplinary Consensus. Peřina, Šmucler, Němec, Barták International dental journal 2024 The focal infection theory has been used to explain several chronic systemic diseases in the past. Systemic diseases were thought to be caused by focal infections, such as caries and periodontal diseases, and dentists were held responsible for these diseases due to the spread of oral infections. As ... Öffnen
root canal cancer correlation PubMed Macrophage polarization in human periapical lesions in relation to histopathological diagnosis, clinical features and lesion volume: An ex vivo study. Visarnta, Ratisoontorn, Panichuttra, Sinpitaksakul, Chantarangsu, Dhanuthai International endodontic journal 2024 To evaluate M1 and M2 macrophage polarization in radicular cysts and periapical granulomas through an immunohistochemical analysis and the correlation between macrophage polarization and histopathological diagnosis, clinical characteristics and lesion volume using cone-beam computed tomography.... Öffnen
root canal cancer correlation PubMed Geo-spatial epidemiology of gallbladder cancer in Bihar, India. Sakamoto, Kumar, Choudhary, Bishwapriya, Ghosh The Science of the total environment 2024 Recently, a substantial increase in gallbladder cancer (GBC) cases has been reported in Bihar, India. The region's groundwater can naturally contain harmful concentrations of arsenic, which appears to be epidemiologically linked to the unusually high incidence. However, the root causes remain largel... Öffnen
root canal cancer correlation PubMed Expert consensus on difficulty assessment of endodontic therapy. Huang, Wang, Liang, Ling, Bian, Yu, Hou, Chen, Li, Ye, Cheng, Xu, Hu, Wu, Guo, Su, Chen, Qiu, Chen, Wei, Huang, Yu, Lin, Zhang, Yang, Zhao, Pan, Yang, Wu, Pan, Xie, Deng, Huang, Zhang, Yue, Zhou International journal of oral science 2024 Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and preven... Öffnen
root canal cancer correlation PubMed A Case of Respiratory Epithelium-Lined Cyst with Enriched Nociceptor Innervation. Diogenes Journal of endodontics 2024 Apical lesions of endodontic origin can be classified as either granulomas or cysts. In rare cases, respiratory epithelium can proliferate and encapsulate a lesion, forming a cyst. Moreover, the innervation of apical lesions has only been previously reported in animal models of apical periodontitis.... Öffnen
cavitational osteonecrosis PubMed Response to the letters to the editor: Neuralgia-inducing cavitational osteonecrosis-A systematic review. Sekundo, Wiltfang, Schliephake, Al-Nawas, Rückschloß, Moratin, Hoffmann, Ristow Oral diseases 2022 Kein Abstract... Öffnen
cavitational osteonecrosis PubMed When systematic reviews are not done by experts. Bouquot Oral diseases 2022 Kein Abstract... Öffnen
cavitational osteonecrosis PubMed Neuralgia-inducing cavitational osteonecrosis - A systematic review. Sekundo, Wiltfang, Schliephake, Al-Nawas, Rückschloß, Moratin, Hoffmann, Ristow Oral diseases 2022 To assess the aetiologic factors, proposed diagnostic means and treatment strategies for neuralgia-inducing cavitational osteonecrosis.... Öffnen
focal infection theory dentistry PubMed Association between Endodontic Infection, Its Treatment and Systemic Health: A Narrative Review. Niazi, Bakhsh Medicina (Kaunas, Lithuania) 2022 The 'Focal Infection Era in Dentistry' in the late 19th and early 20th century resulted in widespread implementation of tooth extraction and limited the progress of endodontics. The theory proposed that bacteria and toxins entrapped in dentinal tubules could disseminate systemically to remote body p... Öffnen